Nicolas S. Piuzzi, MD

What an amazing night last week watching the Guardians with our Cleveland Clinic Adult Reconstruction–CCARR research team and their families! ⚾️ I could not feel more fortunate to work alongside such an extraordinary group of people (Research coordinators, Research assistant, medical students, research fellowS, etc). What we accomplish and do matters, but the people, trust, and shared purpose behind it are what make the journey truly meaningful. “The best interest of the patient is the only interest to be considered, and in order that the sick may have the benefit of advancing knowledge, union of forces is necessary.” — William J. Mayo, MD Grateful for this team, our families, and the opportunity to keep building, learning, and advancing care together. Go TEAM! ⚾️❤️ #TripartiteMission

🚨 Hydration breaks have to go @FIFAcom @FIFAWorldCup Let’s stop pretending these are about football. Players already hydrate during injuries, substitutions, VAR reviews, and goal celebrations. If player safety is the priority, let them drink during those natural stoppages. Instead, every match gets an extra 90-second TV timeout that kills momentum, cools the atmosphere, and disrupts the rhythm of the game. 📺💰 Football isn’t basketball or American football. Its beauty is the continuous flow. ⚽❤️ Bring back uninterrupted football. Who else is ready to end the commercial timeout disguised as a hydration break? 👇 #Football #Soccer #WorldCup #FIFA #LetThemPlay #KeepTheGameFlowing #FansFirst #TheBeautifulGame #NoMoreHydrationBreaks #GameFlow

No respect for the status quo. Respect people, respect data, respect patients …but never unquestioned dogma. Progress happens when we challenge assumptions and refuse to accept “this is how we’ve always done it.” 🏥 @NEJM @jbjs nejm.org/doi/full/10.1056/NE…

Honored to meet @Schwarzenegger today at the American Academy of Orthopaedic Surgeons #AAOS2026 Annual Meeting @AAOSAdvocacy As Chief Movement Officer at Zimmer Biomet, he is elevating a critical issue: Musculoskeletal disease = #1 cause of disability worldwide ➡️ affecting ~1.7 billion people Promoting movement & mobility is essential to extend HEALTHSPAN and improve quality of life. 🦵🚶‍♂️ Arnold’s journey reflects values that resonate deeply in medicine and surgery: discipline, ambition, and the courage to pursue big goals. Two reminders that still resonate: “Don’t be afraid to fail.” “Stay hungry.” In orthopaedics we see it every day: Restore movement → restore quality of life. Grateful to see such a powerful advocate for movement & musculoskeletal health. 💪 🦾 #AAOS #Orthopaedics #Healthspan #MovementIsMedicine #THANKYOU

Congrats to CCARR TEAM on their #AAOS2026 podium 👏 “One Size Fits None”: 1-yr THA clinically meaningful improvement thresholds vary 2–3x by baseline PROM phenotype. Universal MCID/PASS/SCB cut-points fail heterogeneous patients. Personalized benchmarking is the future. #PROMs #THA #AAOS @jbjs @AAOS1

Presented at #AAOS2026 CMS PRO-PM began in 2024 • PROMs required for ≥50% THA/TKA • Payment impact starts 2028 82% of primary THA pts have contralateral hip or back pain — significantly affecting 1-yr SCB & satisfaction. Risk stratification matters. #AAOS #PROMs #THA #ValueBasedCare

Huge congratulations to @shujaaK & our @ClevelandClinic Adult Reconstruction Research (CCARR) team at #AAOS 👏 “Cefazolin for All: Safe Implementation of Updated Antibiotic Guidelines in 12,849 Arthroplasty Patients.” in 12,849 arthroplasty pts: ✅ ↑ First-line antibiotic use ✅ ↓ Hypersensitivity events ✅ No increase in readmissions or mortality Data-driven orthopaedics in action.

📊 Today I paused for a moment: 500 publications on PubMed I never imagined getting here, and it was never the goal This isn’t about volume. It’s about compounded impact 📈 The 1% principle explains it best: Doing 101% instead of 99%, every single day, asking questions, tightening one analysis, mentoring one trainee, refining one paragraph, compounds into outcomes that are orders of magnitude apart over time This philosophy has guided my career: perseverance, consistency, rigor, and collaboration, always focused on evidence that genuinely improves patient care: from infection and revision arthroplasty to PROMs, value-based care, and innovation at scale And this is not an individual achievement 99% belongs to the TEAM: trainees, research staff, collaborators, mentors, and above all, the patients who trusted us with their data and their stories 🙏 Deeply grateful. Still motivated. Impact is built daily. 101% > 99% pubmed.ncbi.nlm.nih.gov/?ter… @jbjs @ClevelandClinic

If you want to go fast, go alone; If you want to go far, go with a team!

Save Piriformis!

Cannot ask for better follow-up appointment! 🦾 4 month FUP THA

Could not have asked for better partners. The origin of the word PARTNER: from the Latin partire, “to share” which captures exactly what this group represents: people who share purpose, values, hard work, and the drive to build something meaningful together. These are not just partners, but true friends. Grateful to share the journey with each of you. CCARR - Cleveland Clinic Adult Reconstruction Research 🦾

Cleveland Clinic Adult Reconstruction Research - Holiday Party 🎄🦴✨ Amazing CCARR Holiday Party! Grateful for this team, your stories, your growth, and the impact you make every day. Honored to walk this journey with you. 🤍🙌 #CCARR #TeamS #ClevelandClinic #Orthopaedics 🎉

Beautiful. @jbjs New era - jbjs.org/issue.php

#AAHKS2025 @AAHKS @CleClinicArthGp Ready to roll 🎸

Thank you UCSF! Grateful to the residents, fellows, and staff from the Department of Orthopaedic Surgery - especially the Joint Reconstruction section - for such a warm welcome. It was an amazing experience to connect, share ideas, cases and learn from such an outstanding team. You have built something truly special, a remarkable program and a genuine family. 👏💙 Erik Hansen🥇 @UCSF

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