🚨 Latest #CoSci26 video release 🚨
Are Lean Mass Hyper-Responders born 🧬 or made 🏋️♂️?
Dr. Ben Bocchicchio @drbenbo dives deep into the LMHR lipid phenotype, questioning how diet, exercise, and genetics shape our cholesterol and cardiovascular health 📉💡.
Key insights covered:
🧬 Genetic predisposition vs. behavioral interventions
🧪 LPL & HSL enzyme activity in fat adaptation
📊 LMHR metrics & lipid energy transport
🧠 Future questions for metabolic health research
Check out the full talk and Q&A to explore the nuances behind the science! 👇🎬
youtu.be/MFgQuGawC28
🚨 Latest #CoSci26 video release 🚨
🥑 Thinking about going keto but worried about your cholesterol? 📊
In this #CoSci26 talk, machine learning researcher Dr. Terrance Boult unpacks "Calculator Confusion" 🤯 when measuring cardiovascular risk on a low-carb diet.
Key takeaways:
🫀 Keto can significantly lower projected heart risk despite total cholesterol going up.
🔍 Why popular models yield contradictory risk predictions.
🧪 How tracking HDL, blood pressure, A1C, and CAC scores gives a much clearer picture than standard lipid panels alone.
💻 Call for open-source risk calculators designed specifically for low-carb populations.
Test, don't guess! Watch the full video here ⬇️
youtu.be/RTE2Lsbg4oA
🚨 Latest #CoSci26 video release 🚨
Cardiovascular disease is the \#1 cause of death 💔, yet traditional 10-year risk calculators only give population averages—not individual answers. 📉
@lilyjohnstonmd breaks down why we need to move past guessing game risk panels and rely on direct imaging to spot arterial plaque early. 🔍✨
Key takeaways from her talk:
🧮 Why traditional risk calculators fail individual patients
🫀 The danger of silent heart attacks & strokes
🩺 CAC vs. CCTA vs. CIMT: Comparing direct imaging tools
🛡️ How early plaque detection enables targeted, life-saving therapies
Don't wait for a catastrophic event—learn how direct imaging can help you stabilize plaque and halt disease progression. 🫀🛡️
🎥 Watch the full presentation now: youtu.be/slgL9uEf3UY
🚨 Why has women's health research been overlooked for so long?
In this empowering #CoSci panel, medical experts & researchers tackle critical issues in metabolic health, hormones, and medical advocacy:
🧠 Hormones & Brain Health: The impacts of menopause and protective role of estrogen
🔥 Metabolic Adaptation: How weight loss & therapeutic carbohydrate reduction differ in women
🩺 Under-Researched Conditions: Lipedema, autoimmune health & postpartum depression
🗣️ Patient Advocacy: Navigating AI tools and speaking up with healthcare providers
🎙️ Featured Panelists:
• Dr. Annette Bosworth (Dr. Boz) @AnnetteBosworth – Internal Medicine Physician
• Dr. Lily Johnston @lilyjohnstonmd – Double Board-Certified Vascular & General Surgeon
• Siobhan Huggins @siobhan_huggins - Independent Metabolic Science Researcher
• Moderator: Dave Feldman @realDaveFeldman
💡 Take charge of your health journey with actionable science!
📲 Watch the full discussion here: youtu.be/ZDgz2jd-8FQ
Can exogenous compounds truly replicate the metabolic benefits of dietary ketosis? 🧠💡
In her #CoSci26 presentation, "Ketosis Mimetics: A Crash Tour," Amber O'Hearn @KetoCarnivore takes a deep dive into the physiological science behind exogenous ketones, precursor molecules, and pharmaceutical agents designed to mimic ketosis.
Key Insights:
🔬 Metabolic Bottlenecks: Unpacking rate-limiting steps, cellular energy pathways, and signaling mechanisms.
⚖️ Endogenous vs. Exogenous: Comparing holistic adaptations from dietary carbohydrate restriction against synthetic ketone supplementation.
📊 Therapeutic Realities: Evaluating safety, real-world efficacy, and clinical considerations for metabolic health applications.
Whether you are a metabolic health enthusiast, clinician, or researcher, this talk offers essential clarity on synthetic ketone elevation versus natural ketosis.
🎥 Watch the full video: youtu.be/KicSUoQhgFw
📍 For those in the St. Petersburg/Tampa/Clearwater area:
🎥 A screening of The Cholesterol Code will take place April 6th at the AMC Sundial in St. Petersburg, FL at 7:00pm
🎙️Join host Siouxie Boshoff, @ifixhearts, @AnnetteBosworth, @doctorkiltz, Dr. Nelson Vazquez, and @realdavefeldman for a Q&A following the film.
🎟️: gathr.com/events/d56608a8/th…
Proceeds from this fundraising event to benefit Citizen Science Foundation @realCSF.
Hope to see you there!
What an incredible weekend at CoSci 2026 🙌
We’re beyond grateful to everyone who joined us—attendees, speakers, and sponsors—for making this event so special. 💙 Your energy, curiosity, and passion created something truly meaningful… more than just a conference, but a community coming together to share ideas, learn, and connect.
Whether it was your first CoSci or you’ve been with us all three years, seeing the impact this event had on so many of you is what made it all worthwhile. ✨
Thank you for supporting the Citizen Science Foundation @realcsf and being part of this journey with us. 🙏
#CoSci26 #CitizenScience #ThankYou #Gratitude #Community #Science #MetabolicHealth #LasVegasEvents #Finale
Citizen Science Foundation retweeted
Dave Feldman at #CoSci Las Vegas
100 Hearts.
@realDaveFeldman addressed the retraction of the LMHR Coronary Plaque Progression (CCTA) study and explained what led to that decision.
A candid look at the data, the analysis, and the reasoning behind pulling the paper, including a surprise twist later.
If you want the full story and where this research goes next, the conference recordings are worth it.
@realCSF
Citizen Science Foundation retweeted
Dr. Shawn Baker at #CoSci, Las Vegas.
He says: joints need load.
Strength, full range of motion, progressive loading.
“Bouncing on a rebounder is not enough.”
@SBakerMD @realDaveFeldman @realCSF
Citizen Science Foundation retweeted
Siobhan Huggins at CoSci, Las Vegas.
Lymphedema is a devastating and often lifelong side effect of cancer treatment.
Most of the effort goes into managing it after it appears.
Siobhan is asking a different question: could metabolic health before treatment change the risk?
Her hypothesis is that insulin resistance may play a role, and metabolic therapies such as ketogenic diets might help reduce that risk.
@siobhan_huggins @realDaveFeldman @realCSF
Citizen Science Foundation retweeted
Louis Burns on stage at #CoSci Las Vegas.
All Models Are Wrong: Reconciling Carbs vs Calories
The carbs vs calories debate may exist because the two models explain different things.
Calories help explain body weight and composition.
Carbohydrates help explain metabolic health.
Both sides may be right, just talking about different problems.
@realDaveFeldman @realCSF
Citizen Science Foundation retweeted
Jenna Ericson on stage at #CoSci Las Vegas.
Reactive Oxygen Species and Physiological Insulin Resistance
Her model: insulin resistance may begin in the mitochondria.
When excess electrons back up in the electron transport chain, reactive oxygen species are produced, which can blunt insulin signaling.
The fuel you burn may determine how much of that stress your cells generate.
@realDaveFeldman @realCSF
Citizen Science Foundation retweeted
Dr. Stephen Hussey on stage at #CoSci Las Vegas.
Atherosclerosis: Are We Asking the Wrong Question?
For decades the focus has been on cholesterol, LDL, ApoB, Lp(a).
But plaque does not form in the bloodstream alone. It forms in a much more complex environment.
Dr. Hussey’s point: after decades of narrowing the question to lipids, maybe it is time to start asking different questions.
@DrStephenHussey @realCSF @realDaveFeldman
Citizen Science Foundation retweeted
Emily Harari on stage at #CoSci, Las Vegas.
How to actually personalize medicine
Most lab reference ranges are built on population averages.
But none of us are the “average.”
Emily talks about microsampling. Small, simple blood samples people can collect at home and send in regularly.
The idea is to build your own baseline over time, instead of comparing yourself to a population range that may not fit you at all.
@realDaveFeldman @realCSF
Citizen Science Foundation retweeted
Dr. Annette Bosworth on stage at CoSci, Las Vegas.
Sequenced Metabolic Repair
@AnnetteBosworth presents a striking case of severe metabolic dysfunction. Type 2 diabetes, prior cancer treatment, obesity, edema. HbA1c 10.9%. Triglycerides 547.
Standard approaches failed. Even a 21 day water fast did not produce meaningful ketosis. Two years of high dose tirzepatide had no effect.
Dr. Boz then shifted the strategy: repair metabolism first.
Nutritional ketosis to restore mitochondrial function, then reintroducing GLP-1 therapy at a tiny micro dose.
After 90 days: HbA1c down to 6.0%, 44 lbs lost, edema resolved, metabolic flexibility restored.
@realDaveFeldman @realCSF #CoSci
Citizen Science Foundation retweeted
The Cholesterol Code documentary panel at CoSci, Las Vegas.
Following yesterday night’s screening at The Beverly Theatre.
Moderated by director Jennifer Isenhart, with Matt Baszucki, Robyn Dobbins, and Eric Rodgers, all featured in the film.
The conversation pulled back the curtain on the stories behind the documentary and the people whose experiences helped shape it.
@Metabolic_Mind @DrEricRodgers @matthewbaszucki @robynrdobbins @realCSF @realDaveFeldman
Citizen Science Foundation retweeted
At #CoSci in Las Vegas @DominicDAgosti2
Brain Energy and Brain Injury: Considerations for Older Adults
We tend to associate traumatic brain injury with athletes or the military. In reality, it is most common in older adults.
After 65, even relatively small head impacts can have serious consequences.
Dr. D’Agostino framed brain injury as a problem of brain energy and resilience, not just the impact itself.
Protecting brain metabolism, maintaining strength and balance, and supporting metabolic health may reduce risk and improve recovery as we age.
@realDaveFeldman @realCSF
Citizen Science Foundation retweeted
“I would have had to take that cocktail of meds for the rest of my life just to stay stable.”
Matt Baszucki at #CoSci
After years of manic psychosis, hospitalizations, and a bipolar diagnosis, he says ketogenic therapy changed everything.
“Once I fed my brain the right foods, everything fell into place. My manic episodes stopped.”
Now symptom-free after adopting a ketogenic diet under the care of @ChrisPalmerMD.
@janellison @Metabolic_Mind @realDaveFeldman @matthewbaszucki
Citizen Science Foundation retweeted
Kicking off Day 3, the final day at CoSci.
Dr. Eric Westman: A review of the clinical research on keto diets. Where do we go from here?
Keto may be best known as a weight loss diet, but the research goes far beyond that.
Dr. Westman reviewed decades of clinical studies on low carb and ketogenic diets and looked at the evidence through an evidence based medicine lens.
The big question: where should the next generation of clinical research go?
@drericwestman @realDaveFeldman @realCSF
