Postdoc at University of Cambridge
Joined December 2012
- Tweets47
- Following109
- Followers106
- Likes208
Mateusz Jaskolowski retweeted
Want to know what happens when mitochondria get stressed? Check our latest pre-print with @SimoneMattei19 lab on how mitochondria tether hibernating ribosomes as an adaptive response to glucose depletion in yeast!
biorxiv.org/content/10.1101/…
#teamtomo #cryoEM #ribosomes #mitochondria
Mateusz Jaskolowski retweeted
Pupylation is a bacterial protein modification related to ubiquitination. Want to know how the only ligase, PafA, selectively recognizes a broad range of substrates? Check out the new study by Matthias Block @MF_Block et al from @EWB_Lab.
nature.com/articles/s41467-0…
Dropping the anchor, how to TRAP a ribosome at the ER membrane!
Check out our new study describing a structure of TRAP complex interacting with the ribosome and Sec translocon published today in @NatureSMB
nature.com/articles/s41594-0…
We suggest a model where the TRAPα anchor could initiate the interactions with the ribosome, potentially even before signal sequence handover. TRAPγ stabilizes the position of TRAP at the ribosome and TRAPα-Sec61 interactions position the TRAP cradle at the Sec61 channel exit.
This study wouldn't be possible without all the amazing people from @The_Ban_Lab and @DeuerlingLab!
Big thanks to the remarkable Ahmad Jomaa @jomaa_lab and Martin Gamerdinger. Working on this project with them was a lot of fun, I enjoyed every moment!
Mateusz Jaskolowski retweeted
Happy to share our study where we show how ClpC2, a partial homolog of AAA+ chaperone ClpC1, helps #mycobacteria evade natural antibiotics targeting the essential ClpCP degradation pathway. Congrats to Gabrielle Taylor, @cui_hengjun and @JuliaLeodolter! rdcu.be/c78n6
Mateusz Jaskolowski retweeted
Check out our first preprint of the 1.55 Å cryo-EM structure of the bacterial translating ribosome!! An awesome collaboration between our group at @UVA with the @SimoneMattei19 group at the Imaging Centre at @EMBLHeidelberg and the Atkins group at @UCC biorxiv.org/content/10.1101/…
Mateusz Jaskolowski retweeted
Postdoc position is now posted, if interested please apply at: uva.wd1.myworkdayjobs.com/en…, application review starts August 23rd. Here is a sneak peak of what we do 😃👇🏼
Mateusz Jaskolowski retweeted
We are looking for a #postdoc to start in my lab @UVA on exciting #CryoEM projects studying how nascent proteins localize to #organelles in #Cancer. If you are interested please DM or send me your cv. Retweets are very welcome!!
Mateusz Jaskolowski retweeted
In recognition of his contributions to the understanding of protein synthesis, Nenad Ban of @ETH_en is being inducted into the National Academy of Sciences.
Watch the #NAS159 livestream: ow.ly/YWNK50IU6rt #biochemistry
Mateusz Jaskolowski retweeted
Thank you @TrendsBiochem and @sshaolab for the Spotlight on our recent work on NAC and SRP interplay on the ribosome!
Online now - a Spotlight from @sshaolab titled "A 'NAC' for targeting proteins to the ER".
#signalrecognitionparticle #nascentchainassociatedcomplex #nascentproteome #proteintargeting
#CSHLprotein #heat22
bit.ly/3F7qTLK
Mateusz Jaskolowski retweeted
Our department at U. Virginia has an open position in #CryoET, #TeamTomo come and join us! Please share/RT
uva.wd1.myworkdayjobs.com/en…
Mateusz Jaskolowski retweeted
Last day to apply to our postdoc position in #cryoET and #mito #genome maintenance @UCPH_CPR! Come join us in Copenhagen!
A cryo-ET postdoc in mitochondrial genome maintenance is available in my group at the University of Copenhagen. We look for someone with a deep interest in EM method development and implementation. 🧐🤖 Is that you? Application deadline is 31 January.🔬
employment.ku.dk/faculty/?sh…
Mateusz Jaskolowski retweeted
Is Alphafold-multimer overtrained ? When applying AF and AF-multi on a large set of human protein-protein interactions. We get clearly better results using the original version for about 50% of the pairs. Looking at a few examples AF-multi is just wrong (see magenta). #alphafold
Mateusz Jaskolowski retweeted
Exciting times for the EMBL Imaging Centre! We are looking forward to welcoming external users to access our latest technologies for light and electron microscopy and get support by our fantastic team members!
First open user call for the EMBL Imaging Centre!
EMBL’s new service facility for imaging is ready to offer external users high quality access and support. Researchers are encouraged to contact the EMBL IC team to discuss opportunities.
embl.org/news/lab-matters/em…
ALT A group of people standing outside a two-storey reseach building, featuring a glass front.
Mateusz Jaskolowski retweeted
Our paper on ‚sigma adaption‘ in mycobacterial transcription is out! Thank you to Andreas Müller and @EWB_Lab for this fantastic collaboration with @The_Ban_Lab
Want to know about 'sigma adaptation' and what it has to do with #transcription regulation and #DNADamageResponse in #mycobacteria?
Great collaboration by Andreas Müller @EWB_Lab and @evakummer @The_Ban_Lab!
science.org/doi/10.1126/scia… science.org/doi/10.1126/scia…
Mateusz Jaskolowski retweeted
Check out *NabFab*, the robust and convenient solution to combine your nanobodies with the fiducial properties of a Fab. Out now in
@PNASNews. Many thanks to all coauthors!! #cryoEM #MembraneProteins
pnas.org/content/118/47/e211…
Mateusz Jaskolowski retweeted
There is a lot of pressure on academics to be extraordinarily successful. Is it worth it?
theatlantic.com/family/archi…
