Leandro Bugnon (@lbugnon) profile picture

Machine learning & bioinformatics @sinc_i.

Santa Fé, Argentina
Joined April 2010
Photo by Leandro Bugnon (@lbugnon)Photo by Leandro Bugnon (@lbugnon)Photo by Leandro Bugnon (@lbugnon)Photo by Leandro Bugnon (@lbugnon)Photo by Leandro Bugnon (@lbugnon)Photo by Leandro Bugnon (@lbugnon)Photo by Leandro Bugnon (@lbugnon)Photo by Leandro Bugnon (@lbugnon)Photo by Leandro Bugnon (@lbugnon)
Leandro Bugnon retweeted
Compré tazas para llevar a la ofi
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Leandro Bugnon retweeted
La gente que da ingeniería es la que más salida laboral tiene para hacer otra cosa en lugar de dar clases por 200.000 pesos al mes. Cuando recortan, es el primer lugar dónde se empeora la calidad educativa. – at Lanús Oeste, Argentina
"Los alumnos quieren tener salida laboral, el mercado no es mala palabra. Lamentablemente, Paulón, estudiar circo no tiene salida laboral. Necesitamos ingenieros" Gracias profe @AleCiroAlvarez por su incansable trabajo
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Leandro Bugnon retweeted
We assembled the Avengers to tackle the grammar of RBP-RNA interactions, especially how structure shapes who binds what: @MKarimzade, Lisa Fish, Heather Karner, @jjohlin, Ali Emadi, @drklly, @BoWang87, @hsnajafabadi, @LeonettiManuel
RNA-binding proteins (RBPs) recognize RNA by sequence and shape, but which matters varies by site. Introducing Pythia, an interpretable AI model trained on a new high-resolution atlas of 67 RBPs—a collaboration between the @genophoria lab, @czbiohub, @UCSF, @Calico, and @vectorinst.
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Leandro Bugnon retweeted
📣La próxima semana nos vemos en "Encuentros con la Academia"❗ “Ciencia en marcha: un encuentro con los jóvenes talentos premiados por la Academia”. 🗓️ Miércoles 14 de octubre, 18 hs. 📌 En vivo: youtube.com/@academianaciona… @hipolito1988 @RSEcheveste @marcos_tascon @marisol_osman
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Leandro Bugnon retweeted
classifiers have been around forever
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Leandro Bugnon retweeted
Jev
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GPT-6 Astraが独力でRimWorldをクリアしました!与えた指示は、「全て自分で判断し、ゲームをクリアせよ」だけ。 GPT-6はネット検索やComputer Use、外部記憶ファイルの作成・参照などを駆使し、連続襲撃に勝ち、全員を生きて惑星から脱出させました――最初のペットのチンチラも含めて。 #RimWorld
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Leandro Bugnon retweeted
💥 2026 A2B2C CONFERENCE #XVCAB2C 📣 ABSTRACT SUBMISSION IS OPEN 📌 November 9-12, 2026 👉More info: 2026.a2b2c.org.ar
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🧠 New Paper Alert! We are happy to share that our paper Exploring Sex-Related Biases in Deep Learning Models for Motor Imagery Brain Computer Interfaces has been accepted in the International Journal of Human-Computer Interaction! 🧠💻
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¡Bioinformatic Day 2026!🧬🖥️ El miércoles 22/07 nos reunimos en una jornada llena de ciencia, tecnología y futuro🚀 L@s becari@s doctorales del grupo de bioinformática tomaron la palabra para presentarnos los temas en los que vienen trabajando.
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Just look at the pattern: - Anthropic builds Claude for Science - Midjourney pivots into medical imaging - Cloud labs become infrastructure - Sequencing keeps getting cheaper - AI-native biology companies raise frontier-scale rounds - Biology is becoming a first-class problem for AI companies the software stack for biology is arriving fast as usual, the therapies will get the headlines but the infrastructure will build the next generation of iconic companies. if you're investing in this thesis, DM.
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Leandro Bugnon retweeted
Claude Science is incredible. I gave it some sequencing data, and in 8 hours it did a full analysis, generated figures, wrote a paper, submitted it for publication, got rejected, revised and resubmitted, got rejected again, it is now applying for positions in industry
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🕵🧬🖥 How to computationally discover protein functions? Just released 🔥 Our latest annotation model for domains in Pfam! 📣 ET-Pfam: an ensemble of deep models with transfer learning, now published in Bioinformatics @OxfordJournals
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Leandro Bugnon retweeted
Ayer desayunamos con la noticia de que Paul habia encontrado la "cura milagrosa" al mastocitoma de su perra Rosie con USD 3000 y usando ChatGPT/AlphaFold. Pero, ¿esto realmente es así? Les comparto mi análisis, junto a una introducción del resto los protagonistas de esta historia.
Australian tech entrepreneur Paul Conyngham explains how he used ChatGPT/AlphaFold (spent $3,000 with no biology background) to create a custom MRNA vaccine to treat his dog’s cancer tumors. Unreal.
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Leandro Bugnon retweeted
Recién depositado mi sueldo de docente universitario de Febrero. Cargo simple, 40 hs/mes. Me pagan $4570 la hora. Pero no tenemos que hacer paro porque los estudiantes 👍
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🕵🧬🖥 How to computationally annotate protein domains in Pfam? Check out our new paper! 📣 Introducing GNN2Pfam: a new model based on Graph Neural Networks, published in @JStructBiol
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Enero aun no terminó y se siente exactamente asi y esto es de lo que quiero hablar, mes a mes esto va a ir creciendo exponencialmente, por que? Porque programar herramientas requiere cada vez menos tiempo entonces mes a mes van a aparecer cada vez mas herramientas las cuales van a ser hypeadas hasta la muerte. Lo importante de esto es saber separar, dejen de darle bookmark a todo si ustedes mismos saben que no lo van a leer, no se mientan, no se sobrecarguen por querer aprender las 120 herramientas vibecodeadas que salen por dia, investiguen las que realmente les interese y no se estresen al pedo.
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We were promised programmable biology but we got indecipherable programming instead
Every biologist needs to try vibe coding, they're perfectly trained for it. Who else is totally comfortable prodding alien, indecipherable blobs with vague incantations, watching them slosh and churn with only the foggiest mental model of the intricate yet sloppy machinations churning inside the box. Then getting wildly surprising outputs that you then have to patiently corral toward something that’s, if not exactly what was in mind, at least an interesting and useful creation
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Leandro Bugnon retweeted
Hello World 👋 Today we are unveiling Boltz PBC, a Public Benefit Corporation to advance AI for biology through open science, and make it accessible to every scientist building a healthier future. Follow to stay up to date, and read more on our manifesto: boltz.bio/manifesto
Big news from Boltz today: we’re launching Boltz Lab, a new platform with new small-molecule + protein design agents, announcing Boltz PBC and a $28M seed round, and sharing a multi-year partnership with Pfizer. More below! 🚀
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