We're a French clinical-stage biotech company developing ProTcell, a thymus-empowered T-cell progenitor platform to rapidly re-arm the immune system.

Paris, France
Joined April 2022
Our CSO, @olivier_negre is participating in the 7th Allogeneic Cell Therapies Summit in #Boston, where he will present a talk entitled "Developing Progenitor T-Cell Therapy to Maintain Effective & Diverse TCRs while Ensuring Safety."
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Prof. Marina Cavazzana, co-founder of #SmartImmune and pioneer of gene and cell therapy, is promoted to the rank of Commander in the French National Order of Merit. This distinction, announced in 2024, was presented to her today at the @Elysee Palace.
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#ISCT2025 &New Orleans have been good to @olivier_negre who has not only given a presentation on thymic reconstitution enhancement and shared a poster but also took second place at the ISCT 5K run! We're grateful for all the interest in our #ProTcell platform. @ISCTglobal
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Our CSO, @olivier_negre will be flying to New Orleans next week to present “Strategies to improve thymic reconstitution” at the @ISCTglobal CGT Immune monitoring and Immunobiology educational workshop. He'll also be presenting a poster and... running 5 km, of course!
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It's happening! We're delighted that Dr Tsai @jjjt_98, our research partner at @MSKCancerCenter, is presenting the fruits of our collaboration at the @ThymUS2025 Meeting. The results are exciting!
We're thrilled to announce groundbreaking results from our collaboration with Memorial Sloan Kettering's researcher, Jennifer Tsai, MD, PhD. Data has confirmed the protective effect of our ProTcell technology against tumors. thymusmeeting.org/schedule @jjjt_98
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Congratulations to our R&D teammates Juliette Paillet and @olivier_negre on completing the #ParisMarathon yesterday! Both achieved their personal time goals. Well done! 🏃‍♀️🏃‍♂️
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We're thrilled to announce groundbreaking results from our collaboration with Memorial Sloan Kettering's researcher, Jennifer Tsai, MD, PhD. Data has confirmed the protective effect of our ProTcell technology against tumors. thymusmeeting.org/schedule @jjjt_98
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As you may have read online, we are preparing our next chapter. We remain fully committed to bouncing back, and we will let you know about these new prospects as soon as possible. In the meantime, our activities are continuing! smart-immune.com/articles/up…
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We're thrilled that our co-founder Marina Cavazzana will present at the prestigious Henry Kunkel Society meeting in April! Prof. Cavazzana will discuss making #Tcell progenitors to speed up immune reconstitution. All the conference sessions will be available live.
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Join us next week at the Cell & Gene Therapy Manufacturing Conference in #Basel! Our CTO, Pierre Heimendinger, will be sharing insights on our T cell progenitor therapy production evolving processes, with a focus on automation and speed release. @imapac #CMC #Manufacturing
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#WorldCancerDay We stand with patients, caregivers, and the scientific community in advancing more accessible, effective, and durable immunotherapies—driving progress toward a future where transformative treatments are within reach for all.
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Deeper understanding of thymus repair is invaluable to develop T cell progenitor therapies like our lead asset SMART101. In fact, our R&D team has observed the regenerative properties of culture-produced T cell progenitors on the thymus, in preclinical models.
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February 4 is #WorldCancerDay, and to mark the occasion, our scientific minds will be at the heart of innovation. Meet Shabi Soheili and @olivier_negre, who oversee our R&D activities, at the #Innovation Forum organized by the Paris Saclay Cancer Cluster!
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The Smart Immune team wishes you a magnificent 2025! May this new year bring hope and medical progress for all patients in need. Together, let's keep pushing back the boundaries of cell therapies to transform lives. Happy New Year! 🎉 #ProTcell #CGT #Thymus #Immunity #Tcell
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Are you, or do you know, a good candidate to join us as an Analytical Development Technician? This is your opportunity to be part of a team advancing the first thymus-empowered allogeneic T-cell therapies. lnkd.in/egHcQUY9 #job #biotechjob #offer #emploi #cv #vacancy
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Are you, or do you know, a good candidate to join us as an Analytical Development Technician? This is your opportunity to be part of a team advancing the first thymus-empowered allogeneic T-cell therapies. lnkd.in/egHcQUY9 #job #biotechjob #offer #emploi #cv #vacancy
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