Lower GI medical oncologist and medical adviser at Centre for Drug Discovery, Cancer Research UK.
London, England
Joined September 2015
- Tweets726
- Following753
- Followers467
- Likes6.5K
Dr Ravindhi Murphy retweeted
Strong @ChelwestFT team representation at #ESMO25 this year
Congratulations to Claire, Chloe & Kyle for their first ESMO posters
👊
Dr Ravindhi Murphy retweeted
This is probably the most important publication we have published for trainees and senior oncologists alike. This provides answers to almost every question you have about surrogate endpoints in oncology. This is a must-read for anyone with an interest in cancer trials. FREE!
Dr Ravindhi Murphy retweeted
Metastatic colorectal cancer. Third line and beyond. How to treat and what's the evidence. Nice review in @NatRevClinOncol
Dr Ravindhi Murphy retweeted
Attention #BCSP centres! We have created an SOP for the use of aspirin in #LynchSyndrome patients attending for #colonoscopy … please send me a message if you would like a copy - thanks! @stmarksbcsc @LynchSyndromeUK @StMarksGenomics @BowelsOfStMarks @NHSEngland
Dr Ravindhi Murphy retweeted
We have 2 trials of bispecific antibodies in lung cancer open and running @ChelwestFT
In fact, recruited the first patients in Europe to both of these
🦸
Bispecific antibodies (bsAbs) allow therapeutic applications that cannot be achieved using conventional antibodies. There are 14 bsAbs approved: 11 for cancer & 3 for non-oncology indications. This review summarizes this very active field, including bsAb signaling pathway modulators, tumor-targeted receptor agonists, ADC, bispecific T cell, natural killer cell & checkpoint inhibitors.nature.com/articles/s41573-0…
Dr Ravindhi Murphy retweeted
Liver transplantation + CTx vs CTx in unresectable CRC liver metastases
🔎TransMet randomised trial
@TheLancet
doi.org/10.1016/S0140-6736(2…
👉5-yr OS: 56.6 vs 12.6%
👉Recurrence after LTx: 72%
🧐Impressive study, impressive results
❗️LTx valid option in highly selected pts
@myESMO @EASLedu @ILCAnews #livertwitter
Dr Ravindhi Murphy retweeted
With the rising incidence of #colorectal #cancer (particularly in younger adults) this really is a ‘tidal wave’ of a response curve - can’t wait for the phase 3 RCT!
@kevinjmonahan @bowelcanceruk @bhmullish @PaulKMiddleton @ravindhi
Ecstatic and proud to share the NICHE-2 results, now published in @NEJM. Out of 111 pts, 95% had an MPR , and 68% a pCR after only 4 weeks of #neoadjuvant #immunotherapy. Grateful to the pts and colleagues who made this possible. @HaanenJohn
nej.md/3Ku4X0H
Dr Ravindhi Murphy retweeted
A smokefree future could mean tens of thousands fewer cancer deaths each year in the UK.
Read more about why today's tobacco Age of Sale legislation is important, including thoughts from our Executive Director @IanWalker_CRUK 👇 bit.ly/44h9eOl
#SmokefreeUK
Dr Ravindhi Murphy retweeted
I am at a terrific panel on women's health as part of my Corpus Christi College's truly inspiring 40 years of women in the college plus International Women's Day celebration. @ravindhi Speaking about the importance of @bowelbabe in increasing bowel cancer screening.
Dr Ravindhi Murphy retweeted
🎉 We are thrilled to welcome Gary Middleton as the new ECMC network lead.
We caught up with Gary to find out his plans for his first year, and his thoughts on some key challenges faced by the #Cancer research sector. Read his thoughts👉 rb.gy/ty7gfz
ALT Image of Professor Gary Middleton on the right, text reads: University of Birmingham, Birmingham ECMC, ECMC network lead. Also included ECMC logo
Dr Ravindhi Murphy retweeted
Cervical cancer will be almost eliminated in coming decades if HPV vaccination rates are high in children.
In England HPV vaccination coverage in schools is rising again but still below pre-pandemic levels. Please encourage children to get protected.
gov.uk/government/statistics…
Dr Ravindhi Murphy retweeted
I don't know who needs to know this more ( oncologist or patients or both ) But this is one of the best piece about cancer and diet misinformation in @TheLancetOncol.
Say NO to ketogenic diets , alkaline diets as treatment options.
Say NO to Quackery .
Dr Ravindhi Murphy retweeted
Great to see DETERMINE highlighted at @myESMO- it’s open for paediatric, teenage and young adult and adult cancer patients with rare cancers opening across @ECMC_UK supported by @CRUKresearch
The pioneering UK precision medicine trial DETERMINE being shared at #ESMO23 recruiting across the @ECMC_UK Network! #PrecisionMedicine @CRUKresearch @ECMC_Manchester @MatthewGKrebs
Dr Ravindhi Murphy retweeted
Once again #CancerWaitingTimes targets continued to be missed. Today’s figures are yet another snapshot of the challenges facing England’s cancer services and strong evidence for the Government that things need to change. cruk.ink/3Rl7Lli
In July 2023, the 62-day target of 85% was not met, with only 62.6% of people starting treatment for cancer within 62-days of an urgent referral.
These figures are among the worst on record and represent anxious delays for patients and indicate immense pressure on NHS staff.
People affected by cancer deserve more. Through strong leadership and proper funding, @SteveBarclay and the government have the power to put an end to unacceptable waits.
Later this year, @CR_UK will be publishing its #CancerManifesto, a blueprint for politicians on how to strengthen cancer research and transform cancer care and outcomes.
Dr Ravindhi Murphy retweeted
In the last 50 years, we’ve helped double cancer survival in the UK – but we’re not stopping there. We’re finding new ways to outsmart cancer, so more moments like these can happen. Your donations help fund trials and treatments to change the lives of people affected by cancer.
Dr Ravindhi Murphy retweeted
It really is good news to see this regulatory approval for Subcut atezo by @MHRAgovuk and also contemporaneous reimbursement approval by NHSE bit.ly/3RaUM5A based on IMscin001 data
#Media: The subcutaneous injection of our #cancer immunotherapy has received its first approval in Great Britain for some of the most aggressive cancers, including certain types of lung, bladder, breast and liver cancers. Learn more: spkl.io/60184Y2Ro
$RHHBY $ROG
Dr Ravindhi Murphy retweeted
I’m sad to say that IMHO, every NHS oncologist in any of the devolved nations of the United Kingdom will relate to this. This genuinely reflects the issues currently going on within NHS cancer services. Beautifully and eloquently described by @lucygoss. #NHS75 @SteveBarclay – at London, England
I’m an oncologist and I love my job. But I’m striking because I know first-hand that the NHS is failing our patients with cancer and I’m striking because I know first-hand that the NHS is failing its workforce. lucygossage.com/my-reasons-f… #ConsultantsStrike
Dr Ravindhi Murphy retweeted
🧵 (1/2)
We’re thrilled to launch our new five-year strategy. ‘On a Mission’ shows how we’ll:
👉ensure more people are diagnosed at the earliest stages
👉keep pushing for access to the best treatment and care
👉continue to support for anyone affected by a bowel cancer diagnosis
ALT On the left is a dark teal square. The text reads 'On a mission. Our strategy for making sure bowel cancer is diagnosed early to save lives.' On the right is a light teal circle. At the top of the circle is a yellow circle with a light bulb inside of it. The text to the right of it reads 'Goal 1: Increase awareness and understanding of bowel cancer.' Going clockwise around the circle, a quarter of the way down is another yellow circle. Inside that yellow circle is a alarm clock. The text beneath it reads 'Goal 2: Remove the barriers to people being diagnosed quickly and at the earliest possible stage.' At the bottom of the light teal circle is another yellow circle. Inside that is a graphic of a nurse. The text to the left reads 'Goal 3: Get the right treatment and care to every patient.' Three quarters of the way round the light teal circle is the final yellow circle. Inside that yellow circle is a heart. The text above reads 'Goal 4: Support people to cope better with bowel cancer.'
Dr Ravindhi Murphy retweeted
A fantastic resource
👏
All 🇬🇧 oncologists should use this
Cornerstone of good acute oncology care
Dr Ravindhi Murphy retweeted
How we let down people with cancer seen acutely in hospitals:
in a 2017 Merseyside audit 70% of people reviewed by an acute oncology service had died within 12 months.
My super colleague @AshlingLillis asks that we "See it, say it, share it"
macmillan.org.uk/healthcare-…
