Region 25: Lowellville Rockets (5-5) at Independence Blue Devils (6-4)

Region 25: Monroeville Eagles (5-4) at Dalton Bulldogs (4-6)

Region 25: Mathews Mustangs (6-4) at Ashtabula St John School Heralds (8-2)

Region 25: Norwalk St Paul Flyers (5-4) at East Canton Hornets (7-3)

Region 24: St Henry Redskins (7-3) at Madison-Plains Golden Eagles (8-1)

Region 24: Covington Buccs (7-3) at Huntington Huntsmen (7-3)

Region 24: St Bernard-Elmwood Place Titans (7-2) at Mechanicsburg Indians (8-2)

Region 24: Versailles Tigers (6-4) at Portsmouth West Senators (8-2)

Region 23: Newark Catholic Green Wave (7-3) at Fredericktown Freddies (8-2)

Region 23: Elgin Comets (8-2) at Garaway Pirates (7-3)

Region 23: Berne Union Rockets (7-3) at Waterford Wildcats (8-2)

Region 23: Centerburg Trojans (6-4) at Newcomerstown Trojans (8-2)

Region 22: Paulding Panthers (8-2) at Allen East Mustangs (7-3)

Region 22: Fairview Apaches (8-2) at Carey Blue Devils (6-4)

Region 22: Delta Panthers (7-3) at Seneca East Tigers (7-3)

Region 22: Patrick Henry Patriots (7-3) at Western Reserve Roughriders (10-0)

Region 21: Columbiana Clippers (8-2) at Brookfield Warriors (7-3)

Region 21: Grand Valley Mustangs (8-2) at Smithville Smithies (8-2)

Region 21: John F Kennedy Eagles (6-4) at United Golden Eagles (8-1)

Region 21: Wickliffe Blue Devils (8-2) at Mineral Ridge Rams (9-1)