Infectious Diseases Physician
Brisbane, Queensland
Joined August 2017
- Tweets244
- Following719
- Followers425
- Likes1.4K
Please take a few moments to complete the survey below on casual inference
📣 Calling all causal inference users!
👋 Hello #IDTwitter, #EpiTwitter, #CausalInfer, I am conducting a survey as part of my PhD studies and I need your help! 🎓🔬
🌐📝 Please take a few moments to complete the survey by clicking on the following link:
uniofqueensland.syd1.qualtri…
Our paper on cefiderocol susceptibility of carbapenm resistant klebsiella isolates is out!
Higher rates of cefiderocol resistance among NDM producing Klebsiella bloodstream isolates applying EUCAST over CLSI breakpoints - wish there could be some better agreement on this ! @burcucella tandfonline.com/doi/full/10.…
Well done @Hendonet
From the micro working group of @snap_trial @DrToddLee @Josh_S_Davis @syctong
🆕️⚡️#JAC Multi-site, international laboratory study to assess the performance of penicillin susceptibility testing of Staphylococcus aureus #IDTwitter academic.oup.com/jac/advance…
3
442
Antifungal susceptibilities of Aspergillus sp from QLD, AU link.springer.com/article/10…
More isolates with ⬆️ voriconzaole MIC values in 2020-21. No difference in azole resistance between North QLD vs Southeast QLD acquisition 🇦🇺@burcucella @peter_simos
4
467
Can we do model informed dosing for vori in QLD? @jasonroberts_pk
Traditional voriconazole TDM only has PTA 47-67% - can MIPD help us optimize antifungal dosing? #eccmid23 #ECCMID2023 Spriet & @CornelyOliver
1
1
555
80% of NDM producing Klebsiella was CDRO-R using EUCAST breakpoints.
Nice to see @burcucella @AbdullahTarikA1 presenting their poster on high rates of cefiderocol resistance in NDM Klebsiella from Turkey - and the differences between CLSI vs EUCAST breakpoints ! @UQMedicine #ECCMID2023
3
355
There is a humanitarian crisis in #TurkeyEarthquake. Please consider donating
British Red Cross donate.redcross.org.uk/appea…
Unicef unicef.org.uk/donate/syria-t…
Turkish search& rescue ass. akut.org.tr/en/donation
Dutch red cross doneer.rodekruis.nl/aardbevi…
CRAB BSI. Source ?septic hip (native). Amp-sul R. What is your abx choice?@ABsteward @DrToddLee @IdVilchez @drtimothyli @davidlye70 @BradSpellberg @padstamundo @Josh_S_Davis @Cortes_Penfield @davidantibiotic
38%Cefiderocol
20%Colistin
33%Trim-sulfa
9%Other (explain)
284 votes • Final results80 year old CA-SAB. ? Skin source (skin excision at GP, but no overt SSTI). BC sterile after 48h, TTE NAD, and he is well. But he has an ICD<1 year old. Would #IDtwitter request a TOE to rule out ICD infn? @DrToddLee @DrEmilyMcD @BradSpellberg @ABsteward @IdVilchez @LBaddour1
63%Yes, always
22%No, not necessary
16%Depends (pls explain)
315 votes • Final resultsThanks everyone! Here is the answer of "JACC Cardiovascular Imaging Expert Panel":
pubmed.ncbi.nlm.nih.gov/3492… @drtimothyli
1
2
Would anyone treat gram neg liver abscess with po amoxi+/-clav? Biliary source, multiple abscesses, panS Ecoli in blood, cipro and bactrim cannot be given #IDtwitter @DrToddLee @BradSpellberg @IdVilchez @ABsteward
#IDtwitter Chronic DFO for conservative management (=no debridement). How long do you treat? 6 vs 12?
1
Severe legionella longbeachae pneumoniae. Still febrile and MV on day 5 of azithro. Chest drain placed. What would #IDTwitter do?
27%Continue azithro
34%Switch to FQ
14%Other (pls explain)
25%Show the results
44 votes • Final results 2
5
Great thread from @adm_stewart summarizing the MERINO-2 results with key take home messages.
The recently published MERINO-2 trial in OFID is a pilot clinical trial which compares the use of piptaz to mero for treatment of bacteremia due to AmpC-producers. Correct interpretation of data and take-home messages are of great importance 1/
2
2
"COVID-19 and its risks will be with us for at least another year or two. We need health advice and interventions to be consistent, predictable and sustainable"
My views on how in Australia, with still little Covid transmission, good contact tracing and quarantining etc, is an effective and successful approach despite the dire predictions of some.
Lockdown demands were wrong: Sydney shows how to fight COVID-19 smh.com.au/national/nsw/lock…
1
Our review paper on Achromobacter is out!
Brilliant review by @burcucella on treatment options for Achromobacter infections @padstamundo @davidantibiotic @UQMedicine aac.asm.org/content/early/20…
Exposure to polymyxins, rather than in-hospital transmission, leads to the development of PR in K. pneumoniae.
Emergence of Polymyxin Resistance in Clinical Klebsiella pneumoniae Through Diverse Genetic Adaptations: A Genomic, Retrospective Cohort Study academic.oup.com/cid/advance…
Found this "encyclopedia" from 1994 on the shelves of State Library of Queensland. Life of an ID doc must have been much easier few decades ago.
Piperacillin-avibactam active against MDR Burkholderia cepacia complex and and Burkholderia gladioli isolates.
jcm.asm.org/content/early/20…
5
Colistin resistance rate was 62.3% among THREAT isolates and most NDM (86%) was coproduced with OXA-48, which is quite worrying.#ECCMID2019
#ECCMID2019 @burcucella NDM coproduction with OXA-48 increasingly seen but colistin resistance may be 30% or higher...