Medicinal chemist, Ologist, Studies marine natural products and biosynthesis in animals. Not so fueled by caffeine anymore. 🇵🇭 🇺🇸🇩🇰
Copenhagen, Denmark
Joined April 2016
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Here’s the Ologies episode I did with @alieward and Sabah Ul-Hasan on cone snails. We talked about venoms, Jurassic Park, Rembrandt, microbes basically everything about the cones. So cool to be on the show! Thanks for having me talk about my favorite snails 🐌 @Ologies
CONE SNAIL VENOM. Weirder than I imagined. It can kill you dead, but also save your life? Scientists have even used it to make a painkiller 1000x more powerful than morphine. #Conotoxinologists Dr. Sabah Ul-Hasan & @yeahhh_wa explain it all:
alieward.com/ologies/conotox…
Joshua Torres retweeted
A very nice piece covering our story on the unusual glucose-lowering hunting strategy used cunningly by the fish-hunting cone snail, Conus geographus. Check it out!
Cone snails in the tropical waters of Palau have a secret weapon.
Researchers (@UUtah) found that one cone snail deploys insulin- and somatostatin-mimicking toxins that crash fish blood glucose levels.
bit.ly/3CrY5A9
Joshua Torres retweeted
Job ad for research tech or lab manager is up!
cu.taleo.net/careersection/2…
Experience with mouse handling and mouse colony management will be given preference. If you think glia are cool and want to learn about glial epigenetics, while setting up a new lab, join us! #newPI #glia
My favorite #NobelPrize post of all time 😅
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Joshua Torres retweeted
Science is built on trust. What happens when someone destroys it?
My first feature for @_TheTransmitter investigates the emotional and existential fallout for one lab in the aftermath of a misconduct case.
thetransmitter.org/science-a…
Joshua Torres retweeted
On Thurs Sept 12, Helena Safavi @SafaviLab will give her tenure talk entitled "Insights from the Biology, Behavior, and Evolution of Venomous Animals for Drug Discovery." 12pm at HSEB Alumni Hall!
Presenting Dr. Sophie Heiden Laugesen Ph.D.! Congratulations, Sophie! Your cone snail family is proud of you! @SafaviLab 🐌 🎉 🎈💥
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Conotoxins that disrupt glucose signaling in preys! Another amazing work from the Safavi Lab!
Excited to share our latest story on how fish-hunting cone snail uses a combination of weaponized insulin and somatostatin-like toxins to disrupt glucose level in its fish prey 🐚⚡️🐠🍬
Check out our paper and animation to learn more:
nature.com/articles/s41467-0… @NatureComms 🧵1/5
Joshua Torres retweeted
Psychedelics don't quite fit into the standard way we evaluate drugs—randomized double-blind trials—as you can't really mistake MDMA for a placebo.
Are psychedelics the problem? Or does our gold standard need updating?
My first for @TheAtlantic
theatlantic.com/health/archi…
Joshua Torres retweeted
A unique cuticular hydrocarbon from the springtail Heteromurus nitidus. This new terpene type, a prenylated geranylated diterpene, highlights differences between Collembola and more advanced insects. See our article in J Nat Prod. doi.org/10.1021/acs.jnatprod…
Joshua Torres retweeted
We show the discovery of the #conopeptide Fj1, a selective agonist of the #somatostatin receptor 4 from the transcript of C. fijisulcatus, and shows potent #analgesia in mouse models of #postoperative and #neuropathic pain.
Huge thanks to all co-authors (too may to list in tweet)
Venom-inspired somatostatin receptor 4 (SSTR4) agonists as new drug leads for peripheral pain conditions biorxiv.org/cgi/content/shor… #biorxiv_pharma
Joshua Torres retweeted
Having observed that grad students are taught almost everything about science and engineering except how to pick a problem, me and Chris Walsh started a class at Stanford on the topic in 2019 (BIOE 395). What follows are eight lessons from the course. 3/53
Joshua Torres retweeted
Ichi-Ei Ishigen and co-workers present the Retro-Suzuki Reaction: a method of cleaving biaryl C-C bonds to give aryl halides and boronic esters. This could completely revolutionise cross-coupling chemistry!
Full text PDF: jabde.com/wp-content/uploads…
Cool beans!!
17 years in the making..
We are super excited to finally achieve alcohol-alcohol cross-coupling enabled by the powerful SH2 radical sorting! Great work Jerry, Nick, Jay, James, Colin and Robert. Big shout out to our collaborator Jesus from Janssen Spain.
science.org/doi/full/10.1126…
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Joshua Torres retweeted
We are seeking an experienced and highly motivated Senior Metabolic Engineering Scientist to join our Strain Engineering Team. The successful candidate will be a key contributor to our precision fermentation platform
Apply here: biosyntia.com/join-us#op-611…
Joshua Torres retweeted
A study reveals that a large proportion of genes can be predicted. These findings carry implications for understanding evolutionary dynamics in prokaryotic genomes.
In @physorg_com : ow.ly/mEnO50QpITR
Read the full article in PNAS: ow.ly/I9oA50QpITQ
ALT The coincident relationships of predictable genes and their predictors. The nodes are gene families, or groups of gene families with the same PAP, and the edges are coincidence relationships with the arrow pointing at the node whose presence is predicted by the other.
Joshua Torres retweeted
For anyone still “standing with Israel” or trying to inject false nuance into the Israeli genocide of Palestine, this thread is for you. These are the things you won’t be shown on the western news. Look at them now. It’s not too late to adjust your perspective.
Joshua Torres retweeted
Post doc positions available @cphglyco One position is for a unique and exciting project on glycans and body weight biology together with @ClemmensenC DEADLINE OCTOBER 1st employment.ku.dk/faculty/?sh…
One of the postdoc positions advertised by @kattesch revolves around a super exciting and close collaboration with our lab at the @Metabolcenter -> glycomics & body weight biology. APPLY!
