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Côté Lab (@mpcotelab) profile picture

Côté Lab

@mpcotelab

Drexel College of Med. | Neurobiology & Anatomy. Our research focuses on plasticity and functional recovery after spinal cord injury. Account is managed by lab

 East Falls, Philadelphia
cote-lab.org
Joined July 2018
  • Tweets40
  • Following63
  • Followers105
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Photo by Côté Lab (@mpcotelab)Photo by Côté Lab (@mpcotelab)Photo by Côté Lab (@mpcotelab)Photo by Côté Lab (@mpcotelab)Photo by Côté Lab (@mpcotelab)
Multi-session transcutaneous spinal cord stimulation prevents chloride homeostasis imbalance and the development of spasticity after ... biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Preprint of our @mpcotelab latest work using noninvasive spinal cord stimulation to mitigate the development of spasticity after spinal cord injury! biorxiv.org/content/10.1101/…
Multi-session transcutaneous spinal cord stimulation prevents chloride homeostasis imbalance and...

Multi-session transcutaneous spinal cord stimulation prevents chloride homeostasis imbalance and...

Spasticity is a complex and multidimensional disorder that impacts nearly 75% of individuals with spinal cord injury (SCI) and currently lacks adequate treatment options. This sensorimotor condition...

biorxiv.org
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KCC2 Enhancers Normalize Reflex Responses and Improve Locomotor Function after Chronic Spinal Cord Injury biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Côté Lab retweeted
J Bilchak (@bilchak_j) profile picture
J Bilchak@bilchak_j23 Oct 2023
Absolutely thrilled to share our latest preprint from the @mpcotelab demonstrating the effects of KCC2 enhancers on reflex and locomotor pathways after SCI! @simonmdanner @gwihelm
bioRxiv Neuroscience (@biorxiv_neursci) profile picturebioRxiv Neuroscience@biorxiv_neursci23 Oct 2023
KCC2 Enhancers Normalize Reflex Responses and Improve Locomotor Function after Chronic Spinal Cord Injury biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Replying to @gwihelm
@gwihelm, @bilchak_j and @mpcotelab (@mmscrc) show how bumetanide changes postsynaptic inhibition after chronic SCI and step-training! 📜buff.ly/3mBhxCS
Image from Journal of Physiology (@JPhysiol)
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Côté Lab retweeted
J Bilchak (@bilchak_j) profile picture
J Bilchak@bilchak_j1 Mar 2023
physoc.onlinelibrary.wiley.c… New paper hot off the press! @gwihelm @mpcotelab
Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition...

Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition...

Abstract figure legend After chronic spinal cord injury (SCI), presynaptic inhibition and postsynaptic inhibition of the monosynaptic reflex are decreased in decerebrated rats. Here we show that a...

physoc.onlinelibrary.wiley.com
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Interested in an NIH-funded post-doc in an outstanding research laboratory at the University of Florida? If so, check out the details on the laboratory website of Dr. Ashley Smuder in the Department of Applied Physiology and Kinesiology sites.google.com/view/mcmlab
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Proud to show you my work at @mpcotelab. In this study, I developed a decerebrated rat preparation to investigate the effects of spinal cord injury and step-training on the presynaptic inhibition that was first described by John Eccles et coll. in the 60s. physoc.onlinelibrary.wiley.c…
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Côté Lab retweeted
J Bilchak (@bilchak_j) profile picture
J Bilchak@bilchak_j6 May 2020
And another one hot off our bench! @gwihelm uses a decerebrated prep to show how pre-synpatic inhibition is reorganized after chronic SCI and restored with step-training biorxiv.org/content/10.1101/…
Direct evidence for decreased presynaptic inhibition evoked by PBSt group I muscle afferents after...

Direct evidence for decreased presynaptic inhibition evoked by PBSt group I muscle afferents after...

Spinal cord injury (SCI) results in the disruption of supraspinal control of spinal networks and an increase in the relative influence of afferent feedback to sublesional neural networks, both of...

biorxiv.org
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Côté Lab retweeted
J Bilchak (@bilchak_j) profile picture
J Bilchak@bilchak_j30 Apr 2020
Congrats Simon! @simonmdanner
IOP Publishing (@IOPPublishing) profile pictureIOP Publishing@IOPPublishing30 Apr 2020
Dr Simon Danner, the JNE #Reviewer of the Year, says: "Several of my papers received constructive reviews that significantly improved their quality. I strive to provide same thorough comments to others that I have benefited from." #PeerReview ow.ly/DMMP50zsYLO
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Côté Lab retweeted
J Bilchak (@bilchak_j) profile picture
J Bilchak@bilchak_j26 Apr 2020
If you're curious about how chloride extrusion enhancers affect spastic symptoms after spinal cord injury, check out my first paper, hot off the bench! And if you're not, check it out anyway ;) biorxiv.org/content/10.1101/…

Enhancing KCC2 activity decreases hyperreflexia and spasticity after chronic SCI

After spinal cord injury (SCI), the majority of individuals develop spasticity, a debilitating condition involving involuntary movements, co-contraction of antagonistic muscles, and hyperreflexia. By...

biorxiv.org
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Congratulations to Margo Randelman for winning the Goldstein Award at the National Neurotrauma meeting in Pittsburgh! @DrexelMedicine @DrexelNews @DrexelUniv @LZholudeva @Neurotrauma #NNS2019 #spinalcordinjury #MMSCRC – at Pittsburgh, PA
Image from Michael Lane (@mlane_neuro)
Image from Michael Lane (@mlane_neuro)
Image from Michael Lane (@mlane_neuro)
Image from Michael Lane (@mlane_neuro)
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Nimodipine prevents the development of spasticity after spinal cord injury biorxiv.org/cgi/content/shor… #bioRxiv
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Proud to announce that my first PhD student, Eugene Mironets successfully defended his thesis this week! His work looks at how spinal inflammation contributes to sympathetic dysregulation after SCI. Congratulations 🎈🎉🍾
Image from Veronica Tom (@VeronicaTomlab)
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Spectacular start to the annual ASIA meeting in Honolulu! Looking forward to a productive week of spinal cord injury research. #SpinalCordInjury @DrexelMedicine @DrexelNews @ASIA_spine @mpcotelab @LZholudeva – at Honolulu, HI
Image from Michael Lane (@mlane_neuro)
Image from Michael Lane (@mlane_neuro)
Image from Michael Lane (@mlane_neuro)
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Recently published collaboration with the Baas lab. Excellent work @4ndrewmatamoro5!
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The Tom lab represented well at discovery day! Congrats to Micaela O’Reilly, @EugeneMironets, and all the awardees!!!!
Image from Veronica Tom (@VeronicaTomlab)
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Hot off the press! 🗞️🗞️🗞️ Neural Interactions between Transspinal Evoked Potentials and Muscle Spindle Afferents in Humans by Drs. Murray and @mariaknikou! Click the link! #klab4recovery #spinalcordinjury #rehabilitationresearch #publication sciencedirect.com/science/ar…
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Côté Lab retweeted
J Bilchak (@bilchak_j) profile picture
J Bilchak@bilchak_j27 Sep 2018
Was super happy to be able to present my data at the NSAS course on spinal cord injury to such amazing researchers. :) (Spot the difference):
Image from J Bilchak (@bilchak_j)
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Robot-assisted therapy enables effective and intensive training, ensuring the optimal exploitation of neuroplasticity and recovery potential. #klab4recovery #rehabilitationresearch #lokomat
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