Cancer immunology lab at Dana Farber Cancer Institute applying synthetic biology tools to develop novel immunotherapies. #Immunotherapy #NK #CARs #BacterialEng
Boston, MA
Joined October 2024
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We engineered a new class of immunotherapy by surface displaying cytokines (il15/18 and 21) on a gut bacteria. Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses | Nature Biotechnology nature.com/articles/s41587-0…
Romee Lab retweeted
Please check out our recent “In a Nutshell” article for brief updates on CAR-NK cell therapy for cancer. Lots of new exciting frontiers in the field! @lab_rezvani @MDAndersonNews @BrJHaem #CARNK #NK #Cell therapy. onlinelibrary.wiley.com/doi/…
Bacteria engineered to target cancer. Bacteria expressing an anti-tumor signaling protein can be a potent cancer immunotherapy on Vimeo vimeo.com/1020694795
Romee Lab retweeted
Researchers from @DanaFarber, have engineered E. coli to function as a "tumor GPS," guiding cancer-fighting therapies directly to tumors. Published in @NatureBiotech, this innovation could transform solid tumor treatment. (1/3)
Romee Lab retweeted
In a new study in @NatureBiotech, Rizwan Romee, MD (@romeerizwan) and @DanaFarber researchers look at how gut bacteria is engineered to act as a tumor GPS for immunotherapies.
More: dana-farber.org/newsroom/new…
Study: nature.com/articles/s41587-0…