Parasitologist | McCulloch Lab @ University of Glasgow
Glasgow, Scotland
Joined December 2014
- Tweets226
- Following101
- Followers131
- Likes354
Marija Krasiļņikova retweeted
Pleased 2 share our new article: single-molecule replication mapping in Leishmania using DNAscent.
We show widespread stochastic origin firing and insights into genome variability.
cell.com/cell-reports/fullte…
Big thanks to Mike Boemo
Marija Krasiļņikova retweeted
32 T2T!!!
Happy to share our preprint showing the molecular karyotype of #Trypanosomacruzi
@GonzaloGreif @fdiazviraque #MariaLChiribao @CarlosSanz22
@PacBio HiFi
biorxiv.org/content/10.1101/…
Marija Krasiļņikova retweeted
Excited to share our latest work on R-loops and RNAse H1, exploring their roles in genome replication timing and stability. It’s now published!
nature.com/articles/s41467-0…
@McCulloch_Group @emmabriggs6 @scotomorph @MarquesCata
Marija Krasiļņikova retweeted
We're pleased to share a new paper @UofGSii @WCIPGLASGOW led by @scotomorph @MarquesCata where we show that T. brucei DNA replication dynamics reflect structural and functional compartmentalisation of the genome. Well done Marija!
doi.org/10.1038/s41467-025-5…
Marija Krasiļņikova retweeted
Drs Stephen Larcombe @jane_munday & @rmc9z highlight @MonicaMugnier & colleagues’ @Nature article on tissue spaces as #reservoirs of #AntigenicDiversity for #Trypanosoma #brucei. @SBSatEd @WCIPGLASGOW @UofGSii @JohnsHopkinsMMI @JohnsHopkinsSPH #Trypanosome
cell.com/trends/parasitology…
Marija Krasiļņikova retweeted
Are you interested in genome maintenance, organisation and replication?
We have a BBSRC-funded PhD position to use multi ‘omics’ approaches to tackle this problem! @McCulloch_Group @UniOfYork @YBRI_UoY findaphd.com/phds/project/ma…
Marija Krasiļņikova retweeted
Fancy a sneak peek into Leishmania’s unusual DNA replication programming? At @McCulloch_Group we used D-Nascent to map origins & forks at the single-molecule level, revealing novel, abundant replication initiation events across its plastic genome. See links below👇
Marija Krasiļņikova retweeted
Very happy to share new work @UofGSii @WCIPGLASGOW led by @jezielbqi describing very abundant, previously undetected DNA replication activity in Leshmania using DNAscent, a technique developed by @CNieduszynski Great work, Jeziel.
shorturl.at/G7uRm
Marija Krasiļņikova retweeted
Funded PhD available with us, @martllewellyn and James Cotton @UofGSii @UofGSBOHVM @WCIPGLASGOW to study genome replication and (in)stability across diverse kinetoplastids. Applications (via FindaPhD) taken from Nov 1st - Jan 12th. Enquiries welcome.
tinyurl.com/mfz4yh3k
Marija Krasiļņikova retweeted
Our new study led by @scotomorph @MarquesCata We used Nanopore sequencing to map DNA replication across the whole T. brucei genome, revealing partitioning that drives instability for immune evasion @KathrynCrouch81 @emmabriggs6
biorxiv.org/content/10.1101/…
Marija Krasiļņikova retweeted
We’re pleased to share a new study led by @jezielbqi describing how R-loops and RNase H1 dictate chromosome size-dependent DNA replication timing and genome stability in Leishmania @emmabriggs6 @scotomorph @MarquesCata
biorxiv.org/content/10.1101/…
Marija Krasiļņikova retweeted
We're very happy to share this study in @NAR_Open, led by @mggrzl and @emmabriggs6, describing R-loop interactors in T. brucei, including new functions in immune evasion. Great work, Mark, and thanks to all authors @UofGSii @WCIPGLASGOW
rb.gy/rnu7w
Marija Krasiļņikova retweeted
Joining us for our next meeting on the 29th March? Great! Register on Eventbrite so we know how much food and drink to buy! Details of talks will be available after the call for speakers deadline, which is next week. *Our flash talks are now full!*
eventbrite.co.uk/e/ion-bru-m…
Marija Krasiļņikova retweeted
Come and join us! 3 year, Wellcome-funded research assistant/associate position to study genome replication and (in)stability in trypanosomes and/or Leishmania @WCIPGLASGOW @iiiglasgow Closing date for applications May 4th 2022. Enquiries welcome.
bit.ly/3r7JS2Q
Marija Krasiļņikova retweeted
Interested in using #evolution & #bioinformatics in #virus #HIV research? We've a #PhD project at @CVRbioinfo with @mlcotten13 at @UVRIug. Join our WT Integrative Infection Biol programme. Open and *fully funded for international applicants*. Please apply! ow.ly/nLZY50wY9is
Marija Krasiļņikova retweeted
PhD position available with @BiottofnI and @KeithRMatthews to use scRNAseq and unravel transmission biology in trypanosomes bit.ly/2sGv1kw
Marija Krasiļņikova retweeted
Chromosomal rearrangements and loss of subtelomeric adhesins linked to clade-specific phenotypes in Candida auris biorxiv.org/cgi/content/shor… #biorxiv_genomic
Marija Krasiļņikova retweeted
We couldn't agree more and have our Hi-C maps on the office wall.
Left panel: the unscaffolded T. brucei genome.
Right panel: the scaffolded genome.
Hi-C data is beautiful. Need to remember to print out the @siegel_lab figures for T. brucei to go on the office wall
Marija Krasiļņikova retweeted
Loving the slides from Florian Erhard, discussing core features of CMV-induced regulation in single cells!
#evbc2019 @robertson_lab @EVirusBioinfC @CVRinfo
