@SpatialBioHub

Solutions for the World of Spatial Biology

spatialbiohub.com
Joined February 2024
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Listen to EP4: Pathology Goes Spatial @SpatialBioHub Spotify: open.spotify.com/episode/5UVโ€ฆ Apple: podcasts.apple.com/us/podcasโ€ฆ
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Join us for a Q&A with Dr. Aneesh Acharya, Chief Commercial Officer at Molecular Instruments - @HCRimaging . ๐Ÿ‘‰spatialbiohub.com/aneesh-achโ€ฆ
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Enjoy a Q&A session with @zehemminger Zachary Hemminger, PhD, Co-Founder of @biocartography ๐Ÿ‘‰ spatialbiohub.com/zachary-heโ€ฆ

Zachary Hemminger, PhD โ€” Spatial Bio Hub

spatialbiohub.com
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๐‚๐ž๐ฅ๐ฅ ๐ญ๐ฒ๐ฉ๐ž ๐ฆ๐š๐ฉ๐ฉ๐ข๐ง๐  ๐ซ๐ž๐ฏ๐ž๐š๐ฅ๐ฌ ๐ญ๐ข๐ฌ๐ฌ๐ฎ๐ž ๐ง๐ข๐œ๐ก๐ž๐ฌ ๐š๐ง๐ ๐ข๐ง๐ญ๐ž๐ซ๐š๐œ๐ญ๐ข๐จ๐ง๐ฌ ๐ข๐ง ๐ฌ๐ฎ๐›๐œ๐จ๐ซ๐ญ๐ข๐œ๐š๐ฅ ๐ฆ๐ฎ๐ฅ๐ญ๐ข๐ฉ๐ฅ๐ž ๐ฌ๐œ๐ฅ๐ž๐ซ๐จ๐ฌ๐ข๐ฌ ๐ฅ๐ž๐ฌ๐ข๐จ๐ง๐ฌ โžก๏ธ nature.com/articles/s41593-0โ€ฆ โฌ…๏ธ #MultipleSclerosis #MS #Inflammation #SpatialTranscriptomics
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๐’๐ฉ๐š๐ญ๐ข๐š๐ฅ๐ฅ๐ฒ ๐ซ๐ž๐ฌ๐จ๐ฅ๐ฏ๐ž๐ ๐ ๐ž๐ง๐ž ๐ž๐ฑ๐ฉ๐ซ๐ž๐ฌ๐ฌ๐ข๐จ๐ง ๐ฉ๐ซ๐จ๐Ÿ๐ข๐ฅ๐ž๐ฌ ๐จ๐Ÿ ๐Ÿ๐ข๐›๐ซ๐จ๐ฌ๐ข๐ง๐  ๐ข๐ง๐ญ๐ž๐ซ๐ฌ๐ญ๐ข๐ญ๐ข๐š๐ฅ ๐ฅ๐ฎ๐ง๐  ๐๐ข๐ฌ๐ž๐š๐ฌ๐ž๐ฌ โžก๏ธ nature.com/articles/s41598-0โ€ฆ #Pathology #SpatialTranscriptomics #PulmonaryPathology #ILD #IPF #LME #CHP #NSIP
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๐€ ๐ฆ๐ฎ๐ฅ๐ญ๐ข-๐ฆ๐จ๐๐š๐ฅ ๐ฌ๐ข๐ง๐ ๐ฅ๐ž-๐œ๐ž๐ฅ๐ฅ ๐š๐ง๐ ๐ฌ๐ฉ๐š๐ญ๐ข๐š๐ฅ ๐ž๐ฑ๐ฉ๐ซ๐ž๐ฌ๐ฌ๐ข๐จ๐ง ๐ฆ๐š๐ฉ ๐จ๐Ÿ ๐ฆ๐ž๐ญ๐š๐ฌ๐ญ๐š๐ญ๐ข๐œ ๐›๐ซ๐ž๐š๐ฌ๐ญ ๐œ๐š๐ง๐œ๐ž๐ซ ๐›๐ข๐จ๐ฉ๐ฌ๐ข๐ž๐ฌ ๐š๐œ๐ซ๐จ๐ฌ๐ฌ ๐œ๐ฅ๐ข๐ง๐ข๐œ๐จ๐ฉ๐š๐ญ๐ก๐จ๐ฅ๐จ๐ ๐ข๐œ๐š๐ฅ ๐Ÿ๐ž๐š๐ญ๐ฎ๐ซ๐ž๐ฌ ๐Ÿ‘‰ nature.com/articles/s41591-0โ€ฆ #SpatialBiology

A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across...

Nature Medicine - Single-nucleus and single-cell RNA sequencing plus spatial profiling with four methods of core biopsies from 60 patients with metastatic breast cancer reveal patient-specific gene...

nature.com
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๐‘๐ž๐œ๐จ๐ฏ๐ž๐ซ๐ข๐ง๐  ๐ฌ๐ข๐ง๐ ๐ฅ๐ž-๐œ๐ž๐ฅ๐ฅ ๐ž๐ฑ๐ฉ๐ซ๐ž๐ฌ๐ฌ๐ข๐จ๐ง ๐ฉ๐ซ๐จ๐Ÿ๐ข๐ฅ๐ž๐ฌ ๐Ÿ๐ซ๐จ๐ฆ ๐ฌ๐ฉ๐š๐ญ๐ข๐š๐ฅ ๐ญ๐ซ๐š๐ง๐ฌ๐œ๐ซ๐ข๐ฉ๐ญ๐จ๐ฆ๐ข๐œ๐ฌ ๐ฐ๐ข๐ญ๐ก ๐ฌ๐œ๐‘๐ž๐ฌ๐จ๐ฅ๐ฏ๐ž sciencedirect.com/science/arโ€ฆ #SpatialTranscriptomics #SingleCellResolution #scResolve #CellTypeDeconvolution
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๐€ ๐ฉ๐ซ๐ž๐ง๐š๐ญ๐š๐ฅ ๐ฌ๐ค๐ข๐ง ๐š๐ญ๐ฅ๐š๐ฌ ๐ซ๐ž๐ฏ๐ž๐š๐ฅ๐ฌ ๐ข๐ฆ๐ฆ๐ฎ๐ง๐ž ๐ซ๐ž๐ ๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐จ๐Ÿ ๐ก๐ฎ๐ฆ๐š๐ง ๐ฌ๐ค๐ข๐ง ๐ฆ๐จ๐ซ๐ฉ๐ก๐จ๐ ๐ž๐ง๐ž๐ฌ๐ข๐ฌ โžก๏ธ nature.com/articles/s41586-0โ€ฆ โฌ…๏ธ #ISPC #StemCells #SpatialTranscriptomics #Angiogenesis #WoundHealing
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๐•๐ข๐ณ๐ ๐ž๐ง, ๐”๐ฅ๐ญ๐ข๐ฏ๐ฎ๐ž ๐Œ๐ž๐ซ๐ ๐ž, ๐…๐ฎ๐ซ๐ญ๐ก๐ž๐ซ ๐‚๐จ๐ง๐ฌ๐จ๐ฅ๐ข๐๐š๐ญ๐ข๐ง๐  ๐’๐ฉ๐š๐ญ๐ข๐š๐ฅ ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐Ÿ‘‰genengnews.com/topics/omics/โ€ฆ๐Ÿ‘ˆ #Vizgen #Ultivue #SpatialBiology

Vizgen, Ultivue Merge, Further Consolidating Spatial Biology

The combined companyโ€”which will carry the Vizgen nameโ€”will build upon its namesake predecessorโ€™s expertise in single-cell spatial genomics and Ultivueโ€™s leadership in multiplex proteomic profiling.

genengnews.com
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๐Ÿ”ฌ ๐Ÿงฌ ๐’๐ฉ๐š๐ญ๐ข๐š๐ฅ ๐จ๐ฆ๐ข๐œ๐ฌ ๐š๐๐ฏ๐š๐ง๐œ๐ž๐ฌ ๐Ÿ๐จ๐ซ ๐ข๐ง ๐ฌ๐ข๐ญ๐ฎ ๐‘๐๐€ ๐›๐ข๐จ๐ฅ๐จ๐ ๐ฒ โžก๏ธ cell.com/molecular-cell/fullโ€ฆโฌ…๏ธ #SpatialOmics #SpatialTranscriptomics #ISH #FISH #sequencing #genomics #InSitu #PolyA #SpatialBiology
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Hypoxia induces ROS-resistant memory upon reoxygenation in vivo promoting metastasis in part via MUC1-C ๐Ÿ‘‰ nature.com/articles/s41467-0โ€ฆ ๐Ÿ‘ˆ #TNBC #BreastCancer #pathology #FFPE #spatialbiology #spatialtranscriptomics
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๐…๐ข๐›๐ซ๐จ๐ญ๐ข๐œ ๐ซ๐ž๐ฌ๐ฉ๐จ๐ง๐ฌ๐ž ๐ญ๐จ ๐š๐ง๐ญ๐ข-๐‚๐’๐…-๐Ÿ๐‘ ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ฒ ๐ฉ๐จ๐ญ๐ž๐ง๐ญ๐ข๐š๐ญ๐ž๐ฌ ๐ ๐ฅ๐ข๐จ๐›๐ฅ๐š๐ฌ๐ญ๐จ๐ฆ๐š ๐ซ๐ž๐œ๐ฎ๐ซ๐ซ๐ž๐ง๐œ๐ž ๐Ÿ‘‰๐Ÿ‘‰ lnkd.in/gQSDeAQ2 ๐Ÿ‘ˆ ๐Ÿ‘ˆ #glioblastoma #fibrosis #spatialbiology #digitalpathology #multiomics #spatialomics ๐Ÿง  ๐Ÿงฌ๐Ÿ”ฌ
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๐’๐ฉ๐š๐ญ๐ข๐š๐ฅ ๐ญ๐ซ๐š๐ง๐ฌ๐œ๐ซ๐ข๐ฉ๐ญ๐จ๐ฆ๐ข๐œ๐ฌ ๐๐ž๐Ÿ๐ข๐ง๐ž๐ฌ ๐ข๐ง๐ฃ๐ฎ๐ซ๐ฒ ๐ฌ๐ฉ๐ž๐œ๐ข๐Ÿ๐ข๐œ ๐ฆ๐ข๐œ๐ซ๐จ๐ž๐ง๐ฏ๐ข๐ซ๐จ๐ง๐ฆ๐ž๐ง๐ญ๐ฌ ๐š๐ง๐ ๐œ๐ž๐ฅ๐ฅ๐ฎ๐ฅ๐š๐ซ ๐ข๐ง๐ญ๐ž๐ซ๐š๐œ๐ญ๐ข๐จ๐ง๐ฌ ๐ข๐ง ๐ค๐ข๐๐ง๐ž๐ฒ ๐ซ๐ž๐ ๐ž๐ง๐ž๐ซ๐š๐ญ๐ข๐จ๐ง ๐š๐ง๐ ๐๐ข๐ฌ๐ž๐š๐ฌ๐ž ๐Ÿ‘‰ lnkd.in/gV4NmvwJ
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๐——๐—ถ๐—ด๐—ถ๐˜๐—ฎ๐—น ๐˜€๐—ฝ๐—ฎ๐˜๐—ถ๐—ฎ๐—น ๐—ฝ๐—ฟ๐—ผ๐—ณ๐—ถ๐—น๐—ถ๐—ป๐—ด ๐—ถ๐—ฑ๐—ฒ๐—ป๐˜๐—ถ๐—ณ๐—ถ๐—ฒ๐˜€ ๐˜๐—ต๐—ฒ ๐˜๐˜‚๐—บ๐—ผ๐—ฟ ๐—ฐ๐—ฒ๐—ป๐˜๐—ฒ๐—ฟ ๐—ฎ๐˜€ ๐—ฎ ๐˜๐—ผ๐—ฝ๐—ผ๐—น๐—ผ๐—ด๐—ถ๐—ฐ๐—ฎ๐—น ๐—ป๐—ถ๐—ฐ๐—ต๐—ฒ ๐—ถ๐—ป ๐—ฝ๐—ฟ๐—ผ๐˜€๐˜๐—ฎ๐˜๐—ฒ ๐—ฐ๐—ฎ๐—ป๐—ฐ๐—ฒ๐—ฟ ๐—ฐ๐—ต๐—ฎ๐—ฟ๐—ฎ๐—ฐ๐˜๐—ฒ๐—ฟ๐—ถ๐˜‡๐—ฒ๐—ฑ ๐—ฏ๐˜† ๐—ฎ๐—ป ๐˜‚๐—ฝ๐—ฟ๐—ฒ๐—ด๐˜‚๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐—ผ๐—ณ ๐—•๐—”๐—— โžก๏ธnature.com/articles/s41598-0โ€ฆโฌ…๏ธ
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๐— ๐—˜๐—ง๐—œ: ๐—ฑ๐—ฒ๐—ฒ๐—ฝ ๐—ฝ๐—ฟ๐—ผ๐—ณ๐—ถ๐—น๐—ถ๐—ป๐—ด ๐—ผ๐—ณ ๐˜๐˜‚๐—บ๐—ผ๐—ฟ ๐—ฒ๐—ฐ๐—ผ๐˜€๐˜†๐˜€๐˜๐—ฒ๐—บ๐˜€ ๐—ฏ๐˜† ๐—ถ๐—ป๐˜๐—ฒ๐—ด๐—ฟ๐—ฎ๐˜๐—ถ๐—ป๐—ด ๐—ฐ๐—ฒ๐—น๐—น ๐—บ๐—ผ๐—ฟ๐—ฝ๐—ต๐—ผ๐—น๐—ผ๐—ด๐˜† ๐—ฎ๐—ป๐—ฑ ๐˜€๐—ฝ๐—ฎ๐˜๐—ถ๐—ฎ๐—น ๐˜๐—ฟ๐—ฎ๐—ป๐˜€๐—ฐ๐—ฟ๐—ถ๐—ฝ๐˜๐—ผ๐—บ๐—ถ๐—ฐ๐˜€ nature.com/articles/s41467-0โ€ฆ #spatialtranscriptomics #TME #tumormicroenvironment #cellprofiling

METI: deep profiling of tumor ecosystems by integrating cell morphology and spatial transcriptomics

Nature Communications - Integrating tissue histology with spatial transcriptomics (ST) can significantly enhance the analysis of tumor heterogeneity and the tumor microenvironment (TME). Here, the...

nature.com
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๐—ง๐—ต๐—ฒ ๐—ฐ๐˜‚๐—ฟ๐—ฟ๐—ฒ๐—ป๐˜ ๐—น๐—ฎ๐—ป๐—ฑ๐˜€๐—ฐ๐—ฎ๐—ฝ๐—ฒ ๐—ผ๐—ณ ๐˜€๐—ฝ๐—ฎ๐˜๐—ถ๐—ฎ๐—น ๐—ฏ๐—ถ๐—ผ๐—บ๐—ฎ๐—ฟ๐—ธ๐—ฒ๐—ฟ๐˜€ ๐—ณ๐—ผ๐—ฟ ๐—ฝ๐—ฟ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐˜๐—ถ๐—ผ๐—ป ๐—ผ๐—ณ ๐—ฟ๐—ฒ๐˜€๐—ฝ๐—ผ๐—ป๐˜€๐—ฒ ๐˜๐—ผ ๐—ถ๐—บ๐—บ๐˜‚๐—ป๐—ฒ ๐—ฐ๐—ต๐—ฒ๐—ฐ๐—ธ๐—ฝ๐—ผ๐—ถ๐—ป๐˜ ๐—ถ๐—ป๐—ต๐—ถ๐—ฏ๐—ถ๐˜๐—ถ๐—ผ๐—ป nature.com/articles/s41698-0โ€ฆ)%20and%20microsatellite%20status.

The current landscape of spatial biomarkers for prediction of response to immune checkpoint...

npj Precision Oncology - The current landscape of spatial biomarkers for prediction of response to immune checkpoint inhibition

nature.com
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๐—ง๐—ต๐—ฒ ๐—ฐ๐˜‚๐—ฟ๐—ฟ๐—ฒ๐—ป๐˜ ๐—น๐—ฎ๐—ป๐—ฑ๐˜€๐—ฐ๐—ฎ๐—ฝ๐—ฒ ๐—ผ๐—ณ ๐˜€๐—ฝ๐—ฎ๐˜๐—ถ๐—ฎ๐—น ๐—ฏ๐—ถ๐—ผ๐—บ๐—ฎ๐—ฟ๐—ธ๐—ฒ๐—ฟ๐˜€ ๐—ณ๐—ผ๐—ฟ ๐—ฝ๐—ฟ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐˜๐—ถ๐—ผ๐—ป ๐—ผ๐—ณ ๐—ฟ๐—ฒ๐˜€๐—ฝ๐—ผ๐—ป๐˜€๐—ฒ ๐˜๐—ผ ๐—ถ๐—บ๐—บ๐˜‚๐—ป๐—ฒ ๐—ฐ๐—ต๐—ฒ๐—ฐ๐—ธ๐—ฝ๐—ผ๐—ถ๐—ป๐˜ ๐—ถ๐—ป๐—ต๐—ถ๐—ฏ๐—ถ๐˜๐—ถ๐—ผ๐—ป nature.com/articles/s41698-0โ€ฆ #biomarkers @nanostringtech @AkoyaBio @IntiZlobec @omichielin
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Integrating gene expression and imaging data across Visium capture areas with visiumStitched โ–ถ๏ธbiorxiv.org/content/10.1101/โ€ฆ โ—€๏ธ #SpatialTranscriptomics #visium @lcolladotor
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๐Ÿ‘@labs_mannDeep๐Ÿ‘ Visual Proteomics reveals DNA replication stress as a hallmark of Signet Ring Cell Carcinoma โฌ‡๏ธ biorxiv.org/content/10.1101/โ€ฆ
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What will spatial biology revolutionize next? Click here to select ๐Ÿ‘‰๐Ÿ‘‰๐Ÿ‘‰linkedin.com/feed/update/urnโ€ฆ ๐Ÿ‘ˆ๐Ÿ‘ˆ๐Ÿ‘ˆ #spatialbiology #spatialtranscriptomics #spatialproteomics #insitu #singlecell #tissue #FFPE
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