@WChengLab

Biophysical and structural studies of ligand-gated ion channels. Lipid modulation. @WUSTL_AnesRsrch Washington University Department of Anesthesiology

 Washington University
chenglab.washu.edu
Joined August 2020
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Structural mechanism of lipid modulation of pentameric ligand-gated ion channel activity biorxiv.org/content/10.1101/… #biorxiv_biophys

Structural mechanism of lipid modulation of pentameric ligand-gated ion channel activity

Pentameric ligand-gated ion channels (pLGICs) are sensitive to the lipid environment. However, the structural mechanism of how specific lipids support the agonist response of any pLGIC is poorly...

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