Scientific Director and President at Laureate Institute for Brain Research and Professor of Psychiatry at UCSD

Tulsa, OK
Joined January 2017
Beautiful work by Haixia Zheng ( laureateinstitute.org/haixia… ) showing that CMV-associated T-cell differentiation may be a candidate pathway to depression risk: doi.org/10.1016/j.bbi.2026.1…
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This was a great team effort with @royperlis @CRodriguezMDPhD @JohnTorousMD @KhalsaLab @pshrink and [email protected] based on the workgroup meeting at #ACNP in January of 2026, there are some useful directions and suggestions here: rdcu.be/fA4UR
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In a new viewpoint piece, jamanetwork.com/journals/jam… deployment of LLMs in psychiatry requires strict oversight to @JohnTorousMD and I argue that mental health practitioners need specific training to prevent fluent but fabricated clinical narratives.
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To mitigate automation bias, implement a SEIG loop: 1️⃣ Specify task bounds 2️⃣ Elicit structured data 3️⃣ Interrogate assumptions 4️⃣ Ground claims in the record LLMs function as bounded hypothesis generators, not autonomous actors. #ComputationalPsychiatry #ClinicalAI #HealthTech
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How do anxiety disorders, OCD, and PTSD change our behavior? Our neuroimaging research, out now in Molecular Psychiatry, shows: it's about more than the diagnosis. ⬇️ Learn more: doi.org/10.1038/s41380-026-0…
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Martin Paulus retweeted
I'm excited to share our new paper published today in JAMA Psychiatry: jamanetwork.com/journals/jam…
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Martin Paulus retweeted
Replying to @EricTopol
MIT has a AI program that does this as Open AI.
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AI is becoming clinically relevant for mood and anxiety care—but the evidence is uneven, and enthusiasm must be matched by guardrails. I point out that the priority now is not “AI everywhere,” but actionable, validated, clinically accountable tools that improve care.
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Martin Paulus retweeted
We have less than 1 week until the Embodied Minds Summit, and the agenda is finalized! embodiedminds.ai/ If you are still waiting for an invitation, the final wave for this small invite-only meeting will be going out later today, so stay tuned.
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Martin Paulus retweeted
The draft agenda for the UCLA Embodied Minds Summit is now live on the website! See “Day 2 — The Conference”. It contains the workshop assignments and speaker order. embodiedminds.ai/
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At the Annual UNL Symposium on Motivation
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Great new review by Adrienne Taren: tandfonline.com/doi/full/10.…
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Hilarious 😂
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This is what I see
GPT-5 Pro just scored a 148 IQ on the official Mensa Norway test that’s genius territory. This isn’t a cherry-picked result either… it’s the average over multiple runs. We’re now looking at an AI that outperforms almost every human on Earth in raw problem-solving ability. The “AI will never match human intelligence” crowd just got left in the dust.
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Coming in September 2025 are 16 chapters by experts on "The Bodily Self, Emotion, and Subjective Time: Exploring Interoception through the Contributions of A.D. (Bud) Craig". Stay tuned for my presentation of online chapters already available online. link.springer.com/book/97830…?
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🎧🧠Inspired by @LIBR_Tulsa-@mpwpaulus's great idea, I used @Google's NotebookLM to turn one of my thesis papers into a podcast—and it worked really well! ▶️Give it a listen: drive.google.com/file/d/1SDh… 📄 You can check out the original paper here: nature.com/articles/s41598-0…
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A labor of love with my friend and long-time collaborator Murray B. Stein. Addressing Difficult-to-Treat Anxiety: A review integrating computational psychiatry, systems neuroscience, & novel interventions. Mechanistic insights for precision psychiatry. biologicalpsychiatrycnni.org…
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Great work by Wes Thompson, Evan White and Chun Chieh Fan at LIBR as well as others: The promise of population neuroscience: understanding brains across diverse groups.
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