he/him. Geneticist & 1x programmer. Bioinformatics Scientist. I'm not here. @williamrowell.dev on bsky; @williamrowell@genomic.social; @billy@social.lol
East Bay, CA
Joined March 2007
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Billy 馃尮 retweeted
Ready to advance your plant or animal research with free HiFi sequencing? 馃尡馃惥
The 2026 #PacBio Fiber-seq SMRT Grant is open!
In 100 words or less, tell us how HiFi sequencing with @epicypher Fiber-seq could advance your research.
Apply now: bit.ly/4zR5qBF
Billy 馃尮 retweeted
How can one HiFi dataset reveal multiple types of genomic variation?
The #PacBio WGS Variant Pipeline brings together tools for structural variants, repeats, phasing & methylation.
Explore the workflow and our new guide in the blog.
Read more: bit.ly/4ySMEct
Billy 馃尮 retweeted
New on hg38: Fiber-seq, from the Stergachis and Vollger labs. One PacBio read reports sequence, chromatin accessibility and CpG methylation together, and is long enough to phase.
See our news for more: bit.ly/ucscGBfiberseq
ALT The imprinting control region of the KCNQ1OT1 long non-coding RNA on chromosome 11, in K562. Across the highlighted region the CpGs on one haplotype are nearly all methylated and those on the other are nearly all unmethylated, and it is the unmethylated haplotype that is open. The bottom track plots the difference between the two, red where it is most significant. Loss of methylation here has been associated with Beckwith-Wiedemann syndrome.
Billy 馃尮 retweeted
#PacBio is heading to Seattle for #AMP2026! 馃К
Explore how HiFi sequencing helps researchers resolve complex variants, capture entire genes & reveal phasing and methylation in a single workflow.
See what's planned and explore our full program: bit.ly/4yOsOyU
Billy 馃尮 retweeted
The failures of governance in California are broadly the failures of weak progressive governance, not strong progressive governance. PG&E should've been socialized and turned into a public utility any of a half-dozen times in its history.
Billy 馃尮 retweeted
interview-driven development is seeking conflicts and moments of growth so you can one day have a good answer for "tell us about a time someone gave you feedback and how you responded"
Billy 馃尮 retweeted
COWORKER: we need to find the root cause asap
ME: *takes long drag* the root cause is that our processes are not robust enough to prevent a person from making this mistake
COWORKER: amy please not right now
