The Ewald Lab studies chronic inflammation & innate immunity with the parasite Toxoplasma
UVa Charlottesville, VA
Joined May 2017
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Excited to share our new story explaining how macrophages use nitric oxide derivatives to shut down Toxoplasma evasion of cell-autonomous immunity. Congrats to @zhaoxyu6 and the team! link.springer.com/10.1038/s4…
Excited to share our new review discussing how host-pathogen interactions can be explored with spatial proteomics and transcriptomic tools. There should be something for virologists, bacteriologists & parasitologists in here!
@samy_lempke journals.asm.org/doi/full/10…
Congratulations to my wonderful @UVABIMS student @nadi_immunology and the new class @HHMINEWS #GilliamFellows! Honored and excited to bring insights from this creative community of scientists and DEI advocates back to @UVASOM & @DiversityUVASOM
2 Immunology Faculty positions are now open in the Carter Immunology Center at the University of Virginia: 1 Assistant and 1 Associate/Full Professor. Come join a terrific & collaborative scientific community nestled in the Shenandoah. DM with questions. Please retweet!
A heartbreaking loss. I was so fortunate to have benefited Nilabh’s thoughtful scientific advice and generous support at each stage of my career- as grad student down the hall and as a Toxo immunologist starting a lab- he is missed.
So sad we have lost legendary immunologist Nilabh Shastri. He was my next door neighbor and mentor. Can’t think of a more brilliant, kind, generous human being. It was such a privilege to be his friend and colleague at Hopkins for the much too short amount of time he was here.
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A blueprint for better equity and inclusion practices in graduate science edu by UVa trainees. Read! Get involved!
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Check ⬇️ when considering seminar speaker invitations
It's Follow-Friday! Connect with us and spread the word. We are a global collective of Black immunologists and allies. We are organizing and planning #BlackInImmunoWeek(Nov 22-28). We are also developing #BlackInImmunoHub, a network to connect/diversify #Immunology research field
This is a great department that first turned me on to immunology research as an undergrad. Apply!
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@thebrookenapier @AnnaCliffe1 @seemaychou @tajieharris @BlandLabUVA @sepiddsh @RutkowskiLab @RauchLab @ClareHardingLab @lenapernas 10 more women scientists with new and growing labs! Who else have we got?
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Our latest paper shows that IL-1 signaling promotes metabolic tissue fibrosis in Toxoplasma infection-induced cachexia. Congrats @sjmelchor and our wonderful Barker lab collaborators @DanAbebayehu disq.us/t/3ruopko
How stringent a bottleneck is the BBB for Toxoplasma infection? What a surprising result! So much fun to help address this question with an awesome new @labratorychild tool!
Proud to share the preprint of our work where we barcode Toxoplasma with a novel CRISPR-based approach and then investigate the host brain colonization bottleneck!
biorxiv.org/content/10.1101/…
Inspiring collaboration with @ewald_lab and @FrickelLab, with @ceirej leading the work
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@uva_bims trainees & faculty- want to support diversity in our science community? Our colleagues are hosting @PictureaSciFilm screening & discussion.
Sign up here: docs.google.com/forms/d/e/1F…
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The Ewald Lab is hiring!
1) R35 funded post doc position to study cachexia of parasite infection.
2) Lab technician to develop STOMP collaborations.
We are committed to supporting a diverse and vibrant research environment please apply via the link below or DM for more info!
Post Doc position: uva.wd1.myworkdayjobs.com/UV…
Research Tech position:
uva.wd1.myworkdayjobs.com/UV…
Congratulations to @sjmelchor and our wonderful collaborators who discovered that chronic activation of the IL1 pathway during parasite infection makes the host sicker by promoting the muscle wasting Cachexia jimmunol.org/content/204/12/…
Our paper using Automated Spatially Targeted Optical Micro Proteomics (AutoSTOMP) to identify Toxoplasma proteins and parasite vacuole membrane proteins is live! Congratulations to Bocheng, Harry and our excellent collaborators!
pubs.acs.org/doi/10.1021/acs…
A Macrophage Colony-Stimulating Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence cell.com/immunity/abstract/S…
Proud to pre-published in BioRxiv this week. We found a new way to study the fatal loss of muscle that occurs in chronic disease. Big thx to the awesome team!
Toxoplasma gondii infection triggers chronic cachexia and sustained commensal dysbiosis in mice biorxiv.org/content/early/20…