Exploring and expanding non-conventional druggable space. Postdoc in the @disney_lab (Scripps Research), @StephanHacker2 lab alumnus (TU Munich, Uni Leiden)
Jupiter, FL, USA
Joined January 2020
- Tweets39
- Following247
- Followers163
- Likes1.4K
Patrick Zanon retweeted
Congratulations Jess sam and team on study to manipulate rna quality control in neurons/mice to eliminate disease RNAs - RNA-targeted small molecule triggers elimination of r(G4C2)exp in c9ALS/FTD via the nuclear RNA exosome | PNAS pnas.org/doi/10.1073/pnas.22…
Patrick Zanon retweeted
Congrats to Sam and Team - DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC) pubs.acs.org/doi/10.1021/jac…
Patrick Zanon retweeted
Just found out that our isotopically labeled desthiobiotin azide (isoDTB) tags (doi.org/10.1002/anie.2019120…) for residue-specific chemoproteomics using a variant of isoTOP-ABPP are now commercially available. clickchemistrytools.com/prod…
Patrick Zanon retweeted
Congratulations to Hamish on new paper - Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA pubs.acs.org/doi/10.1021/jac…
Patrick Zanon retweeted
@AntheJanssen and I have a fully-funded, 4-year PhD position for a researcher interested in computational and chemical biology approaches to develop new antibiotics. Join us to do great science in beautiful Leiden @UniLeiden @LeidenScienceEN @LeidenScience universiteitleiden.nl/en/vac…
Patrick Zanon retweeted
Join us for the 2nd Munich-Leiden Virtual @ChemBioTalks! A very exciting lineup of speakers and the first time that we will also include flash talks by PhD students and postdocs. If you want to actively participate in that way, make sure to look at the abstract challenge.
We are excited to share the full program of the 2nd Munich-Leiden Virtual ChemBio Talks on September 27th, 2022 with talks by @ChemicalBiology, Herbert Waldmann, Zhengqiu Li, @kimbonger, @Adam_S_Nelson, @RentmeisterLab and @hargrovelab. Free registration: events.bizzabo.com/402968/ho…
Patrick Zanon retweeted
Today in @eLife we reveal the mechanism of action of a large family of highly cytotoxic lipids and show how it can be exploited. Opens many applications, since novel molecules with selective cytotoxic effects can be designed from this elifesciences.org/articles/7…
Patrick Zanon retweeted
Excited that this great study led by @SebBritton1 is out @eLife. Very happy that @patrick_zanon and I could make a contribution using residue-specific proteomics. Check it out to learn how SDRs oxidize alkynylcarbinols into protein-reactive electrophiles. doi.org/10.7554/eLife.73913
Patrick Zanon retweeted
Very excited that our former group member @patrick_zanon received one of the GDCh Division of Medicinal Chemistry's 2022 PhD Awards for his PhD thesis at the Frontiers in Medicinal Chemistry #fimc2022 @GDCh_aktuell. Congratulations, Patrick! #proudPI
Patrick Zanon retweeted
I am glad to share our new optimised chemical proteomic workflow for low protein input in 96-well plate, we call it SP2E. Easy, robust and fast. Try it out! We used it for analysis of AMPylation and O-GlcNAcylation. Thanks to Tobias and all coauthors. biorxiv.org/content/10.1101/…
Patrick Zanon retweeted
Our group has a few postdoc positions open on rna chemical biology esp degraders. If you have base skills in organic synthesis, structural biology/biophysics/biochemistry, or informatics and are interested pls email me at [email protected]
Patrick Zanon retweeted
I am still looking for talented PhD candidates!
We have funding and exciting projects in the field of early drug discovery! pomplunlab.com/open-position…
Looking for background in (and love for) organic synthesis!
@LeidenScienceEN #chemjobs #medchem #chembio
Patrick Zanon retweeted
Congratulations to @ListLaboratory and @MacMillan_Lab on the @NobelPrize for their amazing work on asymmetric organocatalysis!
Here's a throwback to about two years ago, when @ben_list gave a talk at our CheMUC Campus Event together with @DaumannL, @DavidBKonrad and Golo Storch!
Patrick Zanon retweeted
Interested in integrating #FragPipe in your Chemical Proteomics workflow? Listed to this webinar by our terrific collaborators, presented by Patrick Zanon from @StephanHacker2 lab. One area where we are putting a lot of effort, new collaborations welcomed! youtube.com/watch?v=qEDDCLsc…
Patrick Zanon retweeted
In case you missed the talk by @patrick_zanon at the @LPDGproteomics seminar, check out the recording on @YouTube #proudPI: youtube.com/watch?v=qEDDCLsc…. Learn about our chemoproteomic experiments to study electrophile reactivity using a #FragPipe workflow developed by @nesvilab.
@patrick_zanon gave an excellent talk at the @LPDGproteomics seminar presenting our recent @ChemRxiv preprint on the proteome-wide reactivity of diverse electrophiles. #proudPI (1/3) doi.org/10.26434/chemrxiv.14…
Patrick Zanon retweeted
We are excited to announce the 1st Munich-Leiden Virtual ChemBio Talks taking place on September 14th from 2:50 p.m. to 8:30 p.m. CEST with many exciting talks including the keynotes by @CarolynBertozzi and Ben Cravatt. Registration is free, but required. qrco.de/bcAvRP
Patrick Zanon retweeted
I reached 2⃣2⃣2⃣2⃣ followers! To celebrate, some personal news: We will be moving to the Leiden Institute of Chemistry @LeidenScienceEN, where I will become an Assistant Professor in the Department of Molecular Physiology. Very much looking forward to this great opportunity!(1/9)
Patrick Zanon retweeted
Very excited that @patrick_zanon will have the opportunity to present our recent preprint at the LPDG webinar on June 18th. If you want to learn more on how we study the amino acid selectivity of diverse electrophiles proteome-wide, make sure to attend(1/2)doi.org/10.26434/chemrxiv.14…
Hello All,
Please see our next LPDG webinar on Fri 18th June, focused on chemical proteomics! We have an exciting line up speakers, including Ilaria Piazza
@theWittySquare and Patrick Zanon @patrick_zanon, with guest chair Marcus Bantscheff @MBantscheff.
Patrick Zanon retweeted
Thank you, @Dereklowe, for highlighting our @ChemRxiv preprint in the blog "In the Pipeline". We are very glad that you liked our work and we hope that you are right, that this will become a valuable resource for the covalent inhibitor community. doi.org/10.26434/chemrxiv.14…
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Patrick Zanon retweeted
I also want to give a thread on the findings in our @ChemRxiv preprint that profiles the proteome-wide amino acid selectivity of diverse electrophilic alkyne probes. (1/10) doi.org/10.26434/chemrxiv.14…
Very excited that our proteome-wide profiling of the amino acid selectivity of 54 diverse electrophilic alkyne probes is out on @ChemRxiv. A great collaboration with @nesvilab, @Toste_Group, @klanglab and @christhechang led by first author @patrick_zanon. doi.org/10.26434/chemrxiv.14…