Adam Fleischhacker PhD, MBA (@preposterior) header
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Accelerating towards better outcomes.

Maryland, USA
Joined April 2016
Photo by Adam Fleischhacker PhD, MBA (@preposterior)Photo by Adam Fleischhacker PhD, MBA (@preposterior)Photo by Adam Fleischhacker PhD, MBA (@preposterior)Photo by Adam Fleischhacker PhD, MBA (@preposterior)Photo by Adam Fleischhacker PhD, MBA (@preposterior)Photo by Adam Fleischhacker PhD, MBA (@preposterior)Photo by Adam Fleischhacker PhD, MBA (@preposterior)Photo by Adam Fleischhacker PhD, MBA (@preposterior)Photo by Adam Fleischhacker PhD, MBA (@preposterior)Photo by Adam Fleischhacker PhD, MBA (@preposterior)
Made an introductory 📕(draft) about using Python for Bayesian Inference and unifying narrative, math, and code. People seem to find it helpful. Check it out. Feedback encouraged. persuasivepython.com/ #DataScience #Python #bayes #Stats #probabilisticprogramming
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Adam Fleischhacker PhD, MBA retweeted
My colleagues at Dartmouth developed a very cool tool for AI-proof homework assignments. It's called deb8.tv — students get paired and have live video debates with one another. You can get a transcript, use an AI as judge if you want. 1/
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A very useful report on how AI is affecting student learning at MIT. I like this term cognitive surrender, "where students fall back on AI at the first hint of struggle." We need to encourage undergrads (and all humans) to recognize this pattern and resist it.
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The thing about prediction markets is that they work
We ran a study on over 2 million markets to evaluate their calibration. To our knowledge, this is the largest replicable study on this topic. Here are the results: 🧵
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My wife, @reardon_md, went viral with the below video... 2.3 MILLION views on Instagram so far!! 📷 Food is medicine and Dr. Erin is on the forefront of how and why that works.📷instagram.com/reel/DaTqfS6pG…
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As @emollick noted this morning, we’re not being ambitious enough with how we use LLMs. At their best, they represent “applied learning in the extreme.” That framing feels exactly right.
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Prof. Donald Knuth opened his new paper with "Shock! Shock!" Claude Opus 4.6 had just solved an open problem he'd been working on for weeks — a graph decomposition conjecture from The Art of Computer Programming. He named the paper "Claude's Cycles." 31 explorations. ~1 hour. Knuth read the output, wrote the formal proof, and closed with: "It seems I'll have to revise my opinions about generative AI one of these days." The man who wrote the bible of computer science just said that. In a paper named after an AI. Paper: cs.stanford.edu/~knuth/paper…
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This question is fun and the answer about mindset is fabulous. Reflect and tinker.
This is what an EXCEPTIONAL mindset thinks like and sounds like. So impressive from a 22 years old. Not only you CAN control what you think, and how you think it and why, but you SHOULD. See your mind as a skill and practice it as such.
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Adam Fleischhacker PhD, MBA retweeted
Replying to @BoringBiz_
People love to say that "smart" people fail...but a cardiologist just placed 3rd out of 13,000 at Anthropic’s hackathon. Smart + the right Initiative is insane leverage & where breakthroughs will come from...don't buy the hype. xitter.gq/BoWang87/status/202490…
After leading AI & Health at @UHN — Canada’s largest hospital network — for the past few years, this is the first time it genuinely feels different. A cardiologist just placed 3rd out of 13,000 at Anthropic’s hackathon. He built it between hospital shifts. In a week. An AI agent that follows patients home — reverse scribe, full history, devices, evidence — all in one place. A few years ago this would’ve taken a full team and months. Now? One doctor. That’s the shift.
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Adam Fleischhacker PhD, MBA retweeted
Claude Code isn’t just for writing code. Our new post shows how to use it as a lightweight agentic workflow library, going from messy ideas to working agents in a single session, without setting up a full framework first. landeranalytics.com/post/cla… #AIWorkflows
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Adam Fleischhacker PhD, MBA retweeted
Vibe coding is the new product management. Training and tuning models is the new coding.
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My wife’s new book just hit #1 in Amazon’s Diabetes books 🎉 I’m incredibly proud of her and the work she’s put into helping people take control of their health. Please support her entrepreneurial journey and grab a copy today🙏. Link in the comments 👇
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Interesting read on how the criteria by which we judge programming languages changes in the post-AI era.
A funny thing is happening: the more I build with agents, the less I want to use Python. I explore this in my latest "From Human Ergonomics to Agent Ergonomics" wesmckinney.com/blog/agent-e…
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Agree. AI makes breadth >> depth for most work: strong fundamentals + good judgment lets you mimic deep expertise when you need it. I can switch languages and produce code as if I’ve studied them for years.
Marc Andreessen explains future belongs to generalist in the AI era. Founders will need skills across 6–8 fields. Deep expertise still matters, but broad knowledge plus AI tools will be more valuable in most areas. Top CEOs already operate this way.
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{causact} 📦 v0.5.8 is on its way to CRAN. Learn computational Bayesian inference using this intuitive and visual #rstats package. Release includes a little intro vignette: cran.r-project.org/web/packa…
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Some songs don’t just remind you of youth, they bottle its most powerful emotions. “Candy Bars” by the brilliant @ConnorZwetsch is one of the most beautiful, nostalgic tracks ever made. It belongs on Spotify (used to be there). Pls help @ConnorZwetsch 🎶 soundcloud.com/zwetsch/candy…
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Figured it was legal stuff... sorry you had to deal with that. I’ll be first in line when Candy Bars returns to Spotify. If you ever feel like pulling a Taylor and re-recording, I’m all in for Candy Bars (Connor’s Version) 😄 Would love the audio in the meantime (ajf [at] udel [dot] edu).
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