Hon Weng Chong (@dr1337) header
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MD, Entrepreneur, Tinkerer - Founder of Cortical Labs and CliniCloud | Forbes 30u30 | Tweets represent my personal views.

Melbourne, Victoria
Joined November 2008
Photo by Hon Weng Chong (@dr1337)Photo by Hon Weng Chong (@dr1337)Photo by Hon Weng Chong (@dr1337)Photo by Hon Weng Chong (@dr1337)Photo by Hon Weng Chong (@dr1337)Photo by Hon Weng Chong (@dr1337)
After seven years, I’ve resigned from Cortical Labs. I’m proud of what we built, and grateful to everyone who was part of the journey — from an ambitious idea to something very real. It’s been an extraordinary chapter. I no longer have access to my Cortical Labs email, so if you’d like to stay in touch, please feel free to DM me here. Onwards and upwards.
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100% agree - it is not a foregone conclusion that scaling LLMs and their ilk will solve all biomedical problems and capital is unfortunately a zero-sum game. Capital going into same pool of ideas is less capital going to plurality of ideas and possible outcomes.
Replying to @DeryaTR_
I am 100% rooting FOR this, and trying to accelerate it as fast as I possibly can in my own limited capacities. As an investor, part of my job is to try and put probabilities on highly uncertain scenarios, and timing is often the hardest element. And of course limited financial and Human Resources need to be applied to activities of different risk levels. We could put everyone and all the money on moonshots, which if they pay off change everything, but that would be to the detriment of less risky near term wins that could have immediate impact for patients. What the world IS doing is a little of both, and I think the market is probably right about the ratio, or a bit underweight on the moonshots but not radically off.
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Hon Weng Chong retweeted
When Demis Hassabis talks about curing all diseases within 10 years, @dawallach says scientists who have spent decades studying these problems aren't necessarily buying it. "When [scientists] hear AI people say smart things, they go, 'Cool, yeah, let's run it.' Everyone respects Demis." "But when Demis says we're gonna cure all diseases in 10 years, I think people who have two PhDs and have been doing this for 40 years go, 'Come on, man.'" "You're giving a sort of false hope to a lot of people who are legitimately out there suffering or have a loved one who's on death's doorstep. That's a little messed up."
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Hon Weng Chong retweeted
Turns out voters hated the loud, giant expensive warehouses that demand cities' worth of power built explicitly to enrich the already-rich and powerful
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Hon Weng Chong retweeted
silicon valley spent a lot of time telling people they would be the “permanent underclass,” their jobs are fake, they’re dumb for worrying about data centers, and also they might end the world. probably should’ve spent a bit more time on what’s possible instead tbh
silicon valley spent so much time trying to explain what ai will make possible for ppl. but it deeply underestimated how many ppl are primarily fearful of what ai will take away from them.
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Hon Weng Chong retweeted
they’re calling it a bluekkake
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Hon Weng Chong retweeted
So regime change in Texas before Tehran
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Every AI CEO reminding themselves that they care about inequality and ESG starting tomorrow
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I just want to congratulate these guys on going all in on Trump.
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Waiting for the chameleons to abandon the term SI and return back to AI.
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Hon Weng Chong retweeted
Curious to have watched numerous non-invasive “mind-reading, brain solving(?)” BCIs get funded, yet it’s unclear to me what has fundamentally been solved technologically that unlocks this capability. This is especially perplexing in EEG which categorically has very poor SNR and compliance challenges. I hope to be enlightened…
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Hon Weng Chong retweeted
Anyone who thinks the following simple model: y = f(dot(X, W) + B) where X = input vector, W = weight matrix, f() = differentiable nonlinear activation for gradient backpropagation captures the full complexity of real neurons needs to go back to school & learn the difference.
Trying to locate the spark.
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Hon Weng Chong retweeted
The latest hot thing from Silicon Valley: Unfalsifiability! Stop participating in annoying debates that revolve around pesky inconveniences like “logic” or “truth”… Instead, try the millenia old playbook of religious authority! Declare yourself part of a gnostic priesthood, with insights only you and select few have the ability or anointing to see. Cosy up to the executive authority who have the guns and prisons in exchange for your money and blessing and conferred legitimacy. Make threats to conform under penalty of unemployment or social ostracism. Promise forms of eternal damnation (permanent underclass) for differential thinking. Assume everyone else is too stupid to understand why we should change the basis of society because of your spurious and fragile multiplications of tiny probabilities; especially over time horizons filled with infinite correlations and interactions that can’t possibly be accounted for. Have no other life experiences nor give yourself time to understand nuance or love or pain or sex or culture. Note that it’s particularly important to spend all your time in front of an approved laptop with the approved apps in an approved faux-designer space, with all your accessories from influencers chasing the same kind of faux, engineered emptiness. When you do go out, go to a converted warehouse to do Hyrox or CrossFit. Whatever you do, don’t let sunlight touch your skin. Essential: Never say anything testable. Never use deduction. Never consider your preconceptions. There is nothing new under the sun. Whatever can be tested, must be tested.
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Hon Weng Chong retweeted
"Computational simulations generally lack the causal powers and intrinsic properties of the things being simulated. A simulation of the digestive system does not actually digest anything. A simulation of a rainstorm does not make anything actually wet. If we simulate a living creature, we have not created life. In general, a computational simulation of X does not bring X into being — does not instantiate X — unless X is a computational process (specifically, an algorithm) itself. Making the point from the other direction, the fact that X can be simulated computationally does not justify the conclusion that X is itself computational. In most cases, the distinction between simulation and instantiation is obvious and uncontroversial. It should be obvious and uncontroversial for consciousness, too. A computational simulation of the brain (and body), however detailed it may be, will only give rise to consciousness if consciousness is a matter of computation. In other words, the prospect of instantiating consciousness through some kind of whole-brain emulation, at some arbitrarily high level of detail, already assumes that computational functionalism is true. But as I have argued, this assumption is likely wrong and certainly should not be accepted axiomatically. This brings us back to the poverty of the brain-as-computer metaphor. If you think that everything that matters about brains can be captured by abstract neural networks, then it’s natural to think that simulating the brain on a digital computer will instantiate all its properties, including consciousness, since in this case, everything that matters is, by assumption, algorithmic. This is the “Turing world” view of the brain." noemamag.com/the-mythology-o…
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Hon Weng Chong retweeted
Ironic… Surely the ATO can just absorb the costs like a small business is 🤷‍♀️🫠🫠
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today on x dot com
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Would love to know how AU Gov would have responded to if instead of OpenAI, a Chinese model hacked Medicare.
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Made it in Time
TIME’s new cover: Announcing the 2026 TIME100 AI, the world's most influential people in artificial intelligence time.com/collection/time100-…
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TIME’s new cover: Announcing the 2026 TIME100 AI, the world's most influential people in artificial intelligence time.com/collection/time100-…
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if you’re a white person going to China people will be obsessed with you if you’re an ABC going to China they will just think you’re retarded because you can’t speak Mandarin
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