UF MD/PhD. PhD Neuroscience. Neurobio/Neuroimmuno/Metabolism/Stress Biology. Artist formerly known as Dr. Love/Pre-Med Guy. 🤟.

80 Miles From Santa Fe
Joined January 2011
Suggesting that this makes Nick’s group looks better is clinical levels of delusion.
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I want to see an actual exposure number like yesterday.
BREAKING: "Speculative data center debt is being repackaged and sold to pension and retirement funds, university endowments, and other institutional investors in a manner eerily reminiscent of the subprime bubble," per AFR
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Credit to the trialists for a really good execution here, but not mentioning the intermittent fasting component was the only part designed to result in a caloric deficit is a bit of a hand wave, no?
New @Cell_Metabolism on benefit of intermittent fasting in overweight individuals with metabolic syndrome A randomized trial showed that the Mediterranean diet, while reducing lipid abnormalities, did not suppress inflammation until intermittent fasting was added cell.com/cell-metabolism/ful…
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Update no one ask for: I now officially hate the term ā€œprotocolsā€ on the modern era.
AI is trained on NPC doctor data It’s protocols suck and it’s way too risk averse to actually fix a complex issue Shit data in, shit protocols out
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ā€œAI cannot compress space and timeā€ is a pretty darn good line.
Replying to @ZKForTre
AI can only compress compute and language But it cannot compress space and time yet Labs haven't built the perfect RSI infra for biology yet
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It is… not great that they are just becoming familiar with lab timelines. Wait until they hear about clinical trial timelines.
Where do you go next after reporting from the Strait of Hormuz? For the past three months, Citrini Research, an independent research firm, has been working with our team and an internal research model to see if they could use AI to create a new drug. What follows is an entertaining, candid, and humbling account of a group of motivated nonexperts (or ā€œfilthy casualsā€, as Citrini would say) trying to tackle a real problem in human health with Claude. We landed on scorpion neurotoxins, which kill over 3,000 people a year. Of the 211 designs we produced and tested, 17 met our criteria for a binder. None of the designs bound more than one toxin and none have been tested for neutralizing a toxin. One of my favorite quotes from the piece is: ā€œOur virtual biologist may have compressed a year's worth of work into a couple days, but biology works at the speed of life…Over two days, we watched Claude work through problems at a speed that was difficult to comprehend. For the next two months, we spent much of the time becoming familiar with laboratory turnaround times (This mostly involved sending memes in Slack).ā€
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The thunder just adding Mara is madness.
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I don’t know a lot of residents that only work 65 hours per week, either.
I'm not saying residents should be paid like attendings. I'm saying the math deserves to be said out loud. $66,712 divided by roughly 3,380 hours a year is about $20 an hour, before taxes and before the student loans keep growing in the background. If you're in training right now: your income will change. Your habits won't unless you decide they will. What did your hourly rate work out to in residency? In training? My free live lecture series starts in January. Save your spot with the link in my bio.
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Rare day where I got some results/data that made me stand up from my chair.
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Frankly offensive levels of chart crime here
Limiting your salt intake is a very effective way to cause insulin resistance and boosting stress hormones.
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The term ā€œwokeā€ is now so diluted as to have lost any and all credibility, nuance, or value.
One of the worst woke decisions we ever made and I opposed it since day one
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Setting aside ā€œstudying actual medicine for a secondā€ — let’s not over-exacerbate how indicative of medical mastery differences even a started deviation level difference in grade or step1 score are. We are talking about 1 or 2 questions per test on highly biased question structures from reams of PowerPoint slides chosen by lecturers with motives that vary wildly on question selections that result in focusing on memorizing esoteric slide details over topic mastery. For step1 (which I’ve historically defended, and I’ll tell you my score if you care/think I’m biased), a 5 point difference is a couple of questions with unclear relevance to patient outcomes— is knowing lesch nyhan is an hprt1 mutation that impedes purine recycling or objectively challengable theoretical biochemistry questions (I took graduate biochemistry courses, suggesting single metabolites are definitely the right answer to hypothetical TCA manipulations is hilarious) predictive of clinical success? Further, is making most questions structured as frequentist statistical approaches over Bayesian ones in order to make the questions more arbitrary and therefore ā€œharderā€ helping make anyone a better clinician? Especially if it results in answering in such a way that you’d never be caught dead actually practicing on the clinic? Absolutely no chance. I know no one will real this, but I disagree with almost all the commentary here. Design med school to be mastery-based, increase the residency spots so the number of competitive seats grows, and let kids separate themselves on aggregate honest reviews, genuine clinical mastery, step1/2 scores on a more representative test, and substantive research output. Demand a more fair and less gameable framework, and the future doctors will rise to that level.
It was a huge mistake to eliminate Step-1 scores and grades in the first two years of med school. Say what you want, but grades & Step-1 scores focused students on studying actual medicine and they were fair. OK, I'll see myself out now.
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This account seems fun/cool but this is the absolute worst in grading behaviors and should be characterized as such. Bringing guac or bagels or whatever should be actively denigrated in grading as a likely grade bribe… I’m sure the kid who did it was totally competent, but the idea that residency fates are being decided by who brings in snacks is categorically absurd
Med student came in today with a massive container of homemade guac for us residents. It was so fucking good AND they gave us the recipe 100/10 on evals....plus he's way above his year in presentations and HPI
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I’m sick of people who don’t know what they are talking about blasting out commentary about clinical medicine
Re: Jalen Hurts, hematology is an incredibly specialized area of medicine in which every case and patient is very different. I would be very careful about staking any dynasty fantasy football decisions on things you read here, even from doctors. NFL players are, in general, a high-risk group for blood clots (higher BMI, lots of impact, lots of flying), and several have successfully returned to play after having them. Christian Barmore sacked Geno Smith yesterday, and Chris Olave is fantasy football's WR7 after having a pulmonary embolism last December.
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I love Pelissero in every way, but this is ridiculous today. Between the ā€œhow much does he love footballā€ and now the post-reporting mea culpa, this is journalism by tweet at its worst.
Just spoke to Jalen Hurts’ agent, Nicole Lynn, who clarified that while Hurts was up until early Sunday morning getting evaluated at a hospital, he was able to sleep upon rejoining the team and the Eagles set aside a room for him at the stadium. Videos from the stadium show Hurts coming onto the field just before kickoff and he felt rested enough to play.
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There is so much public and non-public info on insane medical and medical-adjacent malpractice (not even including the brain stuff) by nfl medical staffs and coaching staffs… idk how they get a pass for it all. I know it’s tough because players advocate to play a lot, but my goodness.
Jalen Hurts timeline is just organizational malpractice: - Finds out there’s a superficial blood clot while in London - Team doctors instruct him not to sleep - Jalen Hurts doesn’t sleep for 36 hours and then PLAYS in the London game - Blood clot moved locations - Jalen Hurts flies back to the US - He gets placed on blood thinners. And is now out for the season.
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Rare occasion where I genuinely hope someone is cosplaying as a doctor
This quoted post is unavailable.
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Really feel like this should be presented in context, as heart disease deaths at any given age have been going down (or are flat if we want to be pedantic about any and all age group)
Heart disease deaths are on the rise in the US
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