Bénédicte Sanson's lab @PDN_Cambridge @Cambridge_Uni investigates morphogenesis in Drosophila.
Cambridge, England
Joined August 2018
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Congratulations @GuyBlanchard5 and @ElenaScarpa4 for having their work featured as Biomedical Picture of the day @BPoD_s ! To find out more about the video, have a look at this paper doi.org/10.1242/dev.202862
Quantitative analysis of 100s of #epithelialcell divisions reveals stresses & forces influencing #celldivision orientation in developing #drosophila embryo. Video & research by @GuyBlanchard5, @ElenaScarpa4 et al @SansonLab @PDN_Cambridge @Dev_journal. On bpod.org.uk/archive/2024/6/4
Our cell division orientation paper is out!
Our paper on how mechanics and patterning combine at metaphase to orient planar epithelial divisions in vivo just out in Development, with @ElenaScarpa4, Leila Muresan, @SansonLab, @PDN_Cambridge. Thread digest follows… 1/5
doi.org/10.1242/dev.202862
Morphogenetic movements can generate forces that pull on adjacent tissues and change cell behaviours through mechanics and mechanotransduction, but does this always happen? We find that #Drosophila germband extension is remarkably robust to mesoderm invagination. #morphogenesis
Computational analysis of gastrulating #Drosophila embryos by @SansonLab shows that polarized cell intercalation is robust to the force generated by #mesoderm invagination, though this slows down the rate of A-P cell elongation @PDN_Cambridge #PLOSBiology plos.io/4djx8g0
