Respiratory Physician: tweets on #PulmonaryFibrosis #Sarcoidosis #COPD; focus #RespiratoryPhysiology & #Exercise #Physiology דר' סמיר נסייר
Israel
Joined March 2011
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Dr. Samir Nusair, MD 🇮🇱 retweeted
1/n
Just in time for #ATS2024 on the 1st #SingleCell Atlas of the peripheral immune system in IPF is OUT! “Single-cell profiling reveals immune aberrations in progressive idiopathic pulmonary fibrosis”
atsjournals.org/doi/abs/10.1…
below main points 👇🏼
#IPFImmuneCellAtlas
Dr. Samir Nusair, MD 🇮🇱 retweeted
More than that. Our ultimate goal is to move away from phenotypic to immune mechanistic (endotypic) based therapeutic decisions. So regardless how one calls the disease - therapies that target specific immune aberrations should be tried – at New Haven, CT
11/n Our ultimate goal is to shift to immune-based classifications for better therapies and outcomes in fibrotic lung disease. #CurePF4All biorxiv.org/content/10.1101/…
Dr. Samir Nusair, MD 🇮🇱 retweeted
I was surprised to see that cyclophosphamide was still an option in #scleroderma related ILD/#pulmonaryfibrosis
Q: Would you still offer Cy for such people with scleroderma related ILD?
36%yes
48%no
16%just show the results
25 votes • Final results Dr. Samir Nusair, MD 🇮🇱 retweeted
Residual lung abnormalities were seen in 11% of patients ~4 months after a discharge from a COVID-19-related hospitalization
How much of this will persist beyond that?
Is this priming the lungs leaving pts at risk of ILD?
Congrats @iain_INKLUDE @IPFdoc and all!
Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post–COVID-19 Study
🔓 Open Access
🔗 bit.ly/42pHpSy
Dr. Samir Nusair, MD 🇮🇱 retweeted
What causes dyspnea in #LongCovid? A beautiful study with histopathology reveals the answer. Cluster 3 may be particularly relevant for patients with continued symptoms and "normal" physiology.
bit.ly/3BJDeUF
Dr. Samir Nusair, MD 🇮🇱 retweeted
The prevalence and significance of ILAs in a large and relatively younger and apparently healthy chineses cohort. Definitions based on recent Fleischner society guidelines. Reticulation stands out as progression to fibrosis risk factor
#pulmonaryfibrosis
atsjournals.org/doi/full/10.…
Dr. Samir Nusair, MD 🇮🇱 retweeted
🔥Finally out online: the latest multisocietal guidance defining progression in fibrotic lung disease🫁 has arrived!
These long-awaited guidelines help better clarify disease definition and guide treatment
doi.org/10.1164/rccm.202202-…
What does this mean? Hang on to your hats! 🧵1/n
Dr. Samir Nusair, MD 🇮🇱 retweeted
First, to quickly touch on IPF, the diagnostic guidelines were made abundantly clear to help delineate IPF and non-IPF diseases. 🧵3/n
Dr. Samir Nusair, MD 🇮🇱 retweeted
We are excited to share our new @Cell paper, revealing important & diverse roles played by skin fibroblasts. Our research shows how perturbations in a subset of fibroblasts characterize the development of scleroderma (SSc), a deadly autoimmune disease
cell.com/cell/fulltext/S0092…
Dr. Samir Nusair, MD 🇮🇱 retweeted
The minute ventilation/carbon dioxide production relationship is relevant to a number of patient-related outcomes in COPD. Minute ventilation/carbon dioxide production, therefore, should be valued in the clinical management of these patients. bit.ly/3df2upH
Dr. Samir Nusair, MD 🇮🇱 retweeted
The #oxygen dissociation curve of #blood in #COVID19 (Böning, Kuebler, and Bloch) - new review in @AJPLung
ow.ly/7Jxy50FOVzN
Dr. Samir Nusair, MD 🇮🇱 retweeted
Data from Israel showing the clinical characteristics and outcomes of immunized patients who are hospitalized with COVID19. 40% were immunocompromised, most others with co-morbidities though some less serious like hypertension; 4% no co-morbid; mort 22%. ncbi.nlm.nih.gov/pmc/article…
Dr. Samir Nusair, MD 🇮🇱 retweeted
The role of impulse oscillometry in the management of asthma when forced expiratory manoeuvres are contraindicated: case series and literature review tandfonline.com/doi/full/10.…
Dr. Samir Nusair, MD 🇮🇱 retweeted
EDITORIAL: "Functional respiratory assessment: some key misconceptions and their clinical implications" from J Alberto Neder.
dx.doi.org/10.1136/thoraxjnl…
Dr. Samir Nusair, MD 🇮🇱 retweeted
Scientists from @UoDMedicine have announced key findings from two separate studies they believe could unlock the development of a new type of treatment for lung conditions, including Covid-19
buff.ly/35dvufm
Dr. Samir Nusair, MD 🇮🇱 retweeted
Simple slide but revolutionary idea that some pneumonia’s are not caused by a dominant acquired pathogen but a “dysbiosis” of resident microbes - microbiome science in 2020 is really exciting
What causes the dysbiosis? Virus? Host response? #ERSCongress @Leopoldo_Segal
Dr. Samir Nusair, MD 🇮🇱 retweeted
We are delighted to announce that the ELF Award 2020 goes to all respiratory healthcare professionals who have been working tirelessly on the frontline during the COVID-19 pandemic. 👏
Read the press release and watch the full video:
europeanlung.org/en/news-and…
#ERSCongress
Dr. Samir Nusair, MD 🇮🇱 retweeted
New Hypersensitivity Pneumonitis Guidelines🦜:
• Categories: Fibrotic & Nonfibrotic
• Outlines antigenic sources
• Defines radiographic patterns for:- typical/compatible/indeterminate
• Algorithmic approach for multidisciplinary HP diagnosis
atsjournals.org/doi/abs/10.1…
Dr. Samir Nusair, MD 🇮🇱 retweeted
Our latest paper, led by @drphilmol @rach_invernizzi is online now. Bacterial load is increased in cHP but not to level of IPF. Microbiome composition is specific to cHP and independent of extent of fibrosis #cureILD @lloyd_lab @ImperialNHLI @ATSBlueEditor bit.ly/2OLml4l
Dr. Samir Nusair, MD 🇮🇱 retweeted
The hashtag is #ERSCongress! Please use that one if you plan to join the conversation during the event 😀