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Stahelin Lab (@Stahelin_Lab) profile picture

Stahelin Lab

@Stahelin_Lab

Laboratory at Purdue University using biochemistry and biophysics to study lipids and viruses. Drug development against viral hemorrhagic fevers. U2 fans!

 West Lafayette, IN
Joined April 2018
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Photo by Stahelin Lab (@Stahelin_Lab)Photo by Stahelin Lab (@Stahelin_Lab)Photo by Stahelin Lab (@Stahelin_Lab)Photo by Stahelin Lab (@Stahelin_Lab)Photo by Stahelin Lab (@Stahelin_Lab)Photo by Stahelin Lab (@Stahelin_Lab)Photo by Stahelin Lab (@Stahelin_Lab)Photo by Stahelin Lab (@Stahelin_Lab)Photo by Stahelin Lab (@Stahelin_Lab)Photo by Stahelin Lab (@Stahelin_Lab)
Check out our new preprint! biorxiv.org/content/10.1101/… We found sphingolipid binding to SARS-CoV-2 M protein controls its conformation to coordinate viral assembly+release. Great collaboration with @VothGroup + @Stahelin_Lab co-led by @KimDolan_UCB, Mandira Dutta, + @souadamiar.
Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly

Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly

M is the most abundant structural membrane protein in coronaviruses and is essential for the formation of infectious virus particles. SARS-CoV-2 M adopts two conformations, Mshort and Mlong, and...

biorxiv.org
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Abstracts Due 5/26!🌟 Explore the latest in #Phospholipid Biology at #LSHSRC! Join Antonella De Matteis @Tigem_Telethon and @VolkerHaucke in July for "Phospholipids in Aging and Disease." Topics: lipid signaling, treatments for diabetes, cancer, & more. bit.ly/3xQj5yp
For over 35 years, this Science Research Conference (SRC) has presented and integrated advances in phospholipid biology and signaling to foster new national and international collaborative projects. This year’s SRC will continue to encourage and support junior investigators, trainees, women, and minority scientists to pursue phospholipid biology research, ensuring that the study of human diseases relevant to aging remains vigorous. It will also accelerate the translation of fundamental advances into novel clinical treatments through the interactions of basic and clinical researchers. Presenters will explore all aspects of phospholipids, the major components of biological membranes, which play instrumental roles in guiding cell-to-cell communication and trafficking of nutrients and proteins.

ALT For over 35 years, this Science Research Conference (SRC) has presented and integrated advances in phospholipid biology and signaling to foster new national and international collaborative projects. This year’s SRC will continue to encourage and support junior investigators, trainees, women, and minority scientists to pursue phospholipid biology research, ensuring that the study of human diseases relevant to aging remains vigorous. It will also accelerate the translation of fundamental advances into novel clinical treatments through the interactions of basic and clinical researchers. Presenters will explore all aspects of phospholipids, the major components of biological membranes, which play instrumental roles in guiding cell-to-cell communication and trafficking of nutrients and proteins.

FASEB (@FASEBorg) profile pictureFASEB
@FASEBorg18 Apr 2024
4 amazing keynotes under one roof! Join @ghotamis and @JLS_Lab with organizers @OlzmannLab and @HenneLab for #LIPDSRC plus @AntonellaDeMat4 and @VolkerHaucke with organizers @BrookeEmerling and @sharontooze01 for #LSHSRC. Register for one to attend both: hubs.ly/Q02sPfRB0
Image from FASEB (@FASEBorg)
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It’s Dr. Emily David, Ph.D.! This degree was made possible by the incredible support from my family and friends, my mentor, @Stahelin_Lab and lab mates, @Purdue_MCMP dept., the @purduepharmacy, and @MbtpPurdue program. Boiler up! @LifeAtPurdue Photo by Chloe Smetanka
Image from Dr. Emily David (@emily_david_)
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We had a wonderful week at Madeira! Thank you all for the great discussions at the FEBS Special Meeting on Sphingolipid Biology. It was a pleasure to host you all! #sphingolipidbiology #SLBiol2023 #visitmadeira @FEBSnews @EMBOevents @CoskunPLID @BassereauTeam @Stahelin_Lab
Image from Liana C Silva Lab (@MolCellBiophys)
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New preprint online from the Stahelin lab and collaboration with the laboratory of Gregory Voth @VothGroup lead by Mandira Dutta. Anionic lipid interactions of the SARS-CoV-2 nucleoprotein! biorxiv.org/content/10.1101/…
The SARS-CoV-2 nucleoprotein associates with anionic lipid membranes

The SARS-CoV-2 nucleoprotein associates with anionic lipid membranes

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a lipid-enveloped virus that acquires its lipid bilayer from the host cell it infects. SARS-CoV-2 can spread from cell to cell or from...

biorxiv.org
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.@LifeAtPurdue just announced: 1) No increase to employee heath insurance premium, 2) $149M new residence hall, 3) $160M new building for nursing, pharmacy & One Health, 4) naming of @purdueglobal Law School, & 5) a new terminal at the Purdue Airport. purdue.edu/uns/PurdueToday/a…
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2 reflections of university as an engine for #economicgrowth: Greater Lafayette, home of @LifeAtPurdue’s main campus, ranked by @WSJ as the #1 emerging housing market in America, & Indiana ranked by @Forbes as the #1 state in America to start a #business. wsj.com/articles/indiana-and…
Indiana and Midwest Take Top Slots in WSJ/Realtor.com Housing Index

Indiana and Midwest Take Top Slots in WSJ/Realtor.com Housing Index

Lafayette, Ind., retained the top spot in the emerging home markets index for a third consecutive quarter.

wsj.com
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Another exciting talk about the importance of sphingolipids for viruses will be presented by Robert Stahelin @Stahelin_lab. Check the conference program at sphingolipidbiology2023.febs… #sphingolipids #lipidtime #visitmadeira @FEBSnews @FEBS_JS
Image from Sphingolipid Biology (@SL_Biology)
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Exciting update! Due to high demand, we've extended the early bird registration & travel award appl. deadlines! Don't miss out. Please RT. @FEBSnews @SL_Biology @MolCellBiophys @Gio_Dangel0 @hlatim @nadlerlab @HolthuisL @Stahelin_Lab @jlipidres @ASBMB sphingolipidbiology2023.febs…
Image from Fikadu G. Tafesse (@TheTafesseLab)
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Dr. Robert Stahelin, Retter Professor of Pharmacy and professor of medicinal chemistry and molecular pharmacology, is the 2023 Chaney Faculty Scholar. Congratulations! ow.ly/jUAE50OlZKj #pharmacysgiantleap
Image from Purdue Pharmacy (@purduepharmacy)
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Congratulations, @Stahelin_Lab !!
Purdue Pharmacy (@purduepharmacy) profile picturePurdue Pharmacy@purduepharmacy12 May 2023
Dr. Robert Stahelin, Retter Professor of Pharmacy and professor of medicinal chemistry and molecular pharmacology, is the 2023 Chaney Faculty Scholar. Congratulations! ow.ly/jUAE50OlZKj #pharmacysgiantleap
Image from Purdue Pharmacy (@purduepharmacy)
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A special joy is learning from fellow faculty colleagues at the Westwood Lectures at #Purdue. Today we had Professor Robert Stahelin, the Retter Professor in @purduepharmacy, discussing his excellent research on emerging virus pathogen.
Image from Purdue President (@PurduePresident)
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We are online! Visit sphingolipidbiology2023.febs… to know more about the upcoming FEBS Special Meeting on Sphingolipid Biology! @MolCellBiophys @Gio_Dangel0 @TheTafesseLab @FEBSnews @CoskunPLID @SchultzLabOHSU @NoemiJRojo @BassereauTeam
Image from Sphingolipid Biology (@SL_Biology)
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Great night celebrating the extraordinary career of Prof. Mark Cushman! 46 years at Purdue! #fantasticfaculty #pharmacysgiantleap
Image from Eric Barker (@DeanEricBarker)
Image from Eric Barker (@DeanEricBarker)
Image from Eric Barker (@DeanEricBarker)
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PIP-PIP-Hurray! Check out our work characterizing monophosphorylated phosphoinositides (PIP) isomers using gas-phase ion chemistry and dissociation kinetics in RSC Analyst by @KFabijanczuk pubs.rsc.org/en/content/arti…
Structural elucidation and isomeric differentiation/quantitation of monophosphorylated phosphoino...

Structural elucidation and isomeric differentiation/quantitation of monophosphorylated phosphoino...

Phosphoinositides, phosphorylated derivatives of phosphatidylinositols, are essential signaling phospholipids in all mammalian cellular membranes. With thr

pubs.rsc.org
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Electron tomography reveals four classes of cytopathic vesicles-II (CPV-II) stemming from the host Golgi apparatus following Venezuelan equine encephalitis virus infection. @Stahelin_Lab @RS_ebola @Purdue_MCMP life-science-alliance.org/co…
Image from LifeScienceAlliance (@LSAjournal)
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Join us at @LifeAtPurdue! We are seeking a tenure track #assistantprofessor in the field of Translational Neuroscience. Learn more and apply at careers.purdue.edu/job-invit…
Image from Purdue Borch MCMP (@Purdue_MCMP)
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Welcome to all new MCMP Graduate Students! Here’s to a great year in MCMP! (Picture: Emily David, PhD Grad in the @Stahelin_Lab)
Image from Purdue Borch MCMP (@Purdue_MCMP)
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Headed home after an incredible first FASEB #phospholipids meeting. Great week highlighted by hearing amazing science from an awesome group of people. Huge thank you to @Stahelin_Lab @KigerLabUCSD @BlindLab for organizing a super meeting
Image from Eamonn Dickson (@EamonnDickson)
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What a week @FASEBorg #phospholipid meeting! Congrats to the organizers @Stahelin_Lab @BlindLab @KigerLabUCSD & Isabel Merida (not on Twitter). It was great seeing old friends & making new ones! And having some fun- #lipidrafting. @JohnEBurke2 @airola_lab
Image from Fikadu G. Tafesse (@TheTafesseLab)
Image from Fikadu G. Tafesse (@TheTafesseLab)
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