Neuroimmunologist, studying chemotherapy-induced neurotoxicities at MD Anderson Cancer Center. Views are my own.
Houston, TX
Joined June 2009
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Dr. Annemieke Kavelaars retweeted
It’s been a year since the Supreme Court overturned Roe v. Wade. Since then, 14 states have banned most abortions, leaving millions of women and girls with nowhere to turn for the care they need.
And yet, there are reasons to hope.
After Roe v. Wade was overturned, voters in Michigan, California, and Vermont helped enshrine abortion rights in their state constitutions. And governors in states like Nevada, Hawaii, and Pennsylvania have signed executive orders to protect abortion access.
Dr. Annemieke Kavelaars retweeted
We have two exciting postdoc opportunities in the lab to study mechanisms of chemotherapy-induced neuropathy, and autoimmune mechanisms of chronic pain postdocjobs.com/posting/7125… postdocjobs.com/posting/7125…. DM me for more details!
In case you are ready for a break. This is the debut album of my brother in law. open.spotify.com/album/7fQc2…
Dr. Annemieke Kavelaars retweeted
Above all, I dare you to do good
So that the world might be great.
"I only ask that you care before it’s too late,
That you live aware and awake,
That you lead with love in hours of hate."
At #UNGA, poet, activist & @unicef supporter @theamandagorman shared a powerful poem calling for urgent action to achieve the #GlobalGoals.
Dr. Annemieke Kavelaars retweeted
Congrats @JixiangZhang1 this a great piece of work showing that an HDAC6 inhibitor only apparently reverses chemo pain. In fact, the inhibitor induces tonic ENK-delta opioid receptor signaling to suppress ongoing mechanical hypersensitivity.
Very pleased to share our recent work: HDAC6 inhibition reverses cisplatin-induced mechanical hypersensitivity via tonic delta opioid receptor signaling. Thank you so much @akavel @CobiHeijnen @DrPeterGrace ! jneurosci.org/content/early/…
Dr. Annemieke Kavelaars retweeted
Very pleased to share our recent work: HDAC6 inhibition reverses cisplatin-induced mechanical hypersensitivity via tonic delta opioid receptor signaling. Thank you so much @akavel @CobiHeijnen @DrPeterGrace ! jneurosci.org/content/early/…
Dr. Annemieke Kavelaars retweeted
Another great paper examining neuroimmune mechanisms of CIPN from @akavel @GeoffroyLaumet and others. Interplay between CD8+ T-cell derived IL-13 and macrophage IL-10 is quite interesting #pain insight.jci.org/articles/vie…
Dr. Annemieke Kavelaars retweeted
CD8+ T cell–derived IL-13 increases macrophage IL-10 to resolve neuropathic pain: buff.ly/3MHiC4o
@akavel @MDAndersonNews
#Neuroscience
New paper in @JCI_insight: CD8 T cells and M2 macrophages collaborate to resolve pain. IL13 and IL10 are the players. doi.org/10.1172/jci.insight.… By Susmita K. Singh with @karenkrukowski @GeoffroyLaumet @CobiHeijnen @JenolynF_A @MDAndersonNews
CD8 T cells and M2 macrophages collaborate to promote resolution of pain. IL13 and IL10 are key. Susmita K. Singh, @GeoffroyLaumet @karenkrukowski @CobiHeijnen @JenolynF_A doi.org/10.1172/jci.insight.…
Dr. Annemieke Kavelaars retweeted
The next workshop in our #Pain2022 series is THIS FRIDAY! Bin Feng, Nick Spencer, @OliviaEllerPhD @Vijay_Samineni Register here: eventbrite.com/e/february-pa…
Dr. Annemieke Kavelaars retweeted
To prevent the long term cognitive side effects of some chemotherapies, scientists have developed a nasal therapy that delivers coated mitochondria to reverse neurotoxicity.
@JenolynF_A @CobiHeijnen @akavel @A_Seua
Learn more: ow.ly/LtIU50HQNBH
Dr. Annemieke Kavelaars retweeted
Targeting the meninges with nasal delivery of functionalized mitochondria resolves #chemotherapy induced cognitive deficits & signs of #pain ! Here’s how we did it @CobiHeijnen @akavel @A_Seua &others @MDAndersonNews @AdvSciNews
onlinelibrary.wiley.com/shar…
#neuroscience #nano
Dr. Annemieke Kavelaars retweeted
Excited to share our latest research: macrophages, IL10, HDAC6 and Pain. Thanks for the greatest team and mentors. Dr Annemieke Kavelaars @akavel Dr Cobi Heijnen @CobiHeijnen and Vicky @jiacheng_ma . sciencedirect.com/science/ar…
Dr. Annemieke Kavelaars retweeted
Pain resolving macrophages: Macrophages resolve inflammatory pain by donating their mitochondria to sensory neurons.
Team work with @MichielVlist @RaoofRamin @HLDMWillemen @LindeMeyaard. Proud! Such a fun, cool and inspiring collaboration.
authors.elsevier.com/a/1eGBX…
A thread.1/n
Blake McAlpin currently defending his thesis on HDAC6 inhibition to treat chemobrain in mice
HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity thno.org/v12p0603.htm #Theranostics long lasting changes in microglia after chemotherapy. @CobiHeijnen @MDAndersonNews
HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity thno.org/v12p0603.htm #Theranostics long lasting changes in microglia after chemotherapy. @CobiHeijnen @MDAndersonNews
Dr. Annemieke Kavelaars retweeted
This comes just one day after @GOPLeader announced his intent to reward white supremacist members of Congress who incite violence.
Same party who just appointed 200+ judges, many unqualified, to federal courts- 70% of whom were white men.
And that’s just scratching the surface.
Dr. Annemieke Kavelaars retweeted
In a new Viewpoint, Kavelaars (@akavel) and Heijnen (@cobiheijnen) assess the dual, sometimes conflicting roles of the #ImmuneSystem in regulating #pain, noting that T cells and macrophages can be either friends or foes depending on the specific context. fcld.ly/t2gwang
