Pain neuroscientist and electrophysiologist. Trying to understand how neurons are wired into circuits. New PI at WashU in St. Louis https://xitter.gq/t.co/TPrJaftjlu
Joined October 2017
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We're really excited about this project! To piggyback off of @NeuroTejeda's tweet, we're also hiring. Please reach out if you're interested in protein engineering, slice electrophysiology, and/or high throughout screening.
Great people doing incredible science in a fun and collaborative group. I cannot recommend Rob's lab enough
3 postdocs landing dream jobs, 1 PhD student graduating means: A)I'm so proud of these amazing scientists and happy for their success & B) We have opportunities to recruit new colleagues!
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Our work to build an atlas of human cell types in the spinal cord and periphery was just funded! Come do a postdoc with us to work on HUMAN neurons using ephys, sequencing, and 2p imaging to understand how they are affected by pain and substance use disorders. Please RT!
We are very excited to launch the new INTERCEPT pain program here at @WashUPain @WUSTL_AnesRsrch. We will study human biology to provide new insights critical for developing new treatments for #chronicpain. medicine.wustl.edu/news/unde…
Absolutely spot on.
Feels like a good time to remind any @WUSTLmed
@WashUanesthesia trainees that there are faculty who care deeply about your well-being. Sunlight is a great disinfectant (to use the laundry analogy) and you can connect with trained faculty committed to improving our culture here.
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AAVs to express PPO for inhibiting synaptic projections in vivo are now available from Addgene. If anyone has any questions about using them for your terminals of interest, please reach out!
Plasmids from @mbruchas: A photoswitchable GPCR-based opsin for presynaptic silencing.
hubs.la/H0-jKZn0
ALT Schematic showing switching of the GPCR with UV light
If you're soon a soon to be graduating pharmacologist and/or electrophysiologist, you should go work with Dave, he's fantastic!!!
On behalf of twitter-less Dr. Dave MacLean: the MacLean Lab at @urochestermed is looking for a postdoctoral candidate! Attached is a letter with more info. TL;DR talented scientists with backgrounds in genetic code expansion, ephys and/or fluorescence techniques should apply!
India did a fantastic job in the lab initiating a new project. And we're really excited she's going to continue this project when school starts back up! For anyone interested in this program please get in touch and apply next year. We'd love to have you join us!
diversity.med.wustl.edu/anes… The ASSURE program was a great success. The students were engaged, dedicated, and productive. Their scientific presentations were truly excellent.
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This is an excellent example of how we can begin to develop a mechanistic understanding of neurological disorders using individual patient sequencing. Congrats to everyone involved!
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Really excited to see this version out! We have struggled for years with terminal optogenetic inhibition, and thanks to insights from @M__Mahn and @OferYizhar we began to rethink the use of ion-based opsins for these applications. We took advantage of light sensitive GPCRs...
We continue developing "opto-GPCRs" for neuromodulatory control, this Gi version provides spatiotemporal control of pre-synaptic silencing. Stay tuned. Thanks to @BryanCopits @robgereau @outRaajeous @_SpaceKase_ @NIH #braininitiative Available @Addgene
biorxiv.org/content/10.1101/…
that have evolved unique optical properties in nature, we used the inhibitory lamprey parapinopsin for photoswitchable control of synaptic transmission. This has been another great collaboration between the @robgereau and @mbruchas labs! Thanks to the many co-authors...
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This is really exciting and groundbreaking work to understand the molecular basis of pain and somatosensory processing in human neurons.
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We hope that this is a great chance to get some research experience this summer. Please come join us!
This summer research fellowship for URM students offers 10 weeks of research and mentoring career development/support. ASSURE students receive a $6,500 stipend, plus paid on campus housing and local transportation for the summer. Please share with any students in the #StL region!
I can't wait to share work at this fantastic panel. Please come join us Tuesday at 6 pm EST, 3 pacific
Check out @KerriPryce’s posterM148 today on transcriptomic effects of oxycodone. Also, our panel on Circuits and Intracellular Pathways mediating pain and opioid actions with @AmynahPradhan @BryanCopits and Julie Kauer!
#ACNP2020.
I'm very proud that our department has taken action and established this program to increase inclusion and representation of underrepresented groups in science. Please help spread the word, we would love to have you join us!
Very excited to announce the launch of our new departmental summer research fellowship program for college students in the St Louis region. #STLMade anesthesiology.wustl.edu/ane…
Congrats to former #Gereaulab undergrad and superstar neuroscientist @WillifordKellie on being awarded an F99/K00! Any lab looking for a great future postdoc should look no further.
Such a whirlwind of emotions rn. SO excited to announce I got the #DSPAN F99/K00 grad-to-postdoc transition award! Praising God for this blessing
Also crushed but unsurprised by continued injustice in this country. #BreonnaTaylorWasMurdered
Being #BlackInNeuro is feeling both
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Don't miss this great set off talks, including data from an exciting new tool for neural circuit sliencing from @Vijay_Samineni!
It is not to late to register for this Friday's virtual #pain2020 workshop. 4 great talks, takes only an hour of your time, discussions via Zoom and Slack. Register now (free) to get the zoom link: gulfcoastconsortia.org/event…
Please RT
I couldn't agree more! Congrats @robgereau!
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I've yet to experience this one. Can anyone else chime in?
Has anyone else had problems with Clampfit crashing after adjusting the baseline of traces? I cleared the registry and reset to default settings and that seemed to work for a while but the problem keeps coming back. Anyone have any fixes? I'm about to go mad. #ephys #patchclamp
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Absolutely, check out the amazing everything that @doctheagrif does!
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Check out this new assay from the Davidson lab that incorporates both operant and pain behaviors.
It's cheap and easy to build and use. Results may surprise.
The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice eneuro.org/content/early/202…
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