@RotavirusL

Rotahoosier molecular virologist, Training and advocating for my team of super scientists

 Indiana University, Bloomington, IN
biology.indiana.edu/about/faculty/patton-john.html
Joined November 2017
  • Tweets1.4K
  • Following877
  • Followers1.1K
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Tomorrow's vector technology! Cheers to the IU-Bloomington team and the GIVAX team for their amazing progress in using Rotavirus Platform Technology to create combination vaccines again rotavirus and other enteric pathogens.
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biorxiv.org/content/10.1101/…

Production of OSU G5P[7] Porcine Rotavirus Expressing a Fluorescent Reporter by Reverse Genetics

Rotaviruses are a significant cause of severe, potentially life-threatening gastroenteritis in the young of many economically important animals. Although vaccines against porcine rotavirus exist,...

biorxiv.org
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microbiologyresearch.org/con…

Recombinant rotavirus expressing the glycosylated S1 protein of SARS-CoV-2

microbiologyresearch.org
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journals.asm.org/doi/full/10…

T7 expression plasmids for producing a recombinant human G1P[8] rotavirus comprising RIX4414...

RV1 (Rotarix , GSK), the most widely used rotavirus vaccine, is formulated from the human G1P[8] virus RIX4414 (1, 2). To protect against rotavirus gastroenteritis, >24 million children received the...

journals.asm.org
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PattonRotaLab retweeted
Viruses MDPI@VirusesMDPI21 Sep 2023
🎉 Our new special issue is here: Rotaviruses and Rotavirus Vaccines 👉mdpi.com/journal/viruses/spe… Join us in uncovering insights on this fascinating topic and submit your work today! 🔬 #Science #Vaccines #research
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Totally agree - although I try not to do the re-write myself and instead leave comments/suggestions...guessing @ananya716 might say she could do without the "grimace face" comment
Chad Pecot, MD
@ChadPecot22 Jul 2021
A mentor’s love for their trainees can be measured in tracked changes
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PattonRotaLab retweeted
102Virus@102_virus3 Aug 2023
There is still a lot of work to do on this one, but it is starting to look like a #paramyxovirus (#measles, #mumps, #nipah, #hendra, #rsv) 😃 #Blender3D #MolecularNodes
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Terrific article by Asha Philip and Sannoong Hu demonstrating the use of rotavirus as a vector system for expressing glycosylated proteins. Recombinant Rotavirus Expressing the Glycosylated S1 Protein of SARS-CoV-2 biorxiv.org/content/10.1101/…

Recombinant Rotavirus Expressing the Glycosylated S1 Protein of SARS-CoV-2

Reverse genetic systems have been used to introduce heterologous sequences into the rotavirus segmented double-stranded (ds)RNA genome, enabling the generation of recombinant viruses that express...

biorxiv.org
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mdpi.com/2076-393X/10/9/1463 #ARS2023

Maintaining Momentum for Rotavirus Immunization in Africa during the COVID-19 Era: Report of the...

The 13th African Rotavirus Symposium was held as a virtual event hosted by the University of Nairobi, Kenya and The Kenya Paediatric Association on 3rd and 4th November 2021. This biennial event...

mdpi.com
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AAAND we have lift off: the #calicivirus2023 with the lecture in honor of norovirus discoverer Al Kapikian , given by Kim Green: “ a totally biased selection”
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Where are we now? Noroviruses and caliciviruses everywhere! #calicivirus2023
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#calicivirus2023
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#calicivirus2023 John Patton on combined rotavirus norovirus vaccine, from GIVAX. Based in re engineered rotavirus genomes to express some norovirus proteins. Concept: could this induce dual antibody responses. Choice of background strain of course is crucial.
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PattonRotaLab retweeted
News at IU@IUNewsroom20 Apr 2023
Cindy E. Hmelo-Silver, a Distinguished Professor in the @IUSchoolofEd, and Curtis M. Lively, a Distinguished Professor in the @IUCollege Department of Biology, have been elected to the American Academy of Arts and Sciences. news.iu.edu/live/news/28227-…

2 IU Bloomington professors elected to American Academy of Arts and Sciences

Cindy Hmelo-Silver, Distinguished Professor in the School of Education, and Curtis Lively, Distinguished Professor in the Department of Biology, were amon...

news.iu.edu
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Congratulations, Dr. Dai! A truly outstanding graduate student who has been studying the battle between rotavirus and the innate immune system. mBio 2022 Dec 20;13(6):e0299522
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youtube.com/watch?v=duBsawLs…

Developing vaccines to save children’s lives

To protect infants and children around the world from both rotaviru...

youtube.com
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You - yes YOU - are chock-full of DNA viruses, mostly silently biding their time, waiting to infect your children/grandchildren. Yes, it sounds like something from a horror movie, but it's also something that humans have experienced for thousands to millions of years.
Virus infections and immunity@awesome_viruses14 Apr 2023
Persistent childhood viruses are found in adult tissues, including internal organs, indicating the existence of a unique microbiome in our organs- the virome. doi.org/10.1093/nar/gkad199 #microbiome #virome @lpyori @DgPratas @MariToppinen @Espoonklaussi @SajantilaAntti @MaFePerdomoC
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John Patton will present his findings and a summary of his work during the Distinguished Faculty Research Award and Lecture on May 3. research.impact.iu.edu/more-… via @IUimpact
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The credit for this Award belongs to the wonderful group of talented students, postdocs, and technicians that have been part of my lab.
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defeatdd.org/blog/more-10-ye…
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