Applied Genomics (@appliedgenomics) header
Applied Genomics (@appliedgenomics) profile picture

Applied Genomics

@appliedgenomics

Directed by Hakon Hakonarson, the Center for Applied Genomics at CHOP leads genetic research into childhood diseases including asthma, autism, diabetes and IBD.

 Children’s Hosp. Philadelphia
caglab.org
Joined May 2010
  • Tweets1.3K
  • Following215
  • Followers1.1K
39Media
Photo by Applied Genomics (@appliedgenomics)Photo by Applied Genomics (@appliedgenomics)Photo by Applied Genomics (@appliedgenomics)Photo by Applied Genomics (@appliedgenomics)Photo by Applied Genomics (@appliedgenomics)Photo by Applied Genomics (@appliedgenomics)Photo by Applied Genomics (@appliedgenomics)Photo by Applied Genomics (@appliedgenomics)Photo by Applied Genomics (@appliedgenomics)Photo by Applied Genomics (@appliedgenomics)
We’re looking at how a report that contains information about genetic risk for some health conditions may help you and your providers make choices about your health. Enrolling ages 3-75. More info: [email protected] youtu.be/G9L-iadq0DE
The eMERGE study at CHOP: what it’s about and why you might want to join

The eMERGE study at CHOP: what it’s about and why you might want to join

This video explains the eMERGE study, including what it’s about and...

youtube.com
1
1
CAG's Chris Cardinale and Hakon Hakonarson new studies on genetics and autoimmunity: Elevated Levels of Cytokine LIGHT in Pediatric Crohn's: doi: 10.4049/jimmunol.2200652 GWAS of age of onset T1 diabetes reveals HTATIP2 as a novel T cell regulator: doi: 10.3389/fimmu.2023.1101488
101
CAG's paper "NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients" received 2,903 downloads since its publication in @NatureComms! Access the article here: nature.com/articles/s41467-0….
NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients

NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients

Nature Communications - HCCAA is a dominantly inherited disease which causes brain hemorrhages as a result of mutant cystatin C aggregation in carriers. Here, the authors show that n- acetyl...

nature.com
nih.gov/news-events/news-rel…

Researchers wirelessly record human brain activity during normal life activities

NIH BRAIN Initiative-funded study opens the door to correlating deep brain activity and behavior.

nih.gov
Nice paper from folks at U of Colorado: Admixed Populations Improve Power for Variant Discovery and Portability in Genome-wide Association Studies biorxiv.org/content/10.1101/…
Admixed Populations Improve Power for Variant Discovery and Portability in Genome-wide Association...

Admixed Populations Improve Power for Variant Discovery and Portability in Genome-wide Association...

Genome-wide association studies (GWAS) are primarily conducted in single-ancestry settings. The low transferability of results has limited our understanding of human genetic architecture across a...

biorxiv.org
1
23andMe goes public in deal with Richard Branson theguardian.com/technology/2…
Fears over DNA privacy as 23andMe goes public in deal with Richard Branson

Fears over DNA privacy as 23andMe goes public in deal with Richard Branson

Genetic testing company with 10 million customers’ data has ‘huge cybersecurity implications’

theguardian.com
CHOP researchers reverse severe lymphatic disorder in patient with Noonan syndrome: eurekalert.org/pub_releases/…
2
2
Interesting Case Study from @TheLancet Genomic evidence for reinfection with SARS-CoV-2: a case study: thelancet.com/journals/lanin…
Image from Applied Genomics (@appliedgenomics)
Researchers from Children's Hospital of Philadelphia (CHOP) have shown there may be key genetic differences in the causes of attention-deficit hyperactivity disorder (ADHD) between African Americans and people of European ancestry: prn.to/32W8qAf

ADHD Study Reveals Unique Genetic Differences in African American Patients with the Condition

/PRNewswire/ -- Researchers from Children's Hospital of Philadelphia (CHOP) have shown there may be key genetic differences in the causes of attention-deficit...

prnewswire.com
Nice write-up by @nsf on our group's use of deep learning to predict sites of DNA methylation and identify therapeutic targets: nsf.gov/discoveries/disc_sum…
1
Our friends at @CHOP_Research put together a nice write-up about our Minority-Enriched Genomics Program, which will focus on health outcomes in (primarily) African Americans: research.chop.edu/cornerston…
Delighted to announce our eMERGE Enhanced Diversity program has been awarded! We will use genomics to improve risk assessment for diverse populations and integrate the findings into clinical care! @IngoHelbig @lab_hill @suefurth_chop @RebeckaPeebles chop.edu/news/chop-s-center-…
1
We are very excited to be part of the next phase of eMERGE! The awards were announced today, and privileged to be among such great company: genome.gov/news/news-release…
Image from Applied Genomics (@appliedgenomics)
1
Researchers reveal important genetic mechanism behind inflammatory bowel disease bit.ly/39TCeNZ via @chop_research @EurekAlert
2
1
nature.com/articles/s41588-0…
We are neck-and-neck in the #STATMadness contest highlighting the most innovative research of the year! Please support CHOP research and @ChildrensPhila by clicking here: statnews.com/feature/stat-ma…
1
3
Over 100,000 votes have been cast, and we are through to Round 2 of #STATMadness ... learn about and support CHOP research here: statnews.com/feature/stat-ma…
1
Click on the @childrensphila logo to vote for CAG in STAT Madness 2020! statnews.com/feature/stat-ma… via @statnews (@CHOP_Research)
1
3
We were DELIGHTED to be chosen by @statnews in this year's #STATMadness - a bracket-style competition to honor the best biomedical research published in 2019! ... statnews.com/2020/02/24/stat…
1
Load more