Matt Daugherty retweeted
I am delighted to share the latest preprint from our lab, which was work that was conceived and led by @JTenthorey during her postdoc and during the first few months of her independent lab at UCSF.
biorxiv.org/content/10.1101/…
TL;DR: Indels matter. A lot.
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Matt Daugherty retweeted
New work from our @ASAP_Research team: nature.com/articles/s41594-0…. Parkinson’s disease-linked LRRK2’s closest relative, LRRK1 is tightly regulated via different mechanisms than LRRK2. Great collaboration with @aleschziner, @Daugherty_Lab, and Knapp labs
Matt Daugherty retweeted
Also, check out my episode of “Let’s Meet the Virologists” to learn a little about me and my career. Thanks to @lbthackray for having me on!
Replying to @AmerSocVirol
Meet Dustin Glasner @drglasner who studies the interface between #viruses and #innate_immunity. Check out his #ASV2023 Talk W8-1: Recognition of non-self viral mRNAs by the IFIT2 and IFIT3 heterodimer #LoveVirology lmtv.podbean.com/e/lmtv-epis…
Matt Daugherty retweeted
With #ASV2023 only a few days away, this seems like a good time to resurface here on Twitter. Come hear all about my research with @Daugherty_Lab on Saturday in the Innate Immune workshop. Can’t wait to connect with my fellow virologists for the first time since 2016!
Matt Daugherty retweeted
Innate immune #CARD8 mechanism for sensing #coronavirus & #picornavirus infection by detecting activity of #virus-encoded proteases; genetic variants in mammalian hosts affect which viruses can be sensed @BriBerryTea @psmitchej @Daugherty_Lab #PLOSBiology plos.io/43S8JZk
Matt Daugherty retweeted
Biologists led by the @Daugherty_Lab have identified a previously unknown way that our immune system detects viruses. The immune protein CARD8 acts as a trip wire to detect a range of viruses, including the virus that causes COVID. today.ucsd.edu/story/researc… @PLOSBiology
Matt Daugherty retweeted
Got a chance to share our story on a podcast with @Daugherty_Lab! Also my first time speaking on a podcast 🥳
Check it out here - open.spotify.com/episode/1NL…
Chinmay Kalluraya and Matthew Daugherty explain how vertebrates acquired a gene critical for vision from bacteria in the latest Science Sessions podcast: ow.ly/an8a50OurhW
Matt Daugherty retweeted
Chinmay Kalluraya and Matthew Daugherty explain how vertebrates acquired a gene critical for vision from bacteria in the latest Science Sessions podcast: ow.ly/an8a50OurhW
Matt Daugherty retweeted
Bacterial genetic origin in vertebrate eye evolution: @atnjoly recommends this @ChinmayK98 @Daugherty_Lab study in @PNASNews that finds interphotoreceptor retinoid-binding protein was inherited by horizontal gene transfer into the vertebrate genome
facultyopinions.com/article/…
Matt Daugherty retweeted
A new study shows that IRBP, a protein necessary for vision in vertebrates, was acquired from bacteria over 500 million years ago. @Daugherty_Lab @ChinmayK98
@PNASNews article: ow.ly/B69l50NMksY
@ScienceMagazine digest: ow.ly/9JJI50NMksZ
Matt Daugherty retweeted
Eye-opening origin story: Scientists traced the origin of a unique vision protein back 500 million years to bacteria. “It’s a massive shift because this is an entirely new piece of genetic material that’s been introduced from bacteria." - @Daugherty_Lab
today.ucsd.edu/story/eye-ope…
Matt Daugherty retweeted
For #SeeingDiversity we’re featuring @dalexstevens! As a grad student w @SamReckPeterson Alex focuses on using evolutionary guided approaches w the @Daugherty_Lab to uncover novel conflicts btw viruses & the host intracellular trafficking machinery, illustrated here by @GraceIHsu
Matt Daugherty retweeted
Replying to @dalexstevens
@dalexstevens in an awesome collaboration with Chris Beierschmitt in the @Daugherty_Lab shows that the dynein activating adaptor-NINL-plays a role in the interferon response to viral infections. Some viruses can “knock out” NINL through cleavage with their 3C or 3C-like proteases
Genetic signatures uncover the way viruses target a protein which helps to haul cargo across cells. elifesciences.org/digests/81…
Matt Daugherty retweeted
New preprint! Parkinson’s Disease-linked LRRK2 and non-PD-linked LRRK1 have distinct mechanisms for regulating their kinase activity. Awesome @ucsdbiosciences collaboration with @aleschziner and @Daugherty_Lab supported by @ASAP_Research.
biorxiv.org/content/10.1101/…. 1/2
Matt Daugherty retweeted
Great story from a great collaboration @ Twitterless Chris @Daugherty_Lab @SamReckPeterson
Genetic signatures uncover the way viruses target a protein which helps to haul cargo across cells. elifesciences.org/digests/81…
Matt Daugherty retweeted
Genetic signatures uncover the way viruses target a protein which helps to haul cargo across cells. elifesciences.org/digests/81…
Matt Daugherty retweeted
I dessed as the Red Queen Hypothesis for Halloween this year. I was only missing a treadmill (so I could do all the running I could...)
Matt Daugherty retweeted
💥Our new paper just out @ScienceMagazine!
Antiviral activity of a human protein of retroviral origin
A study led fearlessly by @jofrank1088
We propose that the human genome encodes a deep pool of antiviral proteins derived from retroviruses!
science.org/doi/10.1126/scie…
Matt Daugherty retweeted
Thrilled to announce (on behalf of @HHMINEWS Hanna Gray Fellow @ArielleWoznica, who is too humble) the opening of the Woznica Lab at UT Austin in Jan! 🎉 Job openings (see woznicalab.com) for undergrads or techs interested in a cool model system and an amazing mentor.
Matt Daugherty retweeted
Thrilled to announce two openings for tenure track faculty positions in the Department of Pathobiology @pennvet. Come join our vibrant, dynamic, innovative research community of outstanding colleagues and mentors. Apply here: apply.interfolio.com/115308.



























