Genomics data scientist leading comp bio & ML @NewLimit. Ex-@ShapeTX @JunoThera | @DamonRunyon Fellow w/ @JShendure. CrossFit, Ultimate, 🥃 , ☕️-phile.

San Francisco, CA
Joined January 2012
Ron Hause retweeted
Following breakthrough results, we’re bringing longevity medicine to human trials. We’ve raised a $435M Series C led by @foundersfund to make it happen. Reprogramming cell age has the potential to create more healthy years for everyone. We're closer than ever to realizing it.
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We’re hiring a computational biologist @newlimit! Come join us! Help us interrogate large-scale single-cell / Perturb-seq data to find strategies to make cells look younger without losing their identity. Creative/skeptical minds desired. job-boards.greenhouse.io/new…
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Ron Hause retweeted
.@newlimit's first reprogramming medicines will enter the clinic in the coming years. we're recruiting a clinical leader to guide these trials for a new class of medicines intended to keep patients healthier, longer. reach out if you or a colleague are a good fit.
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thanks for having us! getting to chat science with @jacobkimmel was super fun, and I really appreciated the thoughtful questions
Builders is back with episode 3. Hosts @josh_coyne and @LM_Braswell are joined by @LauraDeming, @untillabs and @jacobkimmel, @newlimit to discuss two of the most ambitious goals in biotech: preserving organs long-term and resetting the biology of aging. They discuss how cryo could ease the transplant shortage, why cellular reprogramming is moving from concept to clinic, and how AI is speeding up discovery. Full episode link in the comments.
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we're expanding our functional genomics team @newlimit we're recruiting both research associates & scientists. this team runs the world's largest reprogramming screens, first humanized in vivo screens, and pushes the frontier of genomics tech each month. we grow deliberately, so this is a rare chance to join. send me a DM with a one-liner about the project you're most proud of if you're interested. we'll push the top responses straight to an interview.
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Our latest, from the brilliant @wchenomics and @_Choi_Junhong, out in @Nature , is ENGRAM, a multiplex method for symbolic recording of signaling and cis regulatory activity to DNA. Final version (not in preprint) includes integration w/ DNA Typewriter. rdcu.be/dN62L
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Interested in learning more about how we use #generativeAI at @ShapeTx to produce candidates for RNA therapies? I wrote about how this breakthrough technology is transforming the world of drug discovery in @FastCompany: tinyurl.com/4xsmcy3r
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Interested in exploring how #GenerativeAI can be used to help change the way we do #GeneTherapy? If so, please consider joining our #AI department here at ShapeTX! We have a couple of positions open seeking passionate computational innovators at the inter…lnkd.in/grXDr9DC
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It's really disappointing when you try to access data in a manuscript to reproduce results but the authors decline and @CellCellPress editors don't care to get back to you.
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A fantastic pair of inaugural papers from Junyue Cao’s new lab at @RockefellerUniv. Huge improvements to sci-RNA-seq, in vivo metabolic labeling w/ sc readout and cool biology to boot. Lots to dive into!
Hello World! Thrilled to share the first two preprints from Cao lab at @RockefellerUniv. Both focus on understanding cell population dynamics in aging/AD through new single-cell genomic techniques, led by our fantastic @ziyu and Andras!
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Crazy disappointing that @amazon would rather pay to package and reship a new item that’s on sale today vs credit a price difference on something I purchased yesterday. #wasteful
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kircherlab.github.io is recruiting 2 PostDocs (tinyurl.com/HLpostDoc. tinyurl.com/igvfHLpostDoc). Apply by Oct 10, 22. We are part of #IGVF, analyze reg. variant effects (MPRAs/CRISPR screens) and develop new comp. models & tools w/ @JShendure, @NadavAhituv, @malte_spielmann.
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Interested in geeking out over completely novel and complex genomic datasets, learning and developing new bioinformatic and ML tools along the way? We are too. Come join our department here at Shape Therapeutics Inc. to help advanc…lnkd.in/gnVMS22j lnkd.in/g9ttm9Pa
Left my suit jacket on board, @AlaskaAir confirmed picking it up and agreed to FedEx it at my expense but now apparently can no longer seem to find it. Extremely disappointed as a long time fan of the airline. #sadpassenger
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Opportunity to join the fantastic Kircher lab! lnkd.in/gZ_X4Nag
Ron Hause retweeted
I strongly believe that all managers in a technical area must be technically excellent. Managers in software must write great software or it’s like being a cavalry captain who can’t ride a horse!
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