entrepreneur, founder Om, founder of 1859, inc. — love intersection of AI and techbio — prefer to build.
San Diego, CA
Joined June 2009
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1/ 🧪 @Xaira_Thera put a robot arm on its HPLC and let its agent run the handoffs. over seven days it moved and analyzed 18 plates of proteins, 80% more than a modeled 9-to-5 loading schedule. 👇
5/ 📊 related: same week, @warpsciences launched with $215M to build a US chemistry CRO where chemists start the work and robots take over repetitive steps like reaction setup and purification. businesswire.com/news/home/2…
6/ ✅ the writeup: xaira.com/news/x-automate-br…
for people running protein production: which instrument in your pipeline sits idle overnight the longest, and what would you need to see before letting a camera-guided arm load it?
1/ 🧪 clinical data on an AI-discovered drug at @myESMO: @iambic_ai's HER2 inhibitor IAM1363 had partial responses in 19 of 53 patients with targetable HER2 changes dosed at 960 mg or more (36%). confirmed so far: 23%. most patients were heavily pretreated. 👇
5/ 📊 related: @InSilicoMeds says rentosertib, its generative-AI-enabled drug for IPF, has entered phase III. this week it also hit a first milestone in its servier oncology deal, worth up to $888M. prnewswire.com/news-releases…
6/ ✅ the ESMO 2026 poster (FPN 1072P): cdn.prod.website-files.com/6…
for oncologists treating HER2+ breast cancer after T-DXd and tucatinib: what confirmed intracranial response rate would make you refer a patient to this trial?
5/ 📊 related: two days earlier BMS signed with @boltz_bio to run boltz's models on its own DGX SuperPOD and co-develop custom models. that's two AI deals for BMS in one week, one in molecular design and one in clinical development. boltz.com/bms-partnership
6/ ✅ the financing: pathos.com/pathos-ai-secures…
for clinical development teams: short of running trials with and without it, what evidence would convince you an AI system improved a trial's design?
1/ 🧬 the UK is setting up an AI biosecurity lab: £100M of government money, plus up to £200M in model credits and access from @OpenAI and @AnthropicAI. the government calls it the world's first organisation dedicated to AI biosecurity. 👇
5/ 📊 related: earlier this month @biohub, the US DOE and NIH, plus meta, google deepmind and isomorphic labs, committed $1.8B to open, AI-ready biological data for models that predict how cells respond. biohub.org/news/virtual-biol…
6/ ✅ the announcement: gov.uk/government/news/intro…
for people working on biosurveillance or countermeasures: what's the one capability a lab like this should ship in its first year to show it's useful?
