馃КSMARCA4 inactivation (SWI/SNF). This case: TP53 p.V274A, TMB 12.6
鈽笍Right pleural-based masses and plaques with effusion on CT; FDG-avid on PET/CT (SUVmax 14.3)
馃КHER2 overexpression in up to ~90% of cases
鈽笍MRI: enhancement and thickening of the nipple-areolar complex, with retroareolar or segmental non-mass enhancement.
馃Кt(X;18) SS18::SSX1/2/4 fusion
鈽笍Well-circumscribed intramuscular mass with heterogeneous enhancement on contrast-enhanced MRI (representative case)
鈽笍Round high-density mass on mammography; circumscribed hypoechoic mass with blood flow on US (this case)
猸昅edullary thyroid carcinoma
馃敩Nests of monotonous polygonal to plasmacytoid cells in a hyalinized stroma
馃КRET or RAS driver mutations, mutually exclusive in sporadic cases; germline RET in MEN2A/2B
猸旸uctal adenocarcinoma of the prostate
馃敩Papillary and cribriform glands lined by tall columnar pseudostratified epithelium
馃И尾-catenin+ (focal nuclear)
馃КAPC mutation with loss of heterozygosity (this case)