Visiting Prof. Of Pathology, Sri Ramachandra Institute Of Higher Education & Research
Myrtle Beach, SC
Joined December 2013
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rajEndiran retweeted
Mesothelioma
Morphologic subtype is clinically significant
It should be reported for resections and biopsies
Dr. Chapel. Peritoneal Mesothelial Pathology
#ISGyP #pathology #PathX
rajEndiran retweeted
Epithelioid mesothelioma in the peritoneum:
• Can look morphologically similar to serous borderline tumor (pic 1)
• Can show calcifications similar to low-grade serous carcinoma (pic 2)
Warning: PAX8 and SOX17 are not reliable in this differential, they can be positive in up to ~15% of peritoneal mesotheliomas
Helpful stains: ER and PR are almost always negative in mesotheliomas
An ER/PR-positive proliferation is unlikely to be a mesothelioma
Dr. Chapel. Peritoneal Mesothelial Pathology
#ISGyP #pathology #PathX
rajEndiran retweeted
Hi all, Excited to share a recent study by @IASLC Pathology Committee that led to a long-awaited update in lung neuroendocrine tumor classification. Great joint effort by multiple institutions across continents!
jto.org/article/S1556-0864(2…
rajEndiran retweeted
Prostate cancer grading in 2026: Best Tips
1. Recognize the aggressive patterns (pic 1):
- Large cribriform
- Large sheet-like growth
- Anastomosing growth
- Cribriform
2. Do not worry about undercalling cases like pic 2. Outcome studies show these patterns are not associated with an aggressive clinical course
If you feel compelled to call pattern 4, minimize the amount. Studies have not found metastatic disease with these patterns.
Dr. McKenney. Prostatic Adenocarcinoma Grading: 2026 Update #USCAP #pathology #PathX
rajEndiran retweeted
***Intranodal thyroid inclusions***
1. Predominantly smooth luminal borders
2. Absence of nuclear pseudoinclusions
3. Nuclear diameter not larger that two times of an adjacent lymphocyte
4. Negative for BRAF, VE1, HBME-1 and galectin-3 IHC
They can coexist with metastatic PTC
Diagnostic criteria based on WHO 2020 Head and Neck Tumors
Dr. Hang #USCAP2026 #pathology #PathX #PathTwitter
rajEndiran retweeted
Pathology is not local. It is global! If you are interested in expanding your pathology knowledge, whatever your practice setting, check out the free curriculum and other resources that the Open Pathology Education Network has to offer. open-pathology.org/ #pathology
rajEndiran retweeted
Pathologic Diagnostic Algorithm for Trophoblastic Lesions
Based on clinical and morphologic features, trophoblastic tumors and tumor-like lesions can generally be readily distinguished. However, selected cases may pose diagnostic challenges, particularly in limited biopsy specimens and endometrial curettage samples. The following diagnostic algorithm may be used as a reference.
🤖 Made with AI
rajEndiran retweeted
This adenosquamous carcinoma appears to have arisen in the appendix. We were unable to confirm spread from another source (such as the lower anogenital tract).
rajEndiran retweeted
Numerous round, PAS-positive yeast forms surrounded by prominent, thick, clear halos, consistent with renal cryptococcosis.
#nephpath #renalpath #NephTwitter
rajEndiran retweeted
🧩 Prostate riddle
Continue exploring a rare tumor in the prostate.
Which component appears neoplastic, spindle or epithelial?
What would you consider in the differential?
#DxMindMap #ProstatePath #GUPath #PathTwitter @JHUpath
rajEndiran retweeted
Expanding the Histologic Spectrum of Oral Pseudoperineurioma: A Retrospective Study of 21 Cases
Hisham Alshuaibi, Shamim Neduvanchery, Sarah G. Fitzpatrick & Indraneel Bhattacharyya
rdcu.be/fAYxd
#HeadNeckPathol #HNPJ #HeadandNeckPath #Pathology #ENTPath #PathologyTweet
rajEndiran retweeted
A striking case of histoplasmosis. It really is nasty about mimicking Crohn's disease.
rajEndiran retweeted
"Cannon Ball Overload" - A case from today's sign-out, cell block and cytospins. (Metastatic breast ductal carcinoma, Pleural fluid)
rajEndiran retweeted
"In cytopathology, one signet ring cell may whisper, but a cluster always shouts malignancy." Hepatic hilar node with metastatic colonic adenocarcinoma, signet ring cell type. (FNA, Smear and Cell block).
