We're interested in the relationship between gene activity and phenotypic outcomes after challenges like genetic mutations, chromatin disruption and infection.
Cambridge, England
Joined June 2019
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Someone on Mastodon recently posted about issues they've seen with #zebrafish annotation in recent #Ensembl versions, so we wrote down some of what we've noticed.
The TL;DR version is that we are just using Ensembl 109's annotation, including for enrichment analyses.
Busch Lab retweeted
Today is a very exciting day to see this paper finally published in @NatureGenet 💫
Congratulations to Ana Topf and Volker Straub for the hard work and the resilience 👩🔬 🔬 👨🔬
@jwmdrc @UniofNewcastle @anatopf
Enjoy the reading nature.com/articles/s41588-0…
Busch Lab retweeted
It was such a pleasure to give an interview for the First Person series @DMM_Journal!
This is a great space for researchers to highlight their science and plans for the future.
doi.org/10.1242/dmm.050683
Busch Lab retweeted
The final version of our new article is out @DMM_Journal! We analysed the transcriptome of Shigella flexneri infection in zebrafish larvae and discovered Shigella-inducible factors involved in controlling host susceptibility.
doi.org/10.1242/dmm.050431
Busch Lab retweeted
New article out! We analysed the transcriptional signature of Shigella flexneri infection in zebrafish larvae and discovered Shigella-inducible factors involved in controlling host susceptibility.
Thanks to all the co-authors!
doi.org/10.1242/dmm.050431
Busch Lab retweeted
Wave if you've enjoyed your week of #bioinformatics training 👋!
Thank you to the participants, trainers, and organisers at 'Introduction to RNA-seq and functional interpretation'. We look forward to seeing what you do next.
Discover more training: ebi.ac.uk/training/
ALT A group of smiling people are looking up at a camera and waving. You can see scientific posters and red walls behind them. The overlaid text says: Introduction to RNA-seq and functional interpretation. EMBL-EBI course | 20 – 24 February 2023. The EMBL-EBI logo is also displayed. Photo credit: Sophie Spencer, EMBL-EBI, 2023.
Busch Lab retweeted
Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to Shigella flexneri biorxiv.org/cgi/content/shor… #bioRxiv
Busch Lab retweeted
👋 Thank you to all the trainers, organisers, and delegates for joining us for our last on-site course of the year! @e_m_busch, @mirloupa, @aleenamolbio, @Antonia_Nilsson, @iansealy, @richysix, @canicamxli, and many more.
➡️Join us at an event in 2023: ebi.ac.uk/training/live-even…
ALT Bioinformatics and functional genomics in zebrafish. EMBL-EBI course | 27 – 30 September 2022. A group of people look up to a camera, smile, and wave.
Busch Lab retweeted
Do you have a cool idea for a genetic screen in #zebrafish or are you interested in robustness during development? Get in touch to discuss this #postdoc fellowship call rea.ec.europa.eu/funding-and… @QMUL @QM_SBBS
If you were thinking of registering but haven't had time then we have good news - you've now got until next Friday. Come and join us as we return to the lovely Wellcome Genome Campus for four days of zebrafish bioinformatics and functional genomics.
For one week only, we've extended the deadline for our #zebrafish course due to popular demand!
🗣️ @busch_lab, @e_m_busch, @BENsembl, @ensembl, @canicamxli, @news4go, @reactome, @ExpressionAtlas
🔗Apply by 8 July: ebi.ac.uk/training/events/bi…
Busch Lab retweeted
For one week only, we've extended the deadline for our #zebrafish course due to popular demand!
🗣️ @busch_lab, @e_m_busch, @BENsembl, @ensembl, @canicamxli, @news4go, @reactome, @ExpressionAtlas
🔗Apply by 8 July: ebi.ac.uk/training/events/bi…
One week left to apply for our #bioinformatics and functional #genomics in #zebrafish course that will be held at @emblebi this September. 🦓🐟
🔗 Apply now: ebi.ac.uk/training/events/bi…
We couldn't be at #IZFC2022 this year, but hope to meet some #zebrafish researchers @emblebi in September. There's a week left to apply.
One week left to apply for our #bioinformatics and functional #genomics in #zebrafish course that will be held at @emblebi this September. 🦓🐟
🔗 Apply now: ebi.ac.uk/training/events/bi…
Busch Lab retweeted
Big thanks for the ongoing support from @stevewilsonfish and @The_MRC, and to all our collaborators @fishymusings @leovaldevo @ibianco3 @NeuhaussLab @CorinneHouart @realRihellab!
Come and join us! Please spread the word.
🦓🐟Applications are open!
Learn how to design functional #genomics experiments, manage and analyse #RNAseq datasets from #zebrafish, and compare results to other species.
🗣️ @e_m_busch, @iansealy, @richysix, @canicamxli & more
🔗 Apply by 1 July: ebi.ac.uk/training/events/bi…
ALT An image of a zebrafish is overlaid with the text 'Bioinformatics and functional genomics in zebrafish. 27-30 September 2022. EMBL-EBI Hinxton, United Kingdom. The EMBL-EBI logo is in the bottom right of the screen.
Please share this open PhD position in our lab: "Investigating the rules of paralogue interactions during embryonic development"
We have an open PhD position, please share! Closing date 22nd March, do get in touch with any questions. qmul.ac.uk/sbbs/postgraduate…
Busch Lab retweeted
Super happy to have this story up @biorxivpreprint with @stevewilsonlab. Allele-specific expression can mess with your mutant #RNAseq, always check genomic location of DE genes! #zebrafish
A red herring in zebrafish genetics: allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants biorxiv.org/cgi/content/shor… #bioRxiv
Busch Lab retweeted
A red herring in zebrafish genetics: allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants biorxiv.org/cgi/content/shor… #bioRxiv
Busch Lab retweeted
Thanks NIDA for the opportunity to present to the 2021 GECCRT meeting! Look for #Leggieri #Mech #Hosseinian & #Merteroglu to access our works tinyurl.com/2021GECCRT
@Dan10R3r10 @aleksandra_mech @saEdehosseinian @busch_lab