frontier biotech is so fast and messy you can barely keep up between the peptides, AI designing drugs, gene editing, personalized cancer vaccines and the FDA trying to figure out how to regulate all of it, the signal keeps getting lost so we decided to make it easier for you every month, you get a newsletter episode breaking down: → the breakthroughs actually worth knowing about → the papers and research moving the frontier forward → the companies building Humanity 2.0 → new Superhuman Fund investments → portfolio updates → fresh Accelerate Bio episodes think of it as the monthly changelog for Humanity 2.0 less noise, more bio/acc signal. link below.

Eli Lilly just sued 6 companies for selling black market retatrutide and this whole story is bullshit and I'll tell you why now, i'm not saying black market sellers are innocent they're not, unregulated foreign manufacturers and fake "research-use only" labels are genuinely dangerous but it's bullshit because Lilly is framing this as patient protection when the real story is a $700B company that let a 14,000+ listing black market grow for years and only moved once it started cannibalizing their own sales if patient safety were actually the priority, the verification infra would've existed before the lawsuits what we're seeing is just a cleanup with a press release so here's the actual question for everyone reading this: why does it take a lawsuit for a company this size to notice a supply chain problem a startup could've flagged two years ago?

everyone's mad that Kailera's $718.8M IPO was built on Chinese-discovered drugs wrong thing to be mad about the US never had to invent everything to win it never invented the assembly line either, it just perfected manufacturing at a scale nobody else could match I don't think Kailera failed to invent They straight up went for the harder part, which is taking someone else's early science and proving it could survive US capital markets, US trial rigor, and a Nasdaq listing the lab gets a footnote, the company that ships it gets the market. pick which one you want to be mad about. bio/acc

it's 2026 and the majority of digital health VC dollars is still going to symptom management only a small slice touches actual prevention and restoration, wearables, sleep, recovery meanwhile consumers are already spending real money out of pocket moving toward that smaller slice the market's already voting capital hasn't finished counting the ballots if you're investing in that layer, DM me bio/acc

frontier bio is ripping this is july 2026 alone, let me put you on: - FDA committee just voted to legalize compounding for 6 grey market peptides, BPC-157, KPV, TB-500, MOTS-c, Epitalon, Semax - new CRISPR technique (KNIT) inserts up to 10kb of DNA with zero cuts, 89% efficiency - Casgevy, the first ever CRISPR cure, expanded to kids as young as 2 - a hep B therapy directly eliminated the viral reservoir in a human liver for the first time ever - one CRISPR treatment cut hereditary angioedema attacks by 87% - Anthropic launched Claude for Science, then quietly started running its own internal drug discovery lab - Fate Therapeutics cleared to test off-the-shelf CAR-T with 13 gene edits, no chemo required - Colossal reportedly raising at $20-30B without a single extinct species back yet this is just one month welcome to biosummer 2026 if you're investing in this layer, gene editing infrastructure, peptide validation and supply chain, biological age diagnostics, AI-native drug discovery, DM me.

Can someone help me make sense of this? NewLimit is worth $3.1B... and they haven't even started human trials yet. Meanwhile, there are public biotechs with Phase 1 data, patients dosed, and years of clinical work...worth less. So what exactly is the market pricing? Definitely not today's data - tomorrow's platform. AI, Epigenetic reprogramming, Brian Armstrong, Jacob Kimmel, Founders Fund That's the bet. Whether it's brilliant or completely wrong is probably one of the biggest questions in biotech right now. If you're funding the future of biology, let's talk. bio/acc.

Billions are pouring into AI drug discovery. Zero approved drugs. But that's about to change. Retro Bio Head of Applied AI @ricomnl explains it all. 00:00 - Zero AI Drugs Approved 05:05 - Retro’s 50x 09:38 - The AlphaFold Moment 13:47 - Black Box Data 21:23 - The Ladder: Proteins to Cells 25:02 - Are Virtual Cells Overhyped? 32:53 - Hitting the Clinical Wall 35:58 - AWS for Biotech 46:16 - The Real Inflection Point 49:30 - The Anti-Scaling Law 54:25 - AI Co-Scientists 1:03:32 - Real vs hype

99.99th Percentile IQ Embryo Selected. What does it all mean? @JonathanAnomaly explains how polygenic embryo selection is moving from science fiction into reality. And why the biggest barrier may no longer be technology, but culture. 00:00 - Viral IQ Embryo & Eugenics 07:10 - PGT Adoption 11:20 - Will Governments Ban This? 15:30 - Fertility Decline & Genetic Selection 21:30 - How Accurate? 28:50 - The Heritability Ceiling 35:20 - Autism, Neurodivergence 37:30 - A Genetic Vaccine 42:40 - PGT Skepticism 48:05 - Dangers of Pleiotropy 55:05 - The Adoption Curve 58:30 - Future of IVF 1:06:00 - Pronatalists & The Future 1:11:10 - Embryo Selection vs Editing 1:17:30 - Building Better Humans

SUPER IMPRESSIVE: pancreatic cancer just got its most meaningful survival improvement daraxonrasib vs chemotherapy: - 13.2 months median survival vs 6.7 months - 53% of patients alive at 12 months vs 17% - hazard ratio 0.40. that means a 60% reduction in the risk of death but here is what's even more impressive RAS mutations drive 30% of all human cancers. lung, colon, pancreatic. the most common and the deadliest. RAS has been called undruggable for 40 years. Revolution Medicines just drugged it an oral pill. once daily. FDA Breakthrough Therapy designation and it's being presented at ASCO this week that is what happens when you combine precision genomics, targeted therapy design, and the audacity to go after the target everyone said was impossible the era of cancer as a death sentence is soon ending bio/acc

you think the Enhanced Games is just a sporting event for enhanced humans? it's actually the opening ceremony of a new world order the normalization campaign for human 2.0 - what if sex was more pleasurable? - what if you could look better at 60 than you did at 30? - what if you never got sick again -what if your mind worked at a frequency most people never reach? - what if happiness was not a mood but a baseline? -what would happen if you took psychedelics before choosing who to marry, where to live, and what to do with your life that is the actual conversation happening in Las Vegas tonight a few days ago I sat down with Christian Angermayer, the man who put $100M into psychedelics before anyone else would touch it. the man behind ENHANCED GAMES. link below

Vanity drugs make more money than AI. Billionaire investor @C_Angermayer explains why peptides, GLP-1s, psychedelics, longevity & performance enhancement are exploding. And why optimizing the human body and mind will become the next trillion-dollar industry. 0:00 - Human Enhancement Is Here 06:38 - Trans vs Looksmaxxing 11:12 - Enhanced Games 22:32 - Next Red Bull 25:48 - Going Too Far 32:18 - Psychedelics Unlock 37:49 - Universal Happiness 43:30 - MDMA x Marriage 46:27 - 12 vs 2h Trips 54:18 - Trump, Ibogaine, Addiction 1:00:22 - Sex, Pleasure, Female Orgasm 1:10:04 - Vanity Drugs & Future

>be me >interview the Harvard professor >ask about gene editing humans >"we're already doing it" >what about germline editing? >"it's the cleaner solution" >ask about modified humans walking among us >"they're already here" >how far away sir? >"tomorrow" >ask why we haven't >[redacted] >shift gears >"US biotech losing to UAE?" >he nods >ask about the next dire wolf moment for humans >"our ancestors wouldn't [redacted]" >thank George, banger episode >I post the episode on X >algorithm nukes it >cry >WTF? link below

I interviewed @geochurch and learnt we're already gene editing humans. You just haven't noticed. 0:00 - Gene Editing Mammals → Humans 8:36 - Germline vs Somatic 14:56 - Modified Humans Are Already Here 18:50 - Enhancing Healthy Humans 25:00 - Aging Therapies vs Cognitive Enhancement 30:20 - Embryo Selection 38:10 - Is US Losing To UAE? 42:33 - Biotech Failures 49:31 - Next Dire Wolf Moment 54:21 - AI x Science 1:02:07 - Synthetizing Entire Genomes

what to do now?

I interviewed @aubreydegrey on why neither billionaires nor AI will solve aging. And why a single mouse breakthrough could be the ChatGPT moment for longevity. 0:00 - Longevity Field 20 Years On 08:58 - Are Billionaires Getting It Wrong? 17:13 - Bryan Johnson vs Peter Thiel 23:42 - ChatGPT Moment for Longevity 28:52 - Biological Age vs Lifespan 34:44 - Influencers Will Save Us 39:36 - AI x Science Breakthroughs 48:14 - Sam Altman on Aging 53:39 - Genesis Mission 56:45 - Systems Will Collapse 1:08:55 - GLP-1s & Human Enhancement

If you want the longform version (2hr interview w Jesse), check - accbio.xyz/rabbit1