@DavenportLab

Researching GPCRs and their ligands in human cardiovascular health and disease. Group Leader: Prof Anthony Davenport

 Cambridge, England
emit.medschl.cam.ac.uk/people/investigators/dr-anthony-davenport/
Joined January 2017
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Our latest review of approved & investigational drugs including in combination with SGLT2 inhibitors now in Nature Cardiovascular Research:Current and future strategies for targeting the endothelin pathway in cardiovascular disease nature.com/articles/s44161-0… rdcu.be/dp7Q8

Current and future strategies for targeting the endothelin pathway in cardiovascular disease

Nature Cardiovascular Research - Abraham and colleagues review the recent developments and future strategies to therapeutically target the endothelin pathway for a broad spectrum of cardiovascular...

nature.com
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Congratulations to our PI, Prof Anthony Davenport who has been ranked one of the 2020 highest cited researchers (top 1% by citations for field and year in Web of Science) for two consecutive years...@Catz_Cambridge @Cambridge_Uni recognition.webofscience.com…
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Congratulations to our PI, Professor Anthony Davenport who has been awarded Honorary Fellowship by the British Pharmacological Society. bps.ac.uk/publishing/blog/no…
St Catharine's College@Catz_Cambridge2 Dec 2020
For excellence & leadership in science, healthcare & public service, @BritPharmSoc has awarded Honorary Fellowships to Prof. Peter Barnes, Catz Honorary Fellow since 2011, & Prof. Anthony Davenport, Catz Fellow since 1995: caths.cam.ac.uk/bps-honorary… @ImperialNHLI @DavenportLab
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A survey has revealed that 40% of early career researchers funded by charities like @TheBHF have considered leaving research over funding concerns. @hmtreasury & @RishiSunak need to support #ResearchAtRisk. I don’t want to hang up my lab coat for good. bit.ly/31MCeOE

Pandemic threatens future of research as early career scientists look to leave

Four in ten charity-funded early career scientists have considered leaving research due to funding concerns since the coronavirus hit the UK, according to a survey by the Association of Medical...

bhf.org.uk
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Our latest paper could help explain why age is major risk factor for dying from COVID-19, with people over 70 years at greatest risk, and why the disease can cause heart complications in severe cases. sciencedirect.com/science/ar… @Cambridge_Uni @Catz_Cambridge
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Dagger to the heart: Genes encoding ACE2 and related proteins mediating SARS-CoV-2 viral entry are upregulated with age in human cardiomyocytes. @Cambridge_Uni @Catz_Cambridge biorxiv.org/content/10.1101/…

Genes Encoding ACE2, TMPRSS2 and Related Proteins Mediating SARS-CoV-2 Viral Entry are Upregulated...

Age is an independent risk factor for adverse outcome in patients following COVID-19 infection. We hypothesised that differential expression of genes encoding proteins proposed to be required for...

biorxiv.org
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Check out our latest paper in Nature drug discovery on advances in the GPCR-targeted peptide therapeutics...@Catz_Cambridge @Cambridge_Uni nature.com/articles/s41573-0…

Advances in therapeutic peptides targeting G protein-coupled receptors

Nature Reviews Drug Discovery - Many G protein-coupled receptors (GPCRs) have endogenous peptide agonists, and modifying the sequence of these peptides has led to some successful therapeutics. In...

nature.com
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Our latest paper where we showed for the first time the metabolism of apelin in human and identified novel metabolites has been published. Thanks to everyone who contributed to it. @Cambridge_Uni @Catz_Cambridge nature.com/articles/s41598-0…
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It’s the final day and we’re starting off with a symposium on our favourite things - GPCRs! #Pharmacology2019 @BritPharmSoc
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All set for day 2! #Pharmacology2019 @BritPharmSoc
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Our PhD students, Mene, Tom and Robyn, have been busy presenting their work at #Pharmacology2019 @BritPharmSoc @Cambridgecardio @Cambridge_Uni
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Ready to go at the first day of #pharmacology2019 ! @BritPharmSoc
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Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G Protein Biased Ligands at the Apelin Receptor. zpr.io/tPA9f Peptides #GPCR #signaling #pharmacology

Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G...

Apelin-36-[L28A] and apelin-36-[L28C(30kDa-PEG)] are G protein biased ligands of the apelin receptor, suggesting that the apelin receptor is an important therapeutic target in metabolic diseases.

pubmed.ncbi.nlm.nih.gov
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A fantastic two days at @BSCResearch Autumn Meeting 2019! Very interesting and inspiring talks! Our PhD students Tom and Robyn presented their work at the poster session. Congratulations to Robyn for winning a prize for her poster! @Cambridge_Uni @Catz_Cambridge @TheBHF
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Congratulations to our group leader Dr Anthony Davenport on his graduation as Doctor of Science today!! Very well deserved, we're all very proud 🥳🥳🥳 @Cambridge_Uni @Catz_Cambridge
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Well done to our PhD student, Robyn, who completed the BHF London to Brighton 54-mile bike ride yesterday! She was part of a group of BHF-funded Cambridge PhD students, who have collectively raised over £1,000! @Cambridgecardio @Cambridge_Uni @Catz_Cambridge
British Heart Foundation@TheBHF16 Jun 2019
Huge congratulations to our amazing researchers from Cambridge who absolutely smashed it! #LondonToBrighton
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Two of our PhD students, Tom and Robyn, and rotation student, Elisabeth, presenting their work at the poster session at #BASBSCRSpring2019 meeting @BSCResearch @britathsoc @Cambridgecardio - some great talks over the last two days!
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Davenport_Lab retweeted
Catrin Nye@CatrinNye15 May 2019
Parenting tips from the cat... xitter.cf/Mr_Meowwwgi/status/112…
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Check out our latest paper on a novel G protein biased apelin agonist which has beneficial effects in pulmonary hypertension doi.org/10.1111/bph.14603. @Cambridge_Uni @Catz_Cambridge
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Well done all!
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