Mike Lodato (@_MikeLodato) header
Mike Lodato (@_MikeLodato) profile picture

Assistant Professor @UMassChan, father, husband, ex-jock. Owner of 100 billion mutant neurons, each with its own genome.

Worcester, MA
Joined February 2016
Photo by Mike Lodato (@_MikeLodato)Photo by Mike Lodato (@_MikeLodato)Photo by Mike Lodato (@_MikeLodato)
Harvard’s FAS is launching 25 tenure-track faculty searches, FAS Dean Hopi Hoekstra announced, loosening a hiring freeze instituted last spring as the school draws an influx of philanthropic support. @abbysgerstein and @amannmahajan report. thecrimson.com/article/2026/…
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Whitehead Institute Founding Member Rudolf Jaenisch has received the 2025 Ogawa-Yamanaka Stem Cell Prize, which recognizes his seminal role in establishing and advancing the field of induced pluripotent stem cells (iPSCs). wi.mit.edu/news/rudolf-jaeni… @GladstoneInst
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We are delighted to be a part of several exciting collaborative projects and are looking for a senior scientist to lead organoid generation and analysis for these projects, with room to develop independent projects as well. Please apply or share! recruit.apo.ucla.edu/JPF0979…
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Huge thanks to the Riccio fund and our fantastic collaborators in the Logan lab (@wickedneuro)!
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We’re hiring! We have an open position for a Research Associate in the Lodato lab, details here ummsjobs.com/job/10361/. It’s a great opportunity to gain skills at the bench, publish some papers, and learn about brain aging and somatic mutation. Please repost!
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We are entering the 7th year of our Next Generation Leaders (NGL) program! I have constantly been amazed by these NGLs - they are not only brilliant, creative scientists but also incredibly kind and genuine human being. Treasure the lasting bond with them! Hope you will join us!
Open call for Next Generation Leaders! Our NGL program recognizes early career scientists with fresh and innovative perspectives. For 3 years, NGLs contribute to ongoing research and initiatiatives at the Allen Institute. Apply by June 5: alleninstitute.org/about/peo…
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Mike Lodato retweeted
I'm delighted to share the latest work from our lab in which @HaoChingJiang1 and SungJin Park demonstrate that MS4A1/CD20 functions as a mammalian odorant receptor in a previously uncharacterized population of sensory neurons. rdcu.be/dE8B7
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Replying to @aaas @sudipsparikh
Very grateful to have been chosen as a AAAS fellow this year. Of course these awards are only possible due to the enormous efforts of the many grad students and postdocs that I have been lucky to mentor over the years. Let’s all have a drink😁
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Happy to share this review article on microglial phagocytosis mechanisms in development informing disease. Great collaborative effort between @becca_beiter and @patwsheehan in the lab. sciencedirect.com/science/ar…
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Mike Lodato retweeted
‼️Job alert! ‼️ multiple #postdoc positions open in my lab @Princeton. Interested in single cell #genomics & brain development? #studyBRAIN projects, cell type tools for 🐒🧠, weird evolutionary phenomena (chimeric microglia??) Check us out krienenlab.org & pls RT!
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📢 The Cai Lab is recruiting technicians! Neuroscience, computational, or psychology related experience is preferred. If you’re interested in joining our fun and talented team, please send an intro and CV to [email protected].
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Our work about contrasting patterns of somatic mutation accumulation between oligodendrocytes and neurons in the aging human brain, is now online in @CellCellPress! Huge thanks to @sarabiz86 @JoeLuquette @peter_j_park @ChrisAWalsh1. See tweetorial (1/10). tinyurl.com/4u9fj84r
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Amazing work from @zinan_zhou @junhokimkr @tuihuaorjinhua @EAliceLee2 @ClotildeLagier on mosaicism in ALS/FTD. How does a mosaic mutation in <5% of cells in one region produce pathologically conventional ALS/FTD? Answers welcome!
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Thanks @RealPatSargent and others in @UMassCommDept for highlighting our work and recent award from @ACS_Research. Very appreciative to our lab members and team @UMassChan who made this possible. We are hiring at all levels and excited to get started on this work!
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Turns out development of human cerebral cortex is unlike any animal ever described! Latest work from Sonia Nan Kim (@snk_kim) and twitterless Vinay Viswanadham @peter_j_park lab, using clonal mutations and cell types sampled across human cortex. biorxiv.org/content/10.1101/… A thread.
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Allenites are presenting 80+ posters at #SfN23! Check out the full list of posters: alleninstitute.org/events/sf… Topics include: 🧠 visual cortex 🧠 psychedelic drugs 🧠 aging 🧠 task-switching 🧠 cloud-based data processing 🧠 whole mouse brain atlases 🧠 brain clearing & expansion
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Taken together, gene expression changes in the aging brain influence and are influenced by the accumulation of somatic mutations during aging. 6/7
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I’m on my way to what looks like an incredible single cell genomics symposium hosted by @hopkinsmedicine, and then Ailsa and I will both be presenting this work at #SFN23 in D.C. next week. If you’re at either please find one of us to learn more! 7/7.
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