Michael Terns (@mpterns) profile picture

Michael Terns

@mpterns

Regent’s Research Professor at The University of Georgia investigating CRISPR biology and applications

 Athens, GA
ternslab.uga.edu
Joined January 2016
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  • Following570
  • Followers616
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Photo by Michael Terns (@mpterns)Photo by Michael Terns (@mpterns)Photo by Michael Terns (@mpterns)
My lab has postdoc openings in the following areas: 1) Structural biology and single molecule biophysics; 2) Developing novel genome editing methods; and 3) Protein and RNA engineering. Please share the info with your trainees, and RT please. 🙏 postdocs.yale.edu/yale-postd…
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It was such a treat to host Michael Terns (@mpterns) for a seminar here at @Penn yesterday! We got to hear the latest about archaeal adaptive immunity (CRISPR)! And chat over some🍸😃
Image from Andrew Santiago-Frangos, PhD (@SantiagoFrangos)
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OUT NOW CRISPR systems canonically protect against invading viral DNA, but could they also influence parasitic associations between archaea? nature.com/articles/s41564-0…
CRISPR-influenced symbiosis

CRISPR-influenced symbiosis

Nature Microbiology - CRISPR systems canonically confer microorganisms with protection against invading viral DNA, plasmids and mobile genetic elements, however a multi-omics investigation of deep...

nature.com
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OUT NOW 👉Histones direct site-specific CRISPR spacer acquisition in model archaeon nature.com/articles/s41564-0…
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A self-transmissible plasmid from a hyperthermophile that facilitates genetic modification of diverse Archaea pubmed.ncbi.nlm.nih.gov/3727… A great work from Ryan Catchpole who designs a universal genetic tool for #hyperthermophiles #archaea
A self-transmissible plasmid from a hyperthermophile that facilitates genetic modification of...

A self-transmissible plasmid from a hyperthermophile that facilitates genetic modification of...

Conjugative plasmids are self-transmissible mobile genetic elements that transfer DNA between host cells via type IV secretion systems (T4SS). While T4SS-mediated conjugation has been well-studied in...

pubmed.ncbi.nlm.nih.gov
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I am excited to share with you the final version of my work @SorekLab studying 💠How bacterial immune systems sense phage infection💠 Published now in @CellCellPress🍻 cell.com/cell/fulltext/S0092… See thread below for a recap and highlights added during the review process ⬇️ 1/11
Discovery of phage determinants that confer sensitivity to bacterial immune systems

Discovery of phage determinants that confer sensitivity to bacterial immune systems

A tour de force analysis provides fresh insights into the ways in which bacterial immune systems sense phage invaders and how the latter escape the defense mechanism.

cell.com
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Michael Terns retweeted
Feng Zhang (@zhangf) profile picture
Feng Zhang
@zhangf29 Mar 2023
Delivery of therapeutic molecules is a major bottleneck for treating a wide range of diseases. Today we describe a new modality for delivering proteins based on an engineered contractile injection system @nature nature.com/articles/s41586-0…
Image from Feng Zhang (@zhangf)
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Michael Terns retweeted
Aravind group (@jivarahasya) profile picture
Aravind group@jivarahasya21 Mar 2023
A postdoc position is open in our lab at NLM/NIH intramural research program for candidates with a strong knowledge of computational approaches to study protein evolution & structure + genomics + biochemistry/biology. Please RT & if interested, apply via training.nih.gov/postdoc_job…
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One more week to apply! We have so many cool things going on (AAV, gene editing, single cell transcriptomics, transcriptional recording, disease models) and we need your help!
Randall Platt (@randall_platt) profile pictureRandall Platt@randall_platt6 Mar 2023
🚨Job alert🚨 We are recruiting a postdoc for a project focused on development of AAV vectors for gene and cell therapy. Come join us in Basel, Switzerland! More info at: jobs.ethz.ch/job/view/JOPG_e…
Image from Randall Platt (@randall_platt)
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Michael Terns retweeted
Peter Fineran (@PeterFineran) profile picture
Peter Fineran@PeterFineran8 Feb 2023
Hi #CRISPR enthusiasts. #CRISPR2024 is being hosted in #NewZealand by @dsashital, @gavinjknott, @drbridgetwatson and I. If you are thinking of attending, help us lock in a date by completing the following survey surveymonkey.co.uk/r/WYZM58Q. Pls RT @crispr2023
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Cool study. Congratulations to the teams!
Joe Bondy-Denomy (@joeBondyDenomy) profile pictureJoe Bondy-Denomy@joeBondyDenomy6 Feb 2023
#Phages have to deal with so much just to get by. CBASS (related to cGAS-STING) is a really common defense system, just like #CRISPR. Here, Erin and Xueli figure out a couple of ways that phages get around CBASS. Many more #CBASS questions remain! Check out the thread from Erin.
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Michael Terns retweeted
Daan C. Swarts (@DCSwarts) profile picture
Daan C. Swarts@DCSwarts20 Oct 2022
Great opportunity for (future) group leaders in synthetic biology at @WUR !
María Suárez Diez (@MariaSuarezDiez) profile pictureMaría Suárez Diez@MariaSuarezDiez19 Oct 2022
Great opportunity at @wur at @SSB_WUR. We are #hiring a new group leader in synthetic biology. wur.nl/en/vacancy/assistant-…
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Michael Terns retweeted
Daan C. Swarts (@DCSwarts) profile picture
Daan C. Swarts@DCSwarts20 Oct 2022
We have a vacancy for a technician with experience in protein expression/FPLC-based purification in our team at Biochemistry @WUR! Interested in performing/supporting our research (swartslab.org)? Info & application: wur.nl/en/vacancy/research-t… Sharing (RT) is caring!
Research in the Swarts lab focusses on the functional, structural, and mechanistic characterization...

Research in the Swarts lab focusses on the functional, structural, and mechanistic characterization...

Wageningen University, Laboratory of Biochemistry

swartslab.org
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What is there to know about archaeal cell biology, out today in @NatureMicrobiol fun collaboration with @marleenvw @SGribaldo Andre Pulschen and @BaumBuzz rdcu.be/cXJPv
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Do you want to work on molecular tools for rejuvenation? We're hiring and looking for a postdoc to join us to work on novel approaches for reprogramming aged cells. Recently got an R01 for this cool project and many directions ongoing. Please RT & apply! careers.peopleclick.com/care…
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Michael Terns retweeted
CRISPR2026 (@crisprmeeting) profile picture
CRISPR2026@crisprmeeting11 Oct 2022
We are happy to announce that the CRISPR2023 website is live! Go to crispr2023.info/ for updates and more!
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Spread the word! The Ke lab has two new postdoc openings. We aim to convert first-hand mechanistic understanding of RNA-guided systems into novel genome editing applications. RT please. academicjobsonline.org/ajo/j… academicjobsonline.org/ajo/j…
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Don't miss this one: the whole new #graduate program „RNAmed—Future Leaders in #RNA-based #Medicine“ through the Elite Network Bavaria, Germany, is offering 15 fully-funded #PhD positions (4 years) in Würzburg, Munich or Regensburg. 👉Apply by Sept 15 via rnamed.de.
Image from Helmholtz Institute Würzburg (HIRI) (@Helmholtz_HIRI)
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CRISPR can cut DNA and RNA, but did you ever wonder other activities might exist? Today in @biorxivpreprint, we show that the Type III-E Cas7-11 system programmably activates a nearby protease as part of microbial defense. + @jgooten @hnisimasu 🧵👇🏼biorxiv.org/content/10.1101/… 1/9
RNA-triggered protein cleavage and cell death by the RNA-guided type III-E CRISPR-Cas nuclease-pr...

RNA-triggered protein cleavage and cell death by the RNA-guided type III-E CRISPR-Cas nuclease-pr...

The type III-E Cas7-11 effector nuclease forms a complex with a CRISPR RNA (crRNA) and the putative caspase-like protease Csx29, catalyzes crRNA-guided target RNA cleavage, and has been used for RNA...

biorxiv.org
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Postdocs, a construction coordinator, a scientific coordinator... 🧑‍🔬👷🧑‍💻 We have several job offers at the moment. Come and join the #HIRI family! helmholtz-hiri.de/en/jobs-ta…
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