Prof. Petr Broz lab @unil Innate Immunity Host-pathogen interaction #inflammasome #celldeath Account run by lab members. RT is not endorsement.

Lausanne, Switzerland
Joined April 2019
We’re happy to share our updated manuscript on Ninj1, incorporating measurements of membrane tension, cellular assays of ninj1 and ninj2 dimer stability and MD simulations of ninj1 oligmers opening and forming (see below!). biorxiv.org/content/10.1101/…
3
17
1,599
We're thrilled to share the lab's latest publication demonstrating how caspase-4 and the non canonical inflammasome recognize cytosolic LPS by preferentially binding to the convex portions of membranes - both bacterial and micelles @ImmunityCP @DIB_UNIL sciencedirect.com/science/ar…
1
9
1
23
2,730
Finally, we show that increased membrane curvature makes more sites for caspase4 to bind, which we observe with immunogold/TEM and MD simulations, thanks to key contributions from @MasarykUni
1
1
139
Congratulations to Jakub who led this project and all authors for their contributions.
1
105
With the Ambizone award comes a webpage for my new group @DIB_UNIL!! I’m thrilled to be officially starting in January 2026. 🥂 unil.ch/fbm/en/home/menuinst…
1
4
6
943
Congratulations to (former!) postdoc @EHartenian on launching her career with a prestigious SNF Ambizione grant at the @DIB_UNIL studying how hosts respond to viral infection in her own lab here at University of Lausanne.
3
16
934
Check out the lab’s latest review on ninj1 biology by @EBernard1993 and @EHartenian. Your one stop shop for all ninj1-related questions 😉@CurrentBiology cell.com/current-biology/abs…
2
4
1
31
1,655
Thanks to authors of the news and views for @AlexandraBoegli 's NLRP6 story, highlighting the disruption to homeostasis as the activation trigger. link.springer.com/article/10…
2
2
15
1,558
November is a big month for the lab with *two* new papers by @EHartenian and @AlexandraBoegli ++ co authors now online. embopress.org/doi/full/10.10… link.springer.com/article/10…
1
12
3,434
Postdoc opportunity in @jourdainlab !
We are hiring a postdoc! 🧪 ▶️ Project: nucleotide metabolism (genomics & biochemistry) ▶️ Start date: spring 2026 (flexible) ▶️ More info and application: tinyurl.com/3kjrbb2x Please share 🌏 @DIB_UNIL @unil @snsf_ch
2
1
669
It’s DIB day! The annual conference for our department @DIB_UNIL. It’s a lovely day (and view!) at the Lausanne Olympic museum exchanging with our colleagues. Plus a stellar presentation on NINJ1 by our own @EBernard1993 🔬!
1
9
426
2nd day of the PRR kicks off with more great talks from all speakers including our own Jakub Began. @DIB_UNIL @Immunobiology22
1
14
658
Kicking off the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors organized by our department in Lausanne! @broz_lab @fabiomartinon @RebsamenLab @FBM_UNIL
5
24
1,861
🚨 Abstract submission deadline: July 15th 2025🚨 Do not miss the opportunity to present your research: 10 selected short talks and an exciting poster session! Register and submit your abstract here: wp.unil.ch/immunobiologysymp…
We are excited to announce the 2nd edition of the Symposium on the Immunobiology of Pattern Recognition Receptors, October 1-2, 2025, Lausanne, Switzerland🇨🇭! Attendance is limited to 150 participants. Registration and info: wp.unil.ch/immunobiologysymp… @DIB_UNIL
2
6
772
Congratulations to Doctor Alexandra Boegli who very successfully defended her PhD on Listeria activation of NLRP6 through induction of lysosomal damage 🥳!! Very well deserved (and a very well enjoyed celebration) 🥂
1
1
35
1,097
Join us in Lausanne October 1-2 for the 2nd edition of the Symposium on the Immunobiology of Pattern Recognition Receptors with an exciting line up of invited speakers! Registrations are open and attendance is limited to 150 participants: wp.unil.ch/immunobiologysymp…
We are excited to announce the 2nd edition of the Symposium on the Immunobiology of Pattern Recognition Receptors, October 1-2, 2025, Lausanne, Switzerland🇨🇭! Attendance is limited to 150 participants. Registration and info: wp.unil.ch/immunobiologysymp… @DIB_UNIL
3
5
1,111