CONGRESS | #EULAR2026 | PRESENTATION Ioannis Parodis shares interim data from the ReBioLup study, evaluating 1-year clinical and histopathological outcomes in incident #LupusNephritis (N = 168). • At 1 year, UPCR at repeat biopsy moderately correlated with NIH AI at repeat biopsy (Spearman’s ρ = 0.48; p = 0.001), although 17% of patients had minimal proteinuria (UPCR <0.5 g/g) with persistently high intrarenal activity (NIH AI ≥4). • Among patients with NIH AI ≥4 at 12 months, 66.7% were complete renal responders. • Overall, 10.6% of patients had UPCR >1 g/g but NIH AI <3. Findings highlight discordance between proteinuria and kidney histopathology, supporting repeat biopsy to guide treatment adaptation. Follow our live feed for more updates: bit.ly/4wS95Pf Intended for HCPs only. This congress coverage is independently supported by pharmaceutical companies, who are allowed no influence on the content; a full list of supporters can be found on our website. #RheumTwitter #rheumatology #MedNews #MedEd #MedicalCongress #lupus @IoannisParodis @KarolinskaInst