2.6 Å structure multidrug & toxic comp extrusion transporter could aid design of optim pharmacokinetic drug profiles goo.gl/mmB6Xg @nature

Light controlled membrane channel high res structures #optogenetics workhorse channelrhodopsin 2 ://goo.gl/FFsnwW goo.gl/FFsnwW

#cryoEM now with dynamics Applied to membrane receptor protein goo.gl/Z8fwgs

The only way to improve protein structures: wwPDB OneDep goo.gl/nngG2Q Paper: goo.gl/R2ZzGa

Relationship of receptor gymnastics with transmembrane signalling: biological function arising from time & length domains goo.gl/53RZdi

Status of #GPCR modeling & ligand docking goo.gl/2ogPKi

Axxam & leadXpro want to discover lead molecules for inflammation-linked #GPCR goo.gl/wkjPCN

e-book with reviews on #GPCRs and #Cancer goo.gl/JxQugH

Treasure trove: 112 pages of open access to the 'concise guide to #GPCR pharmacology 2017/18' goo.gl/rdoFXp

Apparently there's a place for #GPCR #SBDD in pest control goo.gl/EmjT8N

Liking new Data Brief publishing mechanism. Here all methodological details about homology modelling a #GPCR goo.gl/G2SWMy

Showing that a channel is open via X-ray (of mutants) & MD simulation goo.gl/E7XjSo

Fantastic structure But I wouldn't claim structure of a 'membrane protein' without showing transmembrane section goo.gl/KNiqPH

Rules for selective recruitment & retention of transmembrane proteins in rafts: surface area, length, palmitoylation goo.gl/PXNi5n

2 color #XFEL makes multi-wavelength anomalous diffraction de novo phasing possible goo.gl/dLfKa5

All (475) GPCR drugs act at 108 unique #GPCRs goo.gl/H9ZroJ

Data guide for ion channel pharmacology goo.gl/RnzuTM

Wave of non-small molecule #GPCR modulators getting into clinical trials goo.gl/H9ZroJ

Red cone #GPCR opsin dimerize, green & blue don't - because interface is different. goo.gl/zLJVz1