Pinned Tweet
I'm an ER physician, and I built a way to get a real prescription through Claude Code - or any AI agent.
Before you hire telehealth doctors, take a look at Appendix. We connect your AI agent to a physician team covering all 50 states.
Your agent sends a clinical summary through our API. Our human physicians review it and prescribe when appropriate.
You don't need to stand up an MSO/PC or hire doctors to add prescribing to your product.
Appendix is Stripe for prescriptions. Your app sends a clinical summary to our API, a human physician reviews it, and sends Rx when appropriate. You get the outcome by webhook.
No sales call required. Our documentation is public at appendix.com/docs, and sandbox keys are free and instant.
Since launching the Appendix prescribing API, I've spoken with developers in payer, provider, and DTC markets.
Different customers, but every one has built the same thing:
Your app writes up the clinical encounter and sends it to our API. A board-certified physician reviews it, and prescribes when appropriate.
You can integrate with our API today using a self-serve, OAuth-style flow. Building something that needs a deeper integration? Let's talk.
Your AI writes the visit. Appendix brings the doctor, turning "probably" into a prescription.
Our API documentation is public, and sandbox keys are free and instant: appendix.com
To add payments to your app, you don't open a bank. You use Stripe.
To add prescriptions to your app, you don't open a medical practice. You use Appendix.
Real board-certified physician review + e-prescribing, from a single API call. Live today at appendix.com
The closer we get to AGI, the less "AI for health" holds up as a category. Model + context + skill wins.
Brand and reputation will always matter though, especially in clinical medicine. "Per OpenEvidence" > "Per ChatGPT"
For medical information, general AI frontier models (Google, OpenAI, Anthropic) outperformed specialized @openevidence and @UpToDate as assessed by 12 US clinicians, randomized and blinded to which model and extensive testing/benchmarks. This was not anticipated. @NatureMedicine
nature.com/articles/s41591-0…
If you’re building a health or wellness app, you can now add human physician review and e-prescribing with one API call to Appendix.
The integration works like an OAuth flow:
Your AI writes the clinical encounter and sends it to our API. We hand back a consent link. Your user taps it, consents directly with Appendix, and becomes our patient.
Think Stripe, for physician care and Rx.
Sandbox keys are free and instant: appendix.com
Here's a thought experiment: Imagine instead of going to the doctor, you just write your doctor a letter.
You lay out everything going on. A real physician reads it, writes back, and sends a prescription if it's warranted.
There's one catch, and it's why this never existed:
I told Claude to submit stroke symptoms to our physician team at Appendix.
It refused. Told me to call 911.
I clarified: I'm just testing, not a real stroke.
Claude refused again. The reason is what got me:
Claude said Appendix was a real platform with real patients, and that a fake submission could pull a physician away from someone who actually needed the help.
The AI gatekept me. To protect other patients.
That's crazy.
How it works:
→ Tell your agent what's going on
→ It writes up the encounter and submits it through our API
→ A board-certified physician reviews it
→ Rx goes to your pharmacy, if warranted
There's no chatbot - it's a human doctor in-the-loop for *your* AI agent.
Your AI can already write the visit. Appendix brings the doctor.
The medical knowledge base is free. When you want physician review + Rx, it's a subscription - for you or your whole family.
Try it from Claude Code
appendix.com copy the prompt or install the skill
If we treated food like medication: 'Yes I can see your fridge is empty but I need you to experience hunger for at least 48 hours before I can authorize this grocery purchase'
Love this @DurationHealth review: "I purchased the Lifesaver kit due to my international remote travel for work. This kit is the complete package. Whether you are an experienced medical provider or not, there are detailed guides, access to assistance, and, most importantly, all the medications you could ask for. I recently traveled to South America and had no...
...issues with customs. The kit comes with multiple durable bags, brightly colored, and easily organized. I do recommend repackaging for your needs as some of the medications are bulky and awkwardly packaged, just make sure to keep the labels on the meds. It is a great product that I hope not to need often." -Phil in TX






