Assistant Professor in Pharmacology at University of Bristol | GPCRs and ion channels | molecular modelling and simulation. @robincorey.bsky.social
Bristol, England
Joined September 2013
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Robin Corey @robincorey.bsky.social retweeted
We are hosting the Circuits of Life conference this September 10th-12th in Bristol, UK ⚡🦠🧬 focussed on advancing design and understanding of de novo and natural bioenergetic proteins and enzymes.
Sign up for your free ticket here! Please share widely.
eventbrite.co.uk/e/circuits-…
Robin Corey @robincorey.bsky.social retweeted
I'm so excited to join this interdisciplinary community as a 2025 Schmidt Science Fellow!
After years behind a keyboard, I will be pivoting toward the wet lab. To unlock the true potential of ML for biology/biomedicine, we need high-quality data and robust evaluation 🔬🧫🧪
We are excited to announce our 2025 Schmidt Science Fellows! 32 early career researchers, nominated by the world’s leading research universities, who will take an interdisciplinary approach to advancing discovery schmidtsciencefellows.org/ne…
Robin Corey @robincorey.bsky.social retweeted
Excited to share our work on GPCR antagonism: Contrary to popular belief, inverse agonists can bind to and act via GPCR:G protein complexes. We show this at kappa-opioid receptors by cellular, radioligand binding and cryoEM studies. A 🧵: @USC @USCDornsife nature.com/articles/s41589-0…
Robin Corey @robincorey.bsky.social retweeted
Interested in doing MD simulations of protein-ligand dissociation? Check out our PLUMED tutorial on the new version of maze: plumed-tutorials.org/lessons…
Implementation: github.com/jakryd/plumed2-ma…
More details about PLUMED Tutorials in our collaborative work: arxiv.org/abs/2412.03595
Robin Corey @robincorey.bsky.social retweeted
🚨 Join us at 1PM on Fri 10th Jan, in C42 of BSB for Harvard University's Dr Clarissa Coveney's Snapshot Seminar 📷 "The regulation of joint shape and disease" More info:
@UoBPPN
@RobinCorey1
Sponsored by @physoc
#UoBPPN #PPNSnaps
Robin Corey @robincorey.bsky.social retweeted
⚠️ Join us at 1PM on Mon 16th Dec. in C42 of BSB for Translational Health's Dr Kevin Kemp's Snapshot Seminar 🧫
"Using blood cells for brain repair – Cell fusion in the nervous system"
More info: @UoBPPN @RobinCorey1
Sponsored by: @physoc
#UoBPPN #PPNSnaps #ThePhySoc
Robin Corey @robincorey.bsky.social retweeted
🙌🧬 Incredibly proud of the Wells Wood lab's results in round 2 of the @adaptyvbio protein design competition! All of our designs expressed and one of them bound to EGFR.😀🎉 Check out the list below for the different models and software that we used to do this. 👇 (1/4)
PROTEIN DESIGN COMPETITION ROUND 2
The long awaited results are here -- and they don’t disappoint!
📈 We doubled the number of proteins we tested in our lab from 200 to 400!
🧬 Out of those 400 proteins, 378 expressed (95% expression rate!)
🚀 Out of those 378 expressed proteins, 53 did successfully bind the target protein EGFR (that’s a 14% success rate, more than 5x of the success rate of the previous round just 2 months ago!)
💪 The best binders reached single-digit nanomolar affinities which is within the range of the commercially sold Cetuximab antibody by Merck
😎 30 out of 130 protein designers managed to design at least one binding protein
More details ⬇️
Robin Corey @robincorey.bsky.social retweeted
⚠️ Join us Monday 9th Dec at 1PM in C42 of BSB for Dr Jeremie Zappia and Dr Justyna Hinchcliffe's (@Dr_Hinch) Snapshot Seminars
Info: @UoBPPN @RobinCorey1
PPN Snapshot seminars are generously sponsored by The Physiological Society (@physoc)
#UoBPPN #PPNSnaps #ThePhySoc
Robin Corey @robincorey.bsky.social retweeted
Great news in the lab and congratulations to Emma 👏🏻👏🏻
The 2024 Professor Sir Colin Blakemore award goes to Professor Emma Robinson for her work in animal research transparency at @BristolUni 👏🏻
Robin Corey @robincorey.bsky.social retweeted
Exciting Opportunities at the University of Bristol!
1️⃣ Lecturer in Biological Sciences: Lead the Taught Masters in Bioinformatics.
2️⃣ PhD in Biochemistry: Fully funded for Black heritage students.
3️⃣ PhD in Physiology, Pharmacology & Neuroscience.
new.bbstem.co.uk/jobs?compan…
Robin Corey @robincorey.bsky.social retweeted
Sooo, what are you going to do this weekend?
How about addressing the next stage of your career and establishing a research group in a progressive, multidisciplinary & supportive environment?
Come work with us.
EXCITING JOB OPPORTUNITY 👇
We are recruiting 3 full time, permanent Assistant or Associate Professors to join our dynamic research & teaching environment
Host-Pathogen Interactions (x1)
Plant Sciences (x2)
Apply by 15 Dec 2024!
bit.ly/48J9LdN
#plantsci #hostpathogen
Robin Corey @robincorey.bsky.social retweeted
Excited to share my first, first-author manuscript on the role of Signal Peptide Peptidase in membrane protein quality control. Massive thanks to our collaborators, @Marius_Lemberg @donem_avci @RobinCorey1 and postdoc @MichaelvdWeijer @Dunn_School
journals.biologists.com/jcs/…
Robin Corey @robincorey.bsky.social retweeted
Check out @JamesLorriman 's paper on the mitochondrial import/cleavage of PINK1, including lots of surprises!
Super collaboration with @LabCollinson @RobinCorey1 & @adam_grieve (@BristolBiochem @UoBPPN @BristolUni)
@wellcometrust PhD funding (James)
biorxiv.org/content/10.1101/…
Robin Corey @robincorey.bsky.social retweeted
Excited to share our latest research on how cholesterol influences the clustering and plasma membrane curvature biogenesis of the influenza M2 proton channel using coarse-grained MD simulations! 🦠🧬 Read the paper here: pubs.acs.org/doi/10.1021/acs…
Robin Corey @robincorey.bsky.social retweeted
📢Join our FREE 'Interview With Confidence' workshop
Fun + interactive workshop to get prepared for #bioscience #PhD interviews!
Followed by Q+A with @SWBio_DTP🙃
🗓️Tues 26 Nov
Register (by 18 Nov)👉
12-2pm shorturl.at/umARt
OR
6-8pm shorturl.at/2PYeE
Robin Corey @robincorey.bsky.social retweeted
🔺️PhD project alert🔺️
Looking for an enthusiastic PhD student to join my lab in Bristol @UoBPPN @BristolUni, who is interested in circadian rhythms, incretins, and obesity.
Co-supervision by the amazing @A_Adriaenssens (UCL)
Apply now ⚠️ 📢
findaphd.com/phds/project/fu…
Robin Corey @robincorey.bsky.social retweeted
🚨 Join us at 1PM on 4th Nov. in C42 of BSB for Robert Drake & Marie Sabec's Snapshot Seminars 🧬🧪
For more info: @UoBPPN @RobinCorey1
PPN Snapshot Seminars are sponsored by The Physiological Society: @physoc
#UoBPPN #PPNSnaps #ThePhySoc
Robin Corey @robincorey.bsky.social retweeted
YAY! Our paper showing insertion of the fluorescent non-canonical amino acid Anap into SERT is out. We directly measure binding of ions, inhibitors and substrates, and estimate on- and off-rates. Grateful to @novonordiskfond, @DFF_raad & @Carlsbergfondet.
rdcu.be/dYkKR
Robin Corey @robincorey.bsky.social retweeted
⚠️ Join us TODAY at 1PM in C42 of BSB for Dr Rob Lane's Snapshot Seminar - "Harnessing kinetics and allostery to target the dopamine and opioid receptors"
For more info: @UoBPPN @RobinCorey1
Snapshots are sponsored by @physoc
#UoBPPN #PPNSnaps #ThePhySoc
Join us at 1PM on Mon 28th Oct. in C42 of BSB for University of Nottingham's Dr Rob Lane's Snapshot Seminar 🧫 "Harnessing kinetics and allostery to target the dopamine and opioid receptors"
More info: @UoBPPN @RobinCorey1
Sponsored by: @physoc
#UoBPPN #PPNSnaps #ThePhySoc
Robin Corey @robincorey.bsky.social retweeted
Join us at 1PM on Mon 28th Oct. in C42 of BSB for University of Nottingham's Dr Rob Lane's Snapshot Seminar 🧫 "Harnessing kinetics and allostery to target the dopamine and opioid receptors"
More info: @UoBPPN @RobinCorey1
Sponsored by: @physoc
#UoBPPN #PPNSnaps #ThePhySoc