EPFL Life Sciences

A study led by the laboratory of Andrea Ablasser has mapped how thousands of genetic changes affect a protein central to immunity, inflammation, cancer, and rare immune diseases. actu.epfl.ch/news/mapping-th…

🦠 Scientists from EPFL show that cholera bacteria can exchange protective genes, including antiviral immune systems, when they live in aquatic environments. The finding helps explain how these pathogens survive viral attacks and evolve in marine habitats. actu.epfl.ch/news/how-choler…

Researchers at EPFL have discovered how oxygen-sensing explains why amphibians regenerate limbs and mammals do not. actu.epfl.ch/news/when-oxyge…

Researchers at EPFL, Heidelberg University and Roche have built a human mini-bladder to show how urine composition weakens bladder tissue, helping infections recur even after antibiotics. go.epfl.ch/4b354f

New preclinical models for invasive lobular carcinoma have enabled the testing of a promising new drug that effectively slows tumor growth by targeting key features of the disease - opening the door to future clinical trials. go.epfl.ch/fd2a98

Can neurons be rejuvenated to restore memory? Our scientists show that switching on three “reprogramming” genes in a very small group of memory-related neurons restored memory in aged mice and in mouse models of Alzheimer’s disease. go.epfl.ch/71bfb4

🐻 Scientists from our university and Alaska Pacific University has developed an AI program that can recognize individual bears in the wild, despite the substantial changes that occur in their appearance over the summer season. go.epfl.ch/d8e2b4

Neural interfaces are the winners of the 2026 Queen Elisabeth Prize for Engineering. Nine scientists are honoured, including J.Bloch and G.Courtine (EPF/UNIL/CHUV,) recognized for their development of electronic spinal stimulation technology. actu.epfl.ch/news/neuroscien…

🧪 A new liver- and gut-targeted oral drug has shown, in a first clinical trial, its ability to reduce triglycerides and other blood lipids - major risk factors for cardiovascular disease, stroke, and pancreatitis. go.epfl.ch/502f54

Our scientists have identified a molecular pathway that protects cells from lipid oxidation and ferroptosis, a regulated form of cell death involved in aging and several diseases. go.epfl.ch/fa3d89

🧪 Our researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy. go.epfl.ch/d969ad

How do cells help keep their protein levels steady even when their ability to make new proteins changes? A new study could shed light on how our bodies stay resilient when nutrients and other resources rise and fall. go.epfl.ch/29edf2

Crucial discovery from @EPFL & @JohnsHopkins: Enzyme KMT2D, a key epigenetic regulator in #ProstateCancer, offers a new therapeutic target. Potential for more effective treatments against resistant tumors. actu.epfl.ch/news/cracking-t…

Our scientists have created a scalable 3D organoid model that captures key features of early limb development, revealing how a specialized signaling center shapes both cell identity and tissue organization. go.epfl.ch/e2d74e

The Swiss Laboratory Animal Science Association awarded on Wednesday its 2025 Prize to neuroscientist Mackenzie Mathis, Professor at EPFL, “for her outstanding contribution to the refinement of animal research.”  go.epfl.ch/6689f9

A team of researchers from our University uncovers how charge and structure control ion flow in biological nanopores, paving the way for new biosensors and ion-based computing. actu.epfl.ch/news/nanopores-…

Flipping an “epigenetic switch” on a single gene can turn memories on and off. EPFL scientists used #CRISPR tools to precisely control memory expression in mice, a first in the field. This could pave the way for new approaches to memory-related disorders. actu.epfl.ch/news/switching-…

A new computational method developed at EPFL, @unil and @CHUVLausanne creates synthetic receptors to boost T cells against solid tumors. These "T-SenSERs" sense the tumor environment and convert inhibitory signals into activating ones. #immunotherapy actu.epfl.ch/news/custom-des…

Congratulations to professor Andrea Ablasser, who has been named a Clarivate Citation Laureate in Physiology or Medicine in recognition of her pioneering contributions to innate immunity. go.epfl.ch/1cad91

🧠 Our researchers developed a powerful method to generate brain-wide, biologically realistic wiring maps of the mouse brain. Their approach bridges experimental data with mathematical & computational modeling to simulate how neurons connect. go.epfl.ch/477a74