Investor, econ wonk, Acct Prof., Lawyer, xCEO, Biotechs John 3:16 "Likes" not agree. LTBH & trading, Options. LQDA,OCUL,TGTX,HROW,ORCL,URGN,NFLX,CHTR

St Louis, MO
Joined March 2009
Europe used to have a GDP 90% of America. Now it's 65% & heading to 50%. The US is about 1.6× higher on a per-person basis than Canada. That used to be 1.4x just a decade ago. Nearly every country is falling behind the USA.
JPMorgan CEO Jamie Dimon warns Europe is falling dangerously behind America economically… and blames anti-business, anti-investment, and anti-innovation policies. 🇺🇸🇪🇺 “If you don’t believe me, go to Europe, folks. Europe used to have a GDP per person of 90% of America’s. It’s now 65%. It’s on its way to 50%. That will jeopardize the health of Europe itself over time. And it’s all anti-business, anti-investment, anti-innovation. They kind of know it. If they don’t fix it—and we should help them fix it, because Europe matters—it’s really bad for the Western world, too. We should do it wisely.” Europe shift over the past three decades has proven decimating for their economy. Aging population forces mass immigration in order to maintain adequate growth. Crazy regulation and bureaucracy slows innovation and investment… forcing the economy further down. At the same time, the United States has pulled ahead exponentially and will continue to do so. Europe is struggling.
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zipjet retweeted
The Weekly #7 10/27 we're live, things are back on the up. Lots of new positions, probably the least concentrated I've been in a long time. $LQDA followers some good news, I am back long amongst plenty of other names. seedy19tron.substack.com/p/t…
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This is the Hillary Clinton I know. As some of you know, I was the Air Force Military Aide for Bill Clinton, lived in the White House, traveled everywhere they traveled, and carried the “nuclear football.” As such, I was always in close proximity to both Bill and Hill. Among the military who served in the White House and the professional White House staff, the Clinton administration was infamously known for its lack of professionalism and courtesy, though few ever spoke about it. But when it came to rudeness, it was Hillary Clinton who was the most feared person in the administration. She set the tone. From the very first day in my assignment. When I first arrived to work in the White House, my predecessor warned me. “You can get away with pissing off Bill but if you make her mad, she’ll rip your heart out.” I heeded those words. I did make him mad a few times, but I never really pissed her off. I knew the ramifications. I learned very quickly that the administration’s day-to-day character, whether inside or outside of DC, depended solely on the presence or absence of Hillary. Her reputation preceded her. We used to say that when Hillary was gone, it was a frat party. When she was home, it was “Schindler’s List.” In my first few days on the job, and remember I essentially lived there, I realized there were different rules for Hillary. She instructed the senior staff, including me, that she didn’t want to be forced to encounter us. We were instructed that “whenever Mrs. Clinton is moving through the halls, be as inconspicuous as possible.” She did not want to see “staff” and be forced to “interact” with anyone. No matter their position in the building. Many a time, I’d see mature, professional adults, working in the most important building in the world, scurrying into office doorways to escape Hillary’s line of sight. I’d hear whispering, “She’s coming, she’s coming!” I could be walking down a West Wing hallway, midday, busier than hell, people doing the administration’s work whether in the press office, medical unit, wherever. She’d walk in and they’d scatter. She was the Nazi schoolmarm and the rest of us were expected to hide as though we were kids in trouble. I wasn’t a kid, I was a professional officer and pilot. I said “I’m not doing that.” There was also a period of time when she attempted to ban military uniforms in the White House. It was the reelection year of 1996, and she was trying to craft the narrative that the military was not a priority in the Clinton administration. As a military aide, carrying the football, and working closely with the Secret Service, I objected to that. It simply wasn’t a matter of her political agenda; it was national security. If the balloon went up, the Secret Service would need to find me as quickly as possible. Seconds matter. Finding the aide in military uniform made complete sense. Besides, what commander in chief wouldn’t want to advertise his leadership and command? She finally relented because the Secret Service weighed in. The Clintons are corrupt beyond words. Hillary is evil, vindictive, and profane. Hillary is a bitch.
Barf. I know you both. Hardly. 🤣🤣🤣 The stories I’ve told…and the stories I could tell. 🤔
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🚨 HOLY CRAP! Bobby Kennedy is dropping HARD TRUTHS about the REAL "genocide" in the Middle East, and it's not Palestine: "What happened to the Christians? There were millions and millions of Christians. Those were all Christian countries. Egypt was a Christian country. Libya was a Christian country. Algeria was a Christian country. Iraq was a Christian country. Lebanon was a Christian country in 1948." "The Christians have been expelled." "THESE are genocides, and they have a genocide that is envisioned in some of the chartered documents. It's in the lectures of the imams. It's in the sermons!" RFK dropped similar stats about Jewish populations in the region. Nearly 900K Jews were driven out of Arab nations after 1948, Iraq's ancient Christian community was decimated by over 80%, and Lebanon went from a Christian-majority nation to a fester for Hezbollah The media refuses to acknowledge THAT. Yet today, people like Abdul El Sayed think AMERICA is the evil one for trying to prevent Iran's Islamists from getting a NUKE Look what their own playbook orders them to do! Trump did the right thing 🇺🇸
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zipjet retweeted
BREAKING: Riots have completely engulfed Bilboa, Spain. What has Europe done to itself?
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According to this chart re exit polls, Netanyahu leads big. One short of 61. But could change slightly although not in a significant way as I’m told.  This is huge.
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HORRIFYING: New footage shows Boko Haram Islamic jihadists in Africa massacring Christians with machetes. This year alone, more Christians have been killed in Nigeria than Palestinians in 3 years of war. Don’t stop talking about the real genocide of Christians in Nigeria.
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zipjet retweeted
$OCUL Just noise for now but chatter Sanofi may be coming back I still think $MRK buys the company
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zipjet retweeted
The single most important thing you can do security-wise is to lock your mobile account and turn on SIM lock at your carrier. (Also do it locally on your phone). Summary from AI: Turn on the specific locks for your carrier (these block unauthorized SIM/eSIM swaps and/or number ports):AT&T: Wireless Account Lock (blocks SIM changes, ports, upgrades, and more). Use the myAT&T app on an active device. Verizon: Enable both SIM Protection (blocks SIM/device changes) and Number Lock (blocks ports). Use the My Verizon app or website under security settings. T-Mobile: Enable SIM Protection and Port Out Protection. Available in the T-Life app or on the website (often as add-ons per line).
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zipjet retweeted
I've now conversed with 4 "professionals" with either/both finance/biotech background. Highly respected and knowledgeable who want to remain anonymous. Here is the common feedback in accordance to their knowledge: 1. $LQDA Yutrepia is superior. 2. PAH alone is worth $50 a share ($5B). 3. PH-ILD market is not fully gone. Overlap of patients is probably around 50%. 4. Doctors at major centers will do absolutely anything and everything for their patients. 😉 5. L606 is different than TPIP. Both can exist and be successful. Different patient group for each. Early stage to mild PAH will probably start TPIP while more advanced PAH and all PH-ILD patients will be on L606 or Yutrepia. More trepostinil is better. Nebulizer has lower cough. Twice a day is not a burden, just right. 6. L606 has not been given any evaluation. More of "No loss to revenue if TPIP is successful". 7. SSc-RP and PH-COPD could chance everything. Yutrepia high dose could shine in both studies where other drugs can't compare. For SSc-RP you need to put a lot of trepostinil in the body, Yutrepia has a good chance. PH-COPD is all about cough management and Yutrepia is once again best at high doses over nebulizer. L606 would be optimal. 8. Fair value is somewhere between $70-85 right now and over $100 if SSc-RP or PH-COPD hits.
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Cool!!!
I captured this video in my lab to show the power of medicines called T-cell engagers. Left: T cells move in and out of a cancer tumoroid, largely ignoring it. Right: Add a T-cell engager, and the T cells attack. Once they recognize their targets, they tear through the tumor.
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zipjet retweeted
$LQDA with the absolute best PAH and PH-ILD drug on the market. You can add other indications soon enough. Lots of IV and Oral patients left to convert.
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Racism: Now You See It, Now You Don’t Last Friday a 39-year-old gunman named Kevin T. went on a shooting spree in two suburbs of Paris (Trappes and La Verrière), killing one person and wounding seven others. The murderer reportedly selected persons of color as his targets. French President Emmanuel Macron said that the attack was the first terrorist act in France committed for reasons of skin color or religion. The photo at the top of this post shows the aftermath of the massacre that killed 90 people at the Bataclan concert hall in Paris on November 13, 2015. The killers were mujahideen for the Islamic State, and targeted their victims for religious reasons, i.e. because the latter were not Muslims. However, the incident evidently does not count as an attack “for reasons of skin color or religion”. As we all know, Muslims and/or brown people who kill white non-Muslims can never be said to have racist or religious motives. Those are just the rules of the game, even though they make no sense.
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Many of you don't understand how serious this is, so let me break it down. In computer science there is a famous kind of puzzle called 3-SAT. You are given a long list of yes-or-no switches and a set of rules about how they must be arranged, and you have to find a combination that satisfies every rule. The obvious way to solve it is to try every combination, but each new switch doubles the number of possibilities, so a puzzle with a few hundred switches would take longer than the age of the universe to brute force. For decades, the smartest people in the field found clever tricks that made this a little faster, but every trick still hit the same wall: the time required kept exploding as the puzzle grew. About 25 years ago, two computer scientists, Russell Impagliazzo and Ramamohan Paturi, working with Francis Zane, turned that wall into a formal idea. They proposed the Exponential Time Hypothesis, which says this explosion is not a failure of human cleverness but a law of nature. No algorithm, however brilliant, will ever solve 3-SAT without the time blowing up exponentially. Nobody could prove it, but almost everyone believed it, and it became one of the foundations of modern computer science. Researchers used it as a measuring stick. If you could show that solving some other problem quickly would also crack 3-SAT quickly, you had shown that problem was hopelessly hard too. Hundreds of papers, across scheduling, graphs, logic and much more, rest on this one assumption. Now an internal AI model at OpenAI claims to have broken it. It says it found an algorithm that solves these puzzles meaningfully faster than the hypothesis allows, and it has checked the proof in a computer verification system called Lean. And here is the remarkable part: the very people who proposed the hypothesis, Impagliazzo and Paturi, along with MIT's Ryan Williams, are now leading the public review of whether a machine has disproved their own idea. So what happens next? If the disproof holds, a large part of theoretical computer science has to be revisited. Every result that said "this problem cannot be solved faster, assuming ETH" loses its foundation, and researchers will have to work out which of those walls were real and which were simply where we stopped looking. It does not mean everything becomes easy. The new algorithm is still slow in absolute terms and this is not the famous P versus NP problem being solved. But it means our map of what is possible was wrong in a place we were very confident about, and it was an AI that redrew it. If the disproof fails, the hypothesis survives and the field breathes out, but we will still have watched an AI produce serious, checkable work on one of the deepest questions in the discipline, closely enough that the founders of the idea had to take it seriously. Either way, something has shifted.
An internal model at OpenAI has produced a claimed refutation of ETH! Russell Impagliazzo, Mohan Paturi, and I have been asked to help organize an open and independent examination of this claim. 1/4
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This would be the biggest discovery in computational computer science. Slight crack in everyone’s confidence too about P=NP problem.
An internal model at OpenAI has produced a claimed refutation of ETH! Russell Impagliazzo, Mohan Paturi, and I have been asked to help organize an open and independent examination of this claim. 1/4
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The socialists and deep state have won. It’s a one way ratchet. Say what you want but is indisputable.. Check out this story: Guns or Butter? (found on beelineblogger.blogspot.com/…)
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zipjet retweeted
The videos emerging from Africa of Islamists slaughtering Christians are truly satanic. I have seen a video of Jihadists cutting the limbs off young Christian men and women before beheading them. I genuinely don't understand why nobody is talking about this.
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October 21 at 1:42 PM · MISSOURI HAS NO ILLEGALS; go figure... shouldn't the other states do the same? Missouri's approach to the problem of illegal immigration appears to be more advanced, sophisticated, strict, and effective than anything to date in Arizona. Does the White House appreciate what Missouri has done? So, why doesn't Missouri receive attention? Answer: There are no illegals in Missouri to demonstrate. (And the Media doesn't want to publicize that fact!) The "Show Me" state has again shown us how it should be done. There needs to be more publicity and exposure regarding what Missouri has done. Please pass this around. In 2007, Missouri placed on the ballot a proposed constitutional amendment designating English as the official language of Missouri. In November 2008, nearly 90% voted in favor! Thus, English became the official language for ALL governmental activity in Missouri. No individual has the right to demand government services in a language OTHER than English. In 2008, a measure was passed that required the Missouri Highway Patrol and other law enforcement officials to verify the immigration status of any person arrested, and inform federal authorities if the person is found to be in Missouri illegally. Missouri law enforcement officers receive specific training with respect to enforcement of federal immigration laws. In Missouri, illegal immigrants do NOT have access to taxpayer benefits such as food stamps or health care through Missouri Health NET. In 2009, a measure was passed that ensures Missouri's public institutions of higher education do NOT award financial aid to individuals who are illegally in the United States. In Missouri, all post-secondary institutions of higher education are required to annually certify to the Missouri Dept. of Higher Education that they have NOT knowingly awarded financial aid to students who are unlawfully present in the United States . It is important to remember, Missouri has been far more proactive in addressing this horrific problem. Missouri has made it clear that illegal immigrants are NOT WELCOME in the state and they will NOT receive public benefits at the expense of Missouri taxpayers. DON'T DELETE THIS, AMERICA. KEEP IT GOING UNTIL WE GET ALL 50 STATES TO COMPLY!
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