David Lagman (@lanternshark) profile picture

David Lagman

@lanternshark

Evolutionary biologist interested in the role of gene duplications in evolution of novel features, particularly in chordates.

 Uppsala, Sweden
Joined February 2011
  • Tweets611
  • Following192
  • Followers71
37Media
Photo by David Lagman (@lanternshark)Photo by David Lagman (@lanternshark)Photo by David Lagman (@lanternshark)Photo by David Lagman (@lanternshark)Photo by David Lagman (@lanternshark)Photo by David Lagman (@lanternshark)Photo by David Lagman (@lanternshark)Photo by David Lagman (@lanternshark)Photo by David Lagman (@lanternshark)
How did vertebrate opsins 👁️diversify? - putting the last pieces of the puzzle together Gene linkage in a jawless vertebrate living in a distant corner of the world shed light on a big evolutionary picture of the light-sensing ☀ system we all rely on. academic.oup.com/mbe/article…
Image from Tree-thinkers Lab✨自然派ゲノム研究室 (@KurakuLabMSM)
6
12
905
#DBfeature #Oikopleura🌊 Pax3/7 gene function in Oikopleura dioica supports a neuroepithelial-like origin for its house-making Fol territory by David Lagman, Daniel Chourrout et al @lanternshark sciencedirect.com/science/ar…
House phenotypes in homozygous pax37B mutant animals

ALT House phenotypes in homozygous pax37B mutant animals

3
5
648
Loving deep-sea fish and molecular evolution? We're hiring!:-) Looking for a motivated PhD student to join us to study evolution of vision & to explore limits of vertebrate eye in extreme environment. Deadline 15th March. Thanks for applying and sharing! fishevo.com/erc-funded-phd-p…
Image from Zuzana Musilova - FISHEVO 🇺🇦🇺🇦🇺🇦 (@zuzmus)
37
2
102
10,270
I am more than happy to share our preprint about the evolution of non-visual and visual opsins in fishes, fruit of a collaboration between the Salzburger lab (@fogg_lily , @WSalzburger ) and Fabio Cortesi (@FCortesi). biorxiv.org/content/10.1101/…
Evolution of the non-visual and visual opsin gene repertoire in ray-finned fishes

Evolution of the non-visual and visual opsin gene repertoire in ray-finned fishes

Photoreception – the detection of light for image formation (vision) as well as for non-image-forming purposes (circadian regulation, DNA repair) – is critical to the survival of most animals. In...

biorxiv.org
1
7
11
965
✨Read how a team of researchers led by David Lagman @lanternshark uncovered how #Oikopleura dioica repurposed ancient cellular machinery to build its complex, food-filtering "house." @AppyGenetics @mchlab @UiB @SocDevBio ⬇️ uib.no/en/michaelsarscentre/…
6
12
801
✨Huge congratulations to David Lagman @lanternshark with Anthony Leon @Bio_Antho, Nadia Cieminska @nadia24075483, Wei Deng, Marios Chatzigeorgiou @mchlab, Simon Henriet, and Daniel Chourrout @AppyGenetics for their latest publication in Developmental Biology @SocDevBio! 👏 @UiB
Chourrout lab (@AppyGenetics) profile pictureChourrout lab@AppyGenetics30 Aug 2024
We are so happy to see @lanternshark's work finally published! By using a wide set of techniques (CRISPR, scRNA-seq, ISH, FISH, IF), we show the importance of Pax3/7b+ cells in the formation of the house in O. dioica. Moreover ...🧵 check 👉 doi.org/10.1016/j.ydbio.2024…
5
13
1,210
We are so happy to see @lanternshark's work finally published! By using a wide set of techniques (CRISPR, scRNA-seq, ISH, FISH, IF), we show the importance of Pax3/7b+ cells in the formation of the house in O. dioica. Moreover ...🧵 check 👉 doi.org/10.1016/j.ydbio.2024…
1
6
2
21
2,640
Finally! The work I did during my postdoc Bergen @MSarsCentre in the @AppyGenetics lab out in Developmental Biology! Great job everyone involved! doi.org/10.1016/j.ydbio.2024…
2
3
1
18
1,507
Feel free to visit my poster P057 at #EED2024. The work was done in collaboration with @lanternshark at @MSarsCentre. Peace out ✌️
Image from Antho Leon 🇵🇪 (@Bio_Antho)
1
5
1
27
2,141
New preprint from the lab: biorxiv.org/content/10.1101/… . @ZonglaiL @HoyerJorgen show that members of the evolutionarily conserved #Anoctamin superfamily modulate Ciona metamorphosis rates in response to mechanical & chemical inputs. @UiB @MSarsCentre
1
7
2
26
2,115
Our lab engineer @Bio_Antho had the opportunity to show his results on scRNAseq analysis of O. dioica. His collaboration w/ @lanternshark at @MSarsCentre is helping our team to investigate the origin and divergence of lineage-specific cell types in larvaceans @OISTedu @UiB
Image from Chourrout lab (@AppyGenetics)
1
2
15
521
Our engineer @aaasjord has been in charge of the appendicularian facility (Appypark) at @MSarsCentre for many years. Now she is sharing her experience with our colleagues from @OISTedu @luslab @evodevogenomeUB and learning about the different cryptospecies of O. dioica in Okinawa
Image from Chourrout lab (@AppyGenetics)
1
2
1
13
1,772
Postdoc #SimonHenriet does not fear working in non - conventional biological models. He is the first one to sequence, analyze and uncover the mysteries of Fritillaria borealis, a larvacean with striking genomic features. @MSarsCentre @OISTedu
Image from Chourrout lab (@AppyGenetics)
2
12
285
We are so proud of our postdoc @maxiaofei320 who is uncovering the role of Hox proteins in O. dioica - Norway. CRISPR-Cas9 mutants, generated in collaboration with @CarineLG29, exhibit striking phenotypes during development. @UiB @MSarsCentre @OISTedu
Image from Chourrout lab (@AppyGenetics)
1
4
25
1,118
I am happy to announce our latest pre-print, led by MS student Seth Frazer! We can predict the color sensitivity of opsin sequences quite accurately using its gene sequence alone in machine learning models. I'll write a little thread here to explain biorxiv.org/content/10.1101/…
Discovering genotype-phenotype relationships with machine learning and the Visual Physiology Opsin...

Discovering genotype-phenotype relationships with machine learning and the Visual Physiology Opsin...

Background Predicting phenotypes from genetic variation is foundational for fields as diverse as bioengineering and global change biology, highlighting the importance of efficient methods to predict...

biorxiv.org
5
27
81
8,423
Proud to share our latest story which is out in @CurrentBiology today! The story unravels how the Ciona larvae senses its environment using polymodal sensory neurons that promotes or impede settlement and metamorphosis. I am humble to be a part of such a great team in the @mchlab
5
5
2
24
5,787
Our preprint reporting the genome of the hagfish *Eptatretus atami* has now been published in @Nature incorporating extra analyses, particularly focused on diploidisation after WGDs in vertebrates nature.com/articles/s41586-0…
Image from Ferdinand Marlétaz (@Ferdix)
5
49
2
143
10,451
Hagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences nature.com/articles/s41559-0…
1
39
101
17,468
Huge congratulations to Researcher Oleg Tolstenkov @O_Tolstenkov and Group Leader Marios Chatzigeorgiou @mchlab with Alexander Gorbushin @iephb_ras for an article published in @CommsBio on different life stages of the parasite Cryptocotyle lingua! 📸Anne Aasjord @aaasjord 👏 @UiB
Communications Biology (@CommsBio) profile pictureCommunications Biology@CommsBio19 Dec 2023
Neurobiological analysis of the fish parasite, Cryptocotyle lingua, shows streamlined signaling and the absence of key pathways, incl. nitric oxide synthase & sheds light on trematode host-infection adaptations: nature.com/articles/s42003-0… @O_Tolstenkov @mchlab @aaasjord @MSarsCentre
Image from Communications Biology (@CommsBio)
9
27
2,277
Want to understand the evolution of first brains🧠?Come join us @MSarsCentre @UiB . Postdoc position available: "Decoding the gelatinous origins of brain evolution" as part of our @HFSP grant w Fred Wolf @uniGoettingen #ctenophores. RTs highly appreciated. jobbnorge.no/en/available-jo…
5
64
6
113
25,250
Load more