Reticular (YC F24) (@ReticularAI) header
Reticular (YC F24) (@ReticularAI) profile picture

Reticular (YC F24)

@ReticularAI

Better predictions, better choices

reticular.ai
Joined November 2024
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  • Followers151
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Photo by Reticular (YC F24) (@ReticularAI)
A First Step Towards Interpretable Protein Structure Prediction With SAEFold, we enable mechanistic interpretability on ESMFold, a protein structure prediction model, for the first time. Watch @NithinParsan demo a case study here w/ links for paper & open-source code 👇
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Just published our state-of-the-art polygenic scoring results. We're emphasizing our benchmarking methods, especially how we split. medrxiv.org/content/10.64898…
A family-aware All of Us benchmark for polygenic prediction and genomic machine learning

A family-aware All of Us benchmark for polygenic prediction and genomic machine learning

Polygenic risk scores (PRSs) have improved substantially in predictive performance, yet results remain difficult to compare across studies that differ in cohorts, phenotype definitions, and evaluat...

medrxiv.org
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Longer 🧵 breaking down our paper 👇 xitter.gq/johnyang100/status/190…
John Yang (@johnyang100) profile pictureJohn Yang
@johnyang10013 Mar 2025
If you’ve ever - thought AI protein folding is magical ✨ - wanted more than a pLDDT score 🔎 - or just think mech interp in bio is cool 🤓 then read the 🧵 👇 on our first paper towards interpretable protein structure prediction just accepted to workshops at ICLR
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For anyone going to ICLR, we'll be presenting our poster at the GEM, LMRL, SciFM, XAI4Science, and MLMP workshops. Stop by if you're curious about bio interp!
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Reticular (YC F24) retweeted
John Yang (@johnyang100) profile picture
John Yang
@johnyang10011 Nov 2024
Replying to @johnyang100 @NithinParsan
shoutout @liambai21 and @etowah0 for beating us to the punch on translating mech interp to protein language models. excited to see where these techniques will lead given the dense amt of coevolutionary + structure info learned by these models.
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Incredibly excited to launch publicly as part of @ycombinator's Fall 2024 Batch. Send us a DM if you're in the interpretability space or working in biotech. @johnyang100 and @NithinParsan
Y Combinator (@ycombinator) profile pictureY Combinator
@ycombinator11 Nov 2024
YC F24's @ReticularAI makes protein AI models controllable and interpretable to help steer protein design with limited biological data, reducing costly validation cycles. ycombinator.com/launches/ME3… Congrats on the launch, @NithinParsan and @johnyang100!
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