RNA discovery biology, platform development, gene therapy. Former worm wrangler and neuroscientist. Mid-pack marathon/ultrarunner.
Boston, MA
Joined July 2010
- Tweets427
- Following232
- Followers158
- Likes358
Ian McLachlan retweeted
Congratulations to Steve Flavell and 3 others @MIT on being named @HHMINews Investigators! Flavell’s lab studies neural mechanisms underlying internal brain states (e.g. different motivational and arousal states). picower.mit.edu/news/hhmi-ho… @mitbrainandcog @ScienceMIT #neuroscience
This quoted post is unavailable.
Ian McLachlan retweeted
Not to be a crankypuss, but awarding a Nobel for work that suffered from not being taken seriously for decades only *after* it proved to be of incredible value is not a triumph of prizemaking - it's a complete condemnation of it and the entire culture of modern academic science.
An email from @mountain_goats asks "does the future hold a series of four two-song 7"s called the SUBTYPES OF VOLTAGE-GATED SODIUM CHANNELS QUARTET?" and I respond, as a neuroscientist, WELL, I REALLY HOPE THAT IT DOES
3
1,150
Ian McLachlan retweeted
The lab's latest is out 👏🏽👏🏽 Congrats in particular to first author @TravistyzAside and co-authors and collaborators @alison_marie1 @imclach @_MikeOD_ and (I think twitter-free) Steve Flavell. Linking previous tweetorial below.
academic.oup.com/genetics/ad…
Ian McLachlan retweeted
Post docs*
*sound ON 🔊
xitter.gq/KiwiEV/status/15413006…
Ian McLachlan retweeted
I am excited to announce that I will be opening a laboratory in the Cell Biology Department @EmoryMedicine this coming winter! We will study signal processing in the somatosensory system using mouse genetic tools, electrophysiology, and imaging.
Ian McLachlan retweeted
Congress must pass legislation that codifies Roe v. Wade as the law of the land in this country NOW. And if there aren’t 60 votes in the Senate to do it, and there are not, we must end the filibuster to pass it with 50 votes.
getting tired of all this smack talk about Tiktaalik when everyone knows the real problem child was Australopithecus.
The meme crowd yearns to thwack Tiktaalik with a rolled-up newspaper or poke it with a stick — anything to shoo it back into the water and avoid our having to go to work and pay rent nyti.ms/3KBRstF
Ian McLachlan retweeted
Behavior changes depending on whether you are happy, hungry, stressed
In C. elegans, these all affect olfaction - and in so many different ways!
Modulation of a single neuron involves synapses, peptides, TOR signaling etc...to tune receptor expression
biorxiv.org/content/10.1101/…
New preprint from the Flavell Lab! How are multiple internal states encoded and integrated in neural circuits? We asked the worm and found that its chemoreceptor repertoire changes with state, directly impacting the animal's sensorimotor behaviors. (1/8) biorxiv.org/content/10.1101/…
Together, we find a single sensory neuron integrates multiple states and stimuli to generate a meaningful sensorimotor response to reflect the animal's overall state. Integrated transcriptional changes at the periphery may be a general mechanism to drive adaptive behaviors. (7/8)
1
1
Big thanks to @TalyaKramer and Malvika Dua (soon to be a @PiN_Harvard student!) here in Steve Flavell's lab at @MIT_Picower for their help, along with our collaborator @WpiJagan and his student Liz DiLoreto. (8/8)
2
Ian McLachlan retweeted
25 years ago my contemporaries promised me that when they had tenure, lots of funding and an established lab they would help change things. Now that they do, they're playing by the rules "for their trainees", who promise to change things when they have tenure, lots of funding...
This quoted post is unavailable.
