Improving patient care through the use of gene, cell and nucleotide therapies. #GeneTherapy #CellTherapy #CRISPRTherapeutics #GeneticEngineering @SinaiGenetics
New York
Joined June 2012
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Icahn Genomics Institute retweeted
Thrilled to see a new paper led by the outstanding @Brown_lab1, now out in Nature Biotechnology.
We provide mechanistic insights into how mRNA vaccines work. challenging key assumptions and offering new ways to control vaccine activity. (1/3)
Read here: nature.com/articles/s41587-0…
Few places left for the FREE online 🎓International Immunoschool🎓 Join IGI Director Brian Brown & other immunologists Mar 10-12 for an exclusive deep dive into the cutting-edge research behind successful immunotherapies and what's on the horizon:
SIGN UP eventbrite.com/e/internation…
Icahn Genomics Institute retweeted
Immunology will be for everyone, everywhere, everyday, from driving foundational research to reaping the benefits for health.
🌎 Immunoschool 2025 is open for all looking to learn about key immunotherapy advances over the last decade.
FREE TO REGISTER: eventbrite.com/e/internation…
Icahn Genomics Institute retweeted
First lab tweet! Sharing new papers:
PRINT Using Perturb-map, we show how ovarian tumors resist immunotherapy loom.ly/eHXDm4w
PREPRINT Developed new technology to easily generate cell-targeted LNP-RNA @SantagataMDPhD @JoshuaBrodyMD @yizhoudonglab
Icahn Genomics Institute retweeted
📄 NEW PAPER 📈 in @NatureMedicine from @DiegoChowell introducing 🦂 SCORPIO 🦂, a machine learning tool that predicts who will benefit from checkpoint inhibitor immunotherapy—using only routine clinical blood tests! loom.ly/412Y4WY
To find out how genetic immune escape alterations interact with environmental factors in cancer, and understanding this relationship informs approaches to early detection and therapy, check out this REVIEW in @trendscancer by @diegochowell & @fran_mj88 >>> cell.com/trends/cancer/fullt…
Icahn Genomics Institute retweeted
Blood–brain barrier-crossing conjugates (BCC). Exciting collaboration with the teams @EricJNestler @aw_charney @Ramon_Parsons # Xiaolin Cheng! Thanks @NatureBiotech editors and reviewers, @IcahnMountSinai @IcahnInstitute @SinaiImmunol @SinaiBrain @TischCancer @BMEIIsinai
Intravenous administration of blood–brain barrier-crossing conjugates facilitate biomacromolecule transport into central nervous system go.nature.com/412exBi
Icahn Genomics Institute retweeted
I am mobilizing + giving free weekly science communication workshops in a private community for scientists who want to join the battle vs misinformation. I wasn't planning on doing this so soon but this is urgent. We need you. Scientists, DM with your credentials for details.
📰PAPER @CellCellPress from IGI Director Brian Brown shows how ovarian cancers evolve local neighborhood control and use IL-4 to resist anti-PD-1 immunotherapy. The findings support a key role for type 2 immunity in cancer and the possibility of drugging this pathway for therapy.
Discovering IL-4's role in ovarian cancer was made possible with Perturb-map spatial functional genomics and great collaborations between @Brown_lab1 Baccarini lab @MiriamMerad @sorger_peter and @SantagataLab @DmitriyZamarin and @ChiaraFalcomata @JiaRenLin @Nelson_LaMarche.
Icahn Genomics Institute retweeted
Alison Goate's groundbreaking work in 1991 helped identify the "London mutation" in the APP gene. Her discovery illuminated how this mutation promotes amyloid-β aggregation, advancing our understanding of the genetic factors behind #Alzheimers pathogenesis nature.com/articles/d41586-0…
Life sciences are buzzing uptown, with a robust and open network of new lab spaces for industry and academia, and programs from @SinaiImmunol and @IcahnInstitute to introduce high school students in Harlem and the Bronx to biomedical research, MORE INFO ⤵️ nypost.com/2024/10/06/lifest…
Icahn Genomics Institute retweeted
Thinking about a PhD in immunology?
Join @jeremiahfaith1 and @KamphorstAlice OCT 9 at 4PM to ask all your Qs about our Multidisciplinary Research into the Immune System immunology graduate training program.
WEBINAR SIGN UP >>> visit.icahngraduate.org/even…
Icahn Genomics Institute retweeted
Please join us. :)
Please join us! Mon. 10/7/24 | 5-6:30pm EDT via zoom. A community event for individuals w- #DownSyndrome & families @EmmaGuttman & @BogunovicLab will discuss Skin Diseases & an upcoming clinical trial. To register: downsyndromeclinicaltrial.co… @IcahnMountSinai
Icahn Genomics Institute retweeted
Graphic novel shows unconventional routes into science
Stories of people's unconventional routes to becoming scientists are told in a new graphic novel intended to encourage others into the field.
bbc.co.uk/news/articles/c3e9…
Icahn Genomics Institute retweeted
Join the Next Generation Immunotherapy Discoveries symposium on innate immunology & more, online and in-person in NYC on Oct. 3rd! Hosted by @SinaiImmunol & @InnatePharma, online registration is FREE, with limited in-person seats available.
Learn more at innate-symposium.com!
We are delighted to welcome @igen_lab_mssm to the IGI! Find out more about his cutting-edge research on metallo-immunotherapy and more here >>> igen-lab.com/
Icahn Genomics Institute retweeted
Check out our recent perspective in Nature Biomedical Engineering on Metalloimmunotherapy—a promising new approach to immunotherapy that leverages the immune-modulating properties of metal ions to modulate various immune processes and treat diseases.
nature.com/articles/s41551-0…
Icahn Genomics Institute retweeted
🚨 New paper🚨 in @BCD_AACR! Thrilled to announce our study: MM Risk & Outcomes Associated with Pathogenic Germline Variants (PGVs) in DNA Repair Genes: bit.ly/4e2F70R. Main findings and key implications 🧵 (1/)
#MMsm #MultipleMyeloma #Myeloma #BloodCancerAwarenessMonth
#OnlineFirst: Multiple Myeloma Risk and Outcomes are Associated with Pathogenic Germline Variation in DNA Repair Genes. bit.ly/4e2F70R
#MMsm #CancerGenomics
