Iasi, Romania
Joined February 2007
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27 new legal regimes? No thanks. Europe needs ONE real, clean digital-first standard entity. #EUINC eu-in.org/cta @euinc_petition
claudiu florea retweeted
Serb students are cleaning the graphitis and cleaning up their city
They are calling this “real patriotism”
Current situation.
So, basically, 500 million Europeans expect 300 million Americans to protect them from 120 million Russians who can’t even defeat 40 million Ukrainians while those 500 million Europeans don’t even realize they are being conquered by 2 billion Muslims who claim they are being persecuted by 8 million Israelis. Is that about right?
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claudiu florea retweeted
We will enter an age of abundance
If we can stop the communists for the next 5 years
claudiu florea retweeted
this might be my last normal tweet before biotech goes vertical
i'm not a whistleblower. I don't work at Lilly, Novo or any of the big labs
but there is a massive shift happening in human biology right now.
it's sitting in press releases and almost nobody reads them
the last 6 months alone:
- a once-daily pill roughly doubled median survival in metastatic pancreatic cancer (13.2 vs 6.6 months)
- a one-time gene editing infusion cut hereditary angioedema attacks 87%, and 62% of patients stayed attack-free and off all other prevention for 6 months
- a one-time gene edit for cholesterol dropped LDL up to 62%, and it held for over a year
- a personalized mrna vaccine beat keytruda alone in a 1,137 patient melanoma phase 3
- retatrutide hit ~28% weight loss in a phase 3
- an ai-designed drug entered phase 3
- a pill that regrows hair passed its second phase 3
- an immunotherapy that could let some rectal cancer patients skip surgery, chemo and radiation just got fda approved
- a man lived 271 days off dialysis on a pig kidney
- human cells were caught passing chromosome-sized chunks of DNA to their neighbors, and it changes how the neighbors behave
we are on the verge of an era where the human body is a software problem and the update cycle gets shorter everyday
stick around, it's going to get weird
bio/acc
claudiu florea retweeted
Harry Kane going from football’s most famous trophyless player to a Ballon d’Or winner might be the greatest example of why changing employers can improve your life.
claudiu florea retweeted
“Barack Obama is one of those people who are often wrong but never in doubt.”
— Thomas Sowell
claudiu florea retweeted
🚨 BREAKING: SpaceX locked Anthropic into paying them $3.1 billion per MONTH for compute starting December
$37B a year
= $120.5 BILLION through 2029
Every month, ~80% of Anthropic's current revenue would be SpaceXSI compute bill
BIGGER than its Google and Amazon long-term deals
Anthropic warns short-term compute "carries a higher cost per unit" and will "compress our operating margin"
claudiu florea retweeted
In Italia ci sono 300.000 cinesi, 170.000 indiani, 153.000 filippini e 350.000 sudamericani. Nessuno di questi ha difficoltà di adattamento. Nessuno di questi va in piazza a sfasciare le vetrine.
claudiu florea retweeted
If high taxes and a big welfare state worked, France would be a utopia. The citizens would be dancing on the streets… instead they are the civil unrest capital of Europe.
On the flip side, Switzerland with its low tax, small state is peaceful, calm, affluent and secure.
Good Intentions don’t matter. Good outcomes do.
claudiu florea retweeted
Milton Friedman: “Keep your eye on one thing and one thing only: how much government is spending, because that’s the true tax.”
“If you’re not paying for it in the form of explicit taxes, you’re paying for it indirectly in the form of inflation or borrowing.”
claudiu florea retweeted
The problem isn’t that AI is intelligent. It isn’t. The problem is that too many adults (but not all) are at once mechanistic, imitative, unimaginative, stupid, formulaic, influenceable, & gullible, arrogant beyond their skill set, & too expensive to maintain.
claudiu florea retweeted
The intellectual case for socialism ended in 1920.
Somehow, more than 100 years and 100 million lives later, these terrible ideas still persist in our society.
As a species, humans are not as smart as we sometimes make ourselves out to be.
Ludwig von Mises sat down in 1920 and published a paper that ended the intellectual case for socialism, even if the socialists took another seven decades to notice.
The argument was precise. Mises showed that without private ownership of the means of production, there are no real prices for capital goods. Without prices, you cannot calculate profit and loss. Without profit and loss, economic planners have no way of knowing whether they are creating value or destroying it. They are flying blind, spending real resources with no feedback mechanism telling them whether the factory, the railway, or the grain depot was worth building. Every allocation becomes a guess dressed up as a decree.
This, he called the Socialist Calculation Problem, and nobody answered it. Oskar Lange tried in 1936, proposing that socialist planners could simulate prices by trial and error. Mises read this and was unimpressed (charitably put). Lange assumed you could reproduce the function of market prices without the institution that generates them: private property, genuine exchange, real skin in the game. You cannot fake the signal and expect accurate information.
The Soviet Union spent seventy years proving Mises right. Chronic shortages, misallocated steel, surplus winter boots in Georgia in July, famine engineered by committees convinced they understood grain supply better than the price system. The USSR collapsed in 1991 under the weight of precisely the inefficiencies Mises predicted in Vienna in 1920.
You are watching this play out again today, every time a government sets energy prices, rent ceilings, or pharmaceutical price caps, and then expresses shock at the resulting shortages. The calculation problem did not expire with the Soviet Union. Bureaucrats who override price signals recreate the same blindness Mises identified. Mises told you exactly what would happen.
